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The map label for this gene is erg3 [H]

Identifier: 187928222

GI number: 187928222

Start: 1208121

End: 1209026

Strand: Reverse

Name: erg3 [H]

Synonym: Rpic_1130

Alternate gene names: 187928222

Gene position: 1209026-1208121 (Counterclockwise)

Preceding gene: 187928228

Following gene: 187928220

Centisome position: 30.67

GC content: 63.02

Gene sequence:

>906_bases
ATGACCCCTGCCAACGCCGCCCCGGGCGCGTCGAGTTTCGACCCCGGCCTGATCCTTCTGGCCTTCGCGCCGGTCTTCCT
GCTGACCATCGGCGCCGAGGCGTGGTACTGGCGCAAGCGCGACCCGTCCGTCTACAGCCTCAAAGACACCGTTTCAAACG
CCTGCCTCGCGCTCATGCACCAGGCGTCGGATGCGTTCTTCCTGTGGCTGATGATCAAGACGGTGTATTCGTGGACGTAC
AGCCACGGCCTGCGCACAGTGCCCGAGACGTGGTGGTCATTCGTGCTGCTCCTGCTGTTGCAGGATTTTCTGTACTACTT
CTTCCACCGCGCCAGCCATCGCGTGCGCTGGATGTGGGCCTCGCATGTGACGCACCACTCGTCGGAAGGCATGAATTTTT
CGACGGCATTCCGCCAGAGCCTGACCTATCCGATTTCCGGCATGTGGCTGTTCTGGATTCCGCTTGCATGGATCGGCTTT
ACGCCGGACTGGGTGATCCTCGCCGTGGGCTTGAATCTCGCGTTCCAGTTTTTCGTCCATACACGGCTGGGGGCGCTGGA
TTCGCGCTACGCCGGCTTCTGGCGCTGGCTGGGGCAATACGTGAATACGCCGTCGGTGCATCGCGTGCACCACGCCAAGA
ACCCGCAGTACATCGACCGCAACTACGCCGGCGTGCTGACCATCTGGGATCGCATGTTCGGCAGCTTCGTGCCGGAGGAG
GACGCCCCCGTTTTCGGCATCACGCGGCAGGTTCACACGCACAACCCGATCACCCTCACCTTCCACGAATGGCGCGACAT
GTGGGCTGATGTGTTCCGCGATCGGGACATTCGCTACCTGTGGAAACCGCCCGAGTGGCGCAGCCCGCGCGCGGCGGTCA
CGGCCGAGGCGATGCCGCTCACATGA

Upstream 100 bases:

>100_bases
GCGTATTGAAGCGAGGAAGGGCTCTAGCCTGCCCCCTTTCGCAGCGCGGGTGTTGGGCGTATACCTGCCAGTTGGAGACG
ACACACATCACAACAATCCA

Downstream 100 bases:

>100_bases
ACGGCGGCCCGAAGCGCGTGGCGACGCGATCGGTGGAATCGAACAGATCGCGCAGCACGGCACTCGTGCACGTCGGCTGC
ACGTACAGGTAGAACGCTAC

Product: fatty acid hydroxylase

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTPANAAPGASSFDPGLILLAFAPVFLLTIGAEAWYWRKRDPSVYSLKDTVSNACLALMHQASDAFFLWLMIKTVYSWTY
SHGLRTVPETWWSFVLLLLLQDFLYYFFHRASHRVRWMWASHVTHHSSEGMNFSTAFRQSLTYPISGMWLFWIPLAWIGF
TPDWVILAVGLNLAFQFFVHTRLGALDSRYAGFWRWLGQYVNTPSVHRVHHAKNPQYIDRNYAGVLTIWDRMFGSFVPEE
DAPVFGITRQVHTHNPITLTFHEWRDMWADVFRDRDIRYLWKPPEWRSPRAAVTAEAMPLT

Sequences:

>Translated_301_residues
MTPANAAPGASSFDPGLILLAFAPVFLLTIGAEAWYWRKRDPSVYSLKDTVSNACLALMHQASDAFFLWLMIKTVYSWTY
SHGLRTVPETWWSFVLLLLLQDFLYYFFHRASHRVRWMWASHVTHHSSEGMNFSTAFRQSLTYPISGMWLFWIPLAWIGF
TPDWVILAVGLNLAFQFFVHTRLGALDSRYAGFWRWLGQYVNTPSVHRVHHAKNPQYIDRNYAGVLTIWDRMFGSFVPEE
DAPVFGITRQVHTHNPITLTFHEWRDMWADVFRDRDIRYLWKPPEWRSPRAAVTAEAMPLT
>Mature_300_residues
TPANAAPGASSFDPGLILLAFAPVFLLTIGAEAWYWRKRDPSVYSLKDTVSNACLALMHQASDAFFLWLMIKTVYSWTYS
HGLRTVPETWWSFVLLLLLQDFLYYFFHRASHRVRWMWASHVTHHSSEGMNFSTAFRQSLTYPISGMWLFWIPLAWIGFT
PDWVILAVGLNLAFQFFVHTRLGALDSRYAGFWRWLGQYVNTPSVHRVHHAKNPQYIDRNYAGVLTIWDRMFGSFVPEED
APVFGITRQVHTHNPITLTFHEWRDMWADVFRDRDIRYLWKPPEWRSPRAAVTAEAMPLT

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=280, Percent_Identity=34.6428571428571, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25144659, Length=242, Percent_Identity=33.4710743801653, Blast_Score=127, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35211; Mature: 35080

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPANAAPGASSFDPGLILLAFAPVFLLTIGAEAWYWRKRDPSVYSLKDTVSNACLALMH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHH
QASDAFFLWLMIKTVYSWTYSHGLRTVPETWWSFVLLLLLQDFLYYFFHRASHRVRWMWA
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
SHVTHHSSEGMNFSTAFRQSLTYPISGMWLFWIPLAWIGFTPDWVILAVGLNLAFQFFVH
HHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TRLGALDSRYAGFWRWLGQYVNTPSVHRVHHAKNPQYIDRNYAGVLTIWDRMFGSFVPEE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
DAPVFGITRQVHTHNPITLTFHEWRDMWADVFRDRDIRYLWKPPEWRSPRAAVTAEAMPL
CCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCCC
T
C
>Mature Secondary Structure 
TPANAAPGASSFDPGLILLAFAPVFLLTIGAEAWYWRKRDPSVYSLKDTVSNACLALMH
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHHHHHHHHHHHH
QASDAFFLWLMIKTVYSWTYSHGLRTVPETWWSFVLLLLLQDFLYYFFHRASHRVRWMWA
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
SHVTHHSSEGMNFSTAFRQSLTYPISGMWLFWIPLAWIGFTPDWVILAVGLNLAFQFFVH
HHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
TRLGALDSRYAGFWRWLGQYVNTPSVHRVHHAKNPQYIDRNYAGVLTIWDRMFGSFVPEE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
DAPVFGITRQVHTHNPITLTFHEWRDMWADVFRDRDIRYLWKPPEWRSPRAAVTAEAMPL
CCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]