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The map label for this gene is yfbQ [H]

Identifier: 187928290

GI number: 187928290

Start: 1288073

End: 1289314

Strand: Direct

Name: yfbQ [H]

Synonym: Rpic_1201

Alternate gene names: 187928290

Gene position: 1288073-1289314 (Clockwise)

Preceding gene: 187928277

Following gene: 187928291

Centisome position: 32.67

GC content: 62.0

Gene sequence:

>1242_bases
GTGAAAACGATCCAGAAATCCGCCAAGCTCAACAACGTCTGCTATGACATTCGCGGCCCAGTGCTCGAGAAGGCCAAGCA
GATGGAAGAAGACGGCCACAAGATCATCAAGCTGAATATCGGCAACCTTGCCCCATTCGGTTTCGATGCCCCGGAAGAGA
TCCAGCTGGACATAATCCGTAACCTGCCCAATTCGGCCGGCTATTCGGATTCCAAGGGCATCTTCGCGGCGCGCAAGGCG
GTGATGCACTACACGCAGGAACAGGGCATCAAGAACGTCACGCTGGACGACATCTATCTGGGCAATGGCGCGTCCGAGCT
GATTTCGCTGGCCACCAACGCGCTGCTCGATGCCGGCGACGAGCTGCTGCTGCCGGCTCCCGACTACCCGCTGTGGACCG
CCGTGACCAGCCTCTCGGGCGGCACGCCGGTGCACTACACGTGCGACGAAGCCAACGGCTGGATGCCGGACCTGGACGAC
ATCCGCGCCAAGATCACGCCCAACACCAAGGGCATCGTCGTCATCAACCCGAACAACCCGACCGGCGCATTGTATTCAGA
CGAGCTGCTGCTGGGCATCGTCGCCATTGCGCGGGAGCACGGCCTGGTGATCTTCGCCGATGAGGTGTACGACAAGGTTC
TGTTCGACGACAACAAGCACACCGCGATCGGTTCGCTGTCGGAAGACGTGCTGACGGTGACGTTCAACAGCCTCTCGAAG
AGCTACCGCTCGTGCGGTTACCGCGCGGGCTGGATGGTCGTGTCCGGCGACAAGCGCCCGGCCAAGGATTACATCGAAGG
CCTGAACATGCTCTCGTCGATGCGTCTGTGCGCTAACGTGCCGGGCCAGTGGGCGATCCAGACCGCGCTGGGCGGCTACC
AGAGCATCAAGGACCTGGTGGCGCCGGGCGGCCGCATGCGCCGTCAGCGCGACCTTGCGCACGAACTGATCACGGCGATT
CCGGGCGTGACCTGCGTGAAGCCCAAGGCTGCGCTGTATATGTTCCCGCGCCTGGACCCGGTGGTGTACCCGATCGAAGA
CGATCAGACCTTCATCCGCCAACTGCTGGAAGAAGAACGTGTGCTGCTGGTGCAGGGCACAGGCTTCAACTGGCACTCGC
CGGATCACTTCCGCATCGTCTTCCTGCCCCACGAAGACGACCTTCGCGAAGCGATCGGCCGAATTTCGCGCTTCCTGGAG
CGGTACCGTCAGCGTCACGGTACTGGCATCCGGGCCGCATAA

Upstream 100 bases:

>100_bases
CGGCGCCTGCCGCTGTGTGGCGTTACCGTCGCCGCTTTGCTGCGCCACAGAATGCCCCGTAGTTCAAGCCCGTTCAACGT
CGCCAATCGCCGCCTTGCCC

Downstream 100 bases:

>100_bases
CATCGGTCTTCCGCCAGATCAGTAATTGCGGGGCAGACCGAGGTGTCTGCCCTGTGTTTTTTTGCCTTTCGCTTTTTCGT
TTCTTTACGACACGTCTCAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEDGHKIIKLNIGNLAPFGFDAPEEIQLDIIRNLPNSAGYSDSKGIFAARKA
VMHYTQEQGIKNVTLDDIYLGNGASELISLATNALLDAGDELLLPAPDYPLWTAVTSLSGGTPVHYTCDEANGWMPDLDD
IRAKITPNTKGIVVINPNNPTGALYSDELLLGIVAIAREHGLVIFADEVYDKVLFDDNKHTAIGSLSEDVLTVTFNSLSK
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSIKDLVAPGGRMRRQRDLAHELITAI
PGVTCVKPKAALYMFPRLDPVVYPIEDDQTFIRQLLEEERVLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRISRFLE
RYRQRHGTGIRAA

Sequences:

>Translated_413_residues
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEDGHKIIKLNIGNLAPFGFDAPEEIQLDIIRNLPNSAGYSDSKGIFAARKA
VMHYTQEQGIKNVTLDDIYLGNGASELISLATNALLDAGDELLLPAPDYPLWTAVTSLSGGTPVHYTCDEANGWMPDLDD
IRAKITPNTKGIVVINPNNPTGALYSDELLLGIVAIAREHGLVIFADEVYDKVLFDDNKHTAIGSLSEDVLTVTFNSLSK
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSIKDLVAPGGRMRRQRDLAHELITAI
PGVTCVKPKAALYMFPRLDPVVYPIEDDQTFIRQLLEEERVLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRISRFLE
RYRQRHGTGIRAA
>Mature_413_residues
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEDGHKIIKLNIGNLAPFGFDAPEEIQLDIIRNLPNSAGYSDSKGIFAARKA
VMHYTQEQGIKNVTLDDIYLGNGASELISLATNALLDAGDELLLPAPDYPLWTAVTSLSGGTPVHYTCDEANGWMPDLDD
IRAKITPNTKGIVVINPNNPTGALYSDELLLGIVAIAREHGLVIFADEVYDKVLFDDNKHTAIGSLSEDVLTVTFNSLSK
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSIKDLVAPGGRMRRQRDLAHELITAI
PGVTCVKPKAALYMFPRLDPVVYPIEDDQTFIRQLLEEERVLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRISRFLE
RYRQRHGTGIRAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=470, Percent_Identity=28.5106382978723, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI215599424, Length=382, Percent_Identity=31.413612565445, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4507369, Length=395, Percent_Identity=26.0759493670886, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4885351, Length=470, Percent_Identity=26.1702127659574, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI95147551, Length=172, Percent_Identity=28.4883720930233, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI169881279, Length=172, Percent_Identity=28.4883720930233, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI56713254, Length=167, Percent_Identity=26.9461077844311, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI56713256, Length=167, Percent_Identity=26.9461077844311, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI169881281, Length=145, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=63.6138613861386, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1788722, Length=371, Percent_Identity=27.2237196765499, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=23.1770833333333, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790797, Length=364, Percent_Identity=25.2747252747253, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=28.6842105263158, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=474, Percent_Identity=24.2616033755274, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=309, Percent_Identity=25.8899676375405, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=309, Percent_Identity=25.8899676375405, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=25.7627118644068, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=177, Percent_Identity=28.2485875706215, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=386, Percent_Identity=30.8290155440415, Blast_Score=149, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6323118, Length=401, Percent_Identity=27.431421446384, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6322401, Length=182, Percent_Identity=31.8681318681319, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859735, Length=397, Percent_Identity=26.448362720403, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45551451, Length=468, Percent_Identity=26.2820512820513, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641770, Length=489, Percent_Identity=25.9713701431493, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641760, Length=489, Percent_Identity=25.9713701431493, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641768, Length=489, Percent_Identity=25.9713701431493, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641766, Length=489, Percent_Identity=25.9713701431493, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641764, Length=489, Percent_Identity=25.9713701431493, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573069, Length=166, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24646114, Length=166, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28573067, Length=166, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28573065, Length=166, Percent_Identity=26.5060240963855, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45809; Mature: 45809

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEDGHKIIKLNIGNLAPFGFDAPEEIQLDIIR
CCCHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
NLPNSAGYSDSKGIFAARKAVMHYTQEQGIKNVTLDDIYLGNGASELISLATNALLDAGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECEEEECCCHHHHHHHHHHHHHCCCC
ELLLPAPDYPLWTAVTSLSGGTPVHYTCDEANGWMPDLDDIRAKITPNTKGIVVINPNNP
CEEECCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHCEEEECCCCCEEEEECCCCC
TGALYSDELLLGIVAIAREHGLVIFADEVYDKVLFDDNKHTAIGSLSEDVLTVTFNSLSK
CCCEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSIKDLV
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHH
APGGRMRRQRDLAHELITAIPGVTCVKPKAALYMFPRLDPVVYPIEDDQTFIRQLLEEER
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCEEEECCCCHHHHHHHHCCCC
VLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRISRFLERYRQRHGTGIRAA
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTIQKSAKLNNVCYDIRGPVLEKAKQMEEDGHKIIKLNIGNLAPFGFDAPEEIQLDIIR
CCCHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
NLPNSAGYSDSKGIFAARKAVMHYTQEQGIKNVTLDDIYLGNGASELISLATNALLDAGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECEEEECCCHHHHHHHHHHHHHCCCC
ELLLPAPDYPLWTAVTSLSGGTPVHYTCDEANGWMPDLDDIRAKITPNTKGIVVINPNNP
CEEECCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCHHHCEEEECCCCCEEEEECCCCC
TGALYSDELLLGIVAIAREHGLVIFADEVYDKVLFDDNKHTAIGSLSEDVLTVTFNSLSK
CCCEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
SYRSCGYRAGWMVVSGDKRPAKDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSIKDLV
HHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHH
APGGRMRRQRDLAHELITAIPGVTCVKPKAALYMFPRLDPVVYPIEDDQTFIRQLLEEER
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCEEEECCCCHHHHHHHHCCCC
VLLVQGTGFNWHSPDHFRIVFLPHEDDLREAIGRISRFLERYRQRHGTGIRAA
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]