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The map label for this gene is gsiC [H]

Identifier: 187928343

GI number: 187928343

Start: 1344641

End: 1345564

Strand: Direct

Name: gsiC [H]

Synonym: Rpic_1254

Alternate gene names: 187928343

Gene position: 1344641-1345564 (Clockwise)

Preceding gene: 187928342

Following gene: 187928344

Centisome position: 34.11

GC content: 62.01

Gene sequence:

>924_bases
ATGCTGAACTACTTCATTAAACGTGCGCTGGGCGTGATCCCGACACTGCTGATCGTGGCAGTGCTGGTGTTCCTGTTCGT
GCATCTGTTGCCCGGCGACCCGGCGCGTTTGGCCGCCGGCCCCGAAGCGGACGAGATGACGGTCGATCTCGTCCGCAAGG
ACCTGGGCCTGGACAAGCCGATGCACGAGCAGTTCGTGCGCTTCTTCGCCAACGCCGCACGTGGTGAATTCGGCAACTCC
ATCCGCACCAAGCGCCCGGTGAGCGAAGAGATTGGCGAACGCTTCTGGCCGACGCTCAATCTGACGATCACCAGCATGGT
GTGGGCGGTGATCTTCGGCATGGTGATCGGCATCACATCCGCCGTGTGGCGCAACAAGTGGCCTGACCGCCTGGGCATGA
CGCTCGCCGTGTCGGGCATCTCGTTCCCCGCGTTCGCACTGGGCATGCTGCTGATGGAAGTGTTCTCGGTGCAGCTTGGC
TGGCTGCCAGCCATCGGTGCGGACACCTGGAAGCACTACATCCTGCCTTCGCTCACGCTGGGCGCTGCAGTGGCTGCCGT
GATGGCGCGCTTCACGCGTGCGTCGTTCGTGGAAGTGCTGCAGGAAGATTTCGTGCGCACCGCCCGTGCCAAGGGCGTGC
GCGAGACTGTGGTGGTCATCAAGCATTGCCTGCGCAACGCGATGATCCCGGTGGTCACGATGATGGGCCTGCAGTTCGGT
TTTCTGCTGGGCGGCTCGATCGTCGTGGAGAAGGTGTTCAACTGGCCAGGCCTCGGCCGTCTGCTGGTGGATGCGGTGGA
AATGCGCGACTACCCGGTCATCCAGGCCGAGGTGCTGCTGTTCTCGCTGGAGTTCATCCTGATCAACCTTGTGGTGGACA
TGCTGTACACCGTCATCAACCCCACCATCCGCTACAAAAAGTAA

Upstream 100 bases:

>100_bases
CAGCTTCGACGACATCGACGTCAAGCAATAAGCCTCATTGCCGTACCGGCCCGCGCAGCCTTGCGCGGGCCATTGAAATG
CCGCCTGCGGTGGATTTGCC

Downstream 100 bases:

>100_bases
GGAGGCCGCCATGACCCAAGCCGCAAGCCAGGCGGTCGCACCGCAAGCCGCCACCGAACCCGTTCGCACCCCCTGGACGG
AGTTCTGGCGCAAGTTCCGC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLNYFIKRALGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEMTVDLVRKDLGLDKPMHEQFVRFFANAARGEFGNS
IRTKRPVSEEIGERFWPTLNLTITSMVWAVIFGMVIGITSAVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPAIGADTWKHYILPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVIKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDMLYTVINPTIRYKK

Sequences:

>Translated_307_residues
MLNYFIKRALGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEMTVDLVRKDLGLDKPMHEQFVRFFANAARGEFGNS
IRTKRPVSEEIGERFWPTLNLTITSMVWAVIFGMVIGITSAVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPAIGADTWKHYILPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVIKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDMLYTVINPTIRYKK
>Mature_307_residues
MLNYFIKRALGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEMTVDLVRKDLGLDKPMHEQFVRFFANAARGEFGNS
IRTKRPVSEEIGERFWPTLNLTITSMVWAVIFGMVIGITSAVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLG
WLPAIGADTWKHYILPSLTLGAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVIKHCLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDMLYTVINPTIRYKK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=78.7581699346405, Blast_Score=499, Evalue=1e-143,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=41.4705882352941, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1789888, Length=311, Percent_Identity=37.2990353697749, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787761, Length=326, Percent_Identity=38.6503067484663, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1787497, Length=311, Percent_Identity=35.048231511254, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1787550, Length=276, Percent_Identity=31.5217391304348, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=27.2727272727273, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34255; Mature: 34255

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYFIKRALGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEMTVDLVRKDLGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCH
MHEQFVRFFANAARGEFGNSIRTKRPVSEEIGERFWPTLNLTITSMVWAVIFGMVIGITS
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLGWLPAIGADTWKHYILPSLTL
HHHHCCCCHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVIKHCLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDMLYTVIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYKK
CCCCCCC
>Mature Secondary Structure
MLNYFIKRALGVIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADEMTVDLVRKDLGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCH
MHEQFVRFFANAARGEFGNSIRTKRPVSEEIGERFWPTLNLTITSMVWAVIFGMVIGITS
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AVWRNKWPDRLGMTLAVSGISFPAFALGMLLMEVFSVQLGWLPAIGADTWKHYILPSLTL
HHHHCCCCHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GAAVAAVMARFTRASFVEVLQEDFVRTARAKGVRETVVVIKHCLRNAMIPVVTMMGLQFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLGGSIVVEKVFNWPGLGRLLVDAVEMRDYPVIQAEVLLFSLEFILINLVVDMLYTVIN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTIRYKK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA