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The map label for this gene is moaE [H]

Identifier: 187928296

GI number: 187928296

Start: 1294443

End: 1294964

Strand: Direct

Name: moaE [H]

Synonym: Rpic_1207

Alternate gene names: 187928296

Gene position: 1294443-1294964 (Clockwise)

Preceding gene: 187928295

Following gene: 187928297

Centisome position: 32.83

GC content: 64.37

Gene sequence:

>522_bases
ATGTCCGTCCGCGTACAGGAAGCCGACTTCGACCTCGGCGCCGAGATTGCAGCGCTCCGTGCCGGCCGCCCGAACATTGG
CGCGGTGGCCAGCTTCATCGGCACGGTGCGAGATATCAACGACGGCACAGGTGTGTCGGAGATGGAGCTGGAGCACTATC
CCGGCATGACCGAAAAGGCGCTCGCCGATATTGTGAGCGCGGCCATGCAGCGCTGGGAGCTGATCGACGCGCTTGTCATC
CACCGCGTTGGCAAGCTCAAGCCGCAAGACCAGATCGTGCTGGTGGCGGTCGCGTCCAAGCACCGCGGGGAATCCTTTGC
CGCGTGCGAATTCATCATGGATTACCTCAAGAGCGAGGCGCCGTTCTGGAAGAAGGAACAGACGCCCGAAGGCGCGCGCT
GGGTTGATGCGCGTGTCACCGACGACAAGGCGCTCGCCCGCTGGGGCATTGCCACCTCCAACGGCGCGGCGAGCACGGCC
AATCAGCCCGGCGCATCGGCGCAACCCAACGACTACGAATAA

Upstream 100 bases:

>100_bases
GTGGACCACCAGATCGTACCGGCCGATACCGCCGTGCACGACGGCTGCGAAGTCGCCTTCTTCCCGCCCGTGACCGGCGG
CTGAGCGCAGGAGACCGACC

Downstream 100 bases:

>100_bases
CAAGGACGCGACCGCATGAGCGGAATGGGCTTTCTGGCAGTTGGGGTGGGTGCTGCGCTGGGAGCCTGGTTGCGCTGGGC
GCTCGCCATCTTGTTGAACG

Product: molybdopterin biosynthesis MoaE protein

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSVRVQEADFDLGAEIAALRAGRPNIGAVASFIGTVRDINDGTGVSEMELEHYPGMTEKALADIVSAAMQRWELIDALVI
HRVGKLKPQDQIVLVAVASKHRGESFAACEFIMDYLKSEAPFWKKEQTPEGARWVDARVTDDKALARWGIATSNGAASTA
NQPGASAQPNDYE

Sequences:

>Translated_173_residues
MSVRVQEADFDLGAEIAALRAGRPNIGAVASFIGTVRDINDGTGVSEMELEHYPGMTEKALADIVSAAMQRWELIDALVI
HRVGKLKPQDQIVLVAVASKHRGESFAACEFIMDYLKSEAPFWKKEQTPEGARWVDARVTDDKALARWGIATSNGAASTA
NQPGASAQPNDYE
>Mature_172_residues
SVRVQEADFDLGAEIAALRAGRPNIGAVASFIGTVRDINDGTGVSEMELEHYPGMTEKALADIVSAAMQRWELIDALVIH
RVGKLKPQDQIVLVAVASKHRGESFAACEFIMDYLKSEAPFWKKEQTPEGARWVDARVTDDKALARWGIATSNGAASTAN
QPGASAQPNDYE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=111, Percent_Identity=35.1351351351351, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1787003, Length=139, Percent_Identity=56.1151079136691, Blast_Score=155, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356259, Length=102, Percent_Identity=34.3137254901961, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18744; Mature: 18613

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVQEADFDLGAEIAALRAGRPNIGAVASFIGTVRDINDGTGVSEMELEHYPGMTEKA
CCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHH
LADIVSAAMQRWELIDALVIHRVGKLKPQDQIVLVAVASKHRGESFAACEFIMDYLKSEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PFWKKEQTPEGARWVDARVTDDKALARWGIATSNGAASTANQPGASAQPNDYE
CCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVRVQEADFDLGAEIAALRAGRPNIGAVASFIGTVRDINDGTGVSEMELEHYPGMTEKA
CCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHH
LADIVSAAMQRWELIDALVIHRVGKLKPQDQIVLVAVASKHRGESFAACEFIMDYLKSEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PFWKKEQTPEGARWVDARVTDDKALARWGIATSNGAASTANQPGASAQPNDYE
CCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]