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The map label for this gene is fpr [H]

Identifier: 187928269

GI number: 187928269

Start: 1268968

End: 1269744

Strand: Direct

Name: fpr [H]

Synonym: Rpic_1180

Alternate gene names: 187928269

Gene position: 1268968-1269744 (Clockwise)

Preceding gene: 187928266

Following gene: 187928270

Centisome position: 32.19

GC content: 60.75

Gene sequence:

>777_bases
ATGTCCGCCTTCAATCAAGAGACCGTTCTGAGCGTCCATCACTGGAATGACTCGCTGTTCAGCTTCAAGACCACCCGCGA
CCAGGCGCTGCGCTTCCATAACGGCCACTTCGTCATGATCGGGCTGGAGGTCGAAGGCAAGCCGCTGATGCGCGCCTACA
GCATCGCGAGCCCGAACTACGAAGAGCACCTCGAGTTCTTCAGCATCAAGGTGCAGAACGGCCCCCTGACGTCGCGACTG
CAGCATCTGAAGGTGGGCGACAAGCTGCTGGTGAGCAAGAAGCCGGTCGGCACGCTCGTACTGGATGACCTGCTACCCGG
TAAGAACCTGTATCTGTTCGGCACCGGCACCGGCCTCGCGCCGTTCATGAGCATCATCCAGGACCCGGACACCTATGAGC
GCTTCGAGAAGGTCGTGCTGCTGCACGGCGTGCGCCAAGTGAGCGAGTTGGCTTATGCCGACTTCATCACCCGGGAATTG
CCGAACAACGAGTTCTTTGGCGATCAGGTGCGCGAAAAGCTGATCTATTACCCCACGGTTACGCGTGAGCCGTTCCGCAA
CATGGGCCGCCTGACGGACCTCGTCGACAGCGGCAAGCTGTCTGTCGATATCGGCCTGCCCCCGATGGATCCGGCAGTCG
ACCGCGCCATGATCTGTGGCAGCCCGGCCATGCTGGAAGACACCTGCAAGCTGCTCGACGACCGCGGTTTCAAGATCTCG
CCGCGCATGGGCGAAGCGGGTGACTACGTGATCGAGCGCGCCTTCGTCGAGAAATAA

Upstream 100 bases:

>100_bases
AGGCGCGGCCGCGGCGAATCGCATAAAATCAAGGCCTTGACCGATTTTTGCATCGCCACATAACCCGATTGAGCTTCATT
GGGTTGGCCCGAATGTCACC

Downstream 100 bases:

>100_bases
TCGATACGGCTTCTGTTGCAAACGCCGGCCTGGGTGCCGGCGTTTTGTTTTTGCCGGCGCCCCGGGCAATCCCGCGTCGG
CAAAGGCGATGCGGGCGGAT

Product: Oxidoreductase FAD-binding domain-containing protein

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSAFNQETVLSVHHWNDSLFSFKTTRDQALRFHNGHFVMIGLEVEGKPLMRAYSIASPNYEEHLEFFSIKVQNGPLTSRL
QHLKVGDKLLVSKKPVGTLVLDDLLPGKNLYLFGTGTGLAPFMSIIQDPDTYERFEKVVLLHGVRQVSELAYADFITREL
PNNEFFGDQVREKLIYYPTVTREPFRNMGRLTDLVDSGKLSVDIGLPPMDPAVDRAMICGSPAMLEDTCKLLDDRGFKIS
PRMGEAGDYVIERAFVEK

Sequences:

>Translated_258_residues
MSAFNQETVLSVHHWNDSLFSFKTTRDQALRFHNGHFVMIGLEVEGKPLMRAYSIASPNYEEHLEFFSIKVQNGPLTSRL
QHLKVGDKLLVSKKPVGTLVLDDLLPGKNLYLFGTGTGLAPFMSIIQDPDTYERFEKVVLLHGVRQVSELAYADFITREL
PNNEFFGDQVREKLIYYPTVTREPFRNMGRLTDLVDSGKLSVDIGLPPMDPAVDRAMICGSPAMLEDTCKLLDDRGFKIS
PRMGEAGDYVIERAFVEK
>Mature_257_residues
SAFNQETVLSVHHWNDSLFSFKTTRDQALRFHNGHFVMIGLEVEGKPLMRAYSIASPNYEEHLEFFSIKVQNGPLTSRLQ
HLKVGDKLLVSKKPVGTLVLDDLLPGKNLYLFGTGTGLAPFMSIIQDPDTYERFEKVVLLHGVRQVSELAYADFITRELP
NNEFFGDQVREKLIYYPTVTREPFRNMGRLTDLVDSGKLSVDIGLPPMDPAVDRAMICGSPAMLEDTCKLLDDRGFKISP
RMGEAGDYVIERAFVEK

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=236, Percent_Identity=34.3220338983051, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 29176; Mature: 29045

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFNQETVLSVHHWNDSLFSFKTTRDQALRFHNGHFVMIGLEVEGKPLMRAYSIASPNY
CCCCCCCEEEEEEECCCCEEEEECCHHHHHEEECCEEEEEEEEECCCCHHEEEECCCCCH
EEHLEFFSIKVQNGPLTSRLQHLKVGDKLLVSKKPVGTLVLDDLLPGKNLYLFGTGTGLA
HHHEEEEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCEEECCCCCCCCEEEEECCCCHH
PFMSIIQDPDTYERFEKVVLLHGVRQVSELAYADFITRELPNNEFFGDQVREKLIYYPTV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEECCCC
TREPFRNMGRLTDLVDSGKLSVDIGLPPMDPAVDRAMICGSPAMLEDTCKLLDDRGFKIS
CHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEC
PRMGEAGDYVIERAFVEK
CCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SAFNQETVLSVHHWNDSLFSFKTTRDQALRFHNGHFVMIGLEVEGKPLMRAYSIASPNY
CCCCCCEEEEEEECCCCEEEEECCHHHHHEEECCEEEEEEEEECCCCHHEEEECCCCCH
EEHLEFFSIKVQNGPLTSRLQHLKVGDKLLVSKKPVGTLVLDDLLPGKNLYLFGTGTGLA
HHHEEEEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCEEECCCCCCCCEEEEECCCCHH
PFMSIIQDPDTYERFEKVVLLHGVRQVSELAYADFITRELPNNEFFGDQVREKLIYYPTV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEECCCC
TREPFRNMGRLTDLVDSGKLSVDIGLPPMDPAVDRAMICGSPAMLEDTCKLLDDRGFKIS
CHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEC
PRMGEAGDYVIERAFVEK
CCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]