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The map label for this gene is rpiA

Identifier: 187928169

GI number: 187928169

Start: 1144856

End: 1145542

Strand: Direct

Name: rpiA

Synonym: Rpic_1076

Alternate gene names: 187928169

Gene position: 1144856-1145542 (Clockwise)

Preceding gene: 187928167

Following gene: 187928172

Centisome position: 29.04

GC content: 65.79

Gene sequence:

>687_bases
ATGACGCAGGATGAACTGAAGGCGCTGGTGGCACAAGCCGCCGCAGACTACGTATTGGCCAACGTGCCCGAGGGCGCCGT
GCTGGGTGTCGGCACCGGCTCGACGGCCAACCTGTTCATCGACGCGATGGCGCCGCACAAGGCACGCTTCGCCGGTGCGG
TGTCCAGCTCCGAGGCTTCGACGCGCCGCCTACAGGGCCACGGCTTTACGGTGCTCGATCTGAACGAAGTCGACGCCATC
CCCGTCTACGTGGACGGCGCTGACGAGATCGACGCCTCGGGCGCCATGATCAAGGGCGGCGGCGGTGCGCTCACGCGCGA
AAAGATCGTTGCCTCGGTCGCCAGCGTGTTTGTCTGCATCGCCGATGGAAGCAAGCTTGTCGAGACGATGGGTGCCTTCC
CGCTGCCGGTGGAAGTGGTGCCCATGGCACGTGCGGCCGTGGCGCGCCAACTGGCTGCGCTGGGCGGTCAGCCGCGCCTG
CGCATGACCAAGGAAGGCCAGATCTACAAGACCGATAACGGCAACGTGATCATCGATGTGGTGGGCCTGCGCATTGCCGA
TCCGAAGGGCCTGGAATCGGTGGTCAACGAGATTCCGGGCGTGGTGACGGTCGGCCTGTTTGCCAAGCGCGGCGCCAATG
TGCTGCTGCTGGGGACCGAAGCGGGCGTGCAGCGTCGCGATTTCTGA

Upstream 100 bases:

>100_bases
AATCGATTGTACTCCGCAGGTCTCGCTCCGCCAGACGGCCGAGAGCTGTCGTGTTGATCCGGTACACTAGCGGGCTTTCC
GATCCGACCGAGTGTTTGCG

Downstream 100 bases:

>100_bases
TCGCTGTTTGCGCATTGTCGAAAAGCTGCTCATGCAAATGGGCAGTTTTTTTTGCGCCCGTTGCGGCACGTTCAATGGCG
TTGCCCAAACAAAAAGCCGT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEASTRRLQGHGFTVLDLNEVDAI
PVYVDGADEIDASGAMIKGGGGALTREKIVASVASVFVCIADGSKLVETMGAFPLPVEVVPMARAAVARQLAALGGQPRL
RMTKEGQIYKTDNGNVIIDVVGLRIADPKGLESVVNEIPGVVTVGLFAKRGANVLLLGTEAGVQRRDF

Sequences:

>Translated_228_residues
MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEASTRRLQGHGFTVLDLNEVDAI
PVYVDGADEIDASGAMIKGGGGALTREKIVASVASVFVCIADGSKLVETMGAFPLPVEVVPMARAAVARQLAALGGQPRL
RMTKEGQIYKTDNGNVIIDVVGLRIADPKGLESVVNEIPGVVTVGLFAKRGANVLLLGTEAGVQRRDF
>Mature_227_residues
TQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEASTRRLQGHGFTVLDLNEVDAIP
VYVDGADEIDASGAMIKGGGGALTREKIVASVASVFVCIADGSKLVETMGAFPLPVEVVPMARAAVARQLAALGGQPRLR
MTKEGQIYKTDNGNVIIDVVGLRIADPKGLESVVNEIPGVVTVGLFAKRGANVLLLGTEAGVQRRDF

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=234, Percent_Identity=36.3247863247863, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=60.7142857142857, Blast_Score=255, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17551758, Length=201, Percent_Identity=36.318407960199, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=214, Percent_Identity=27.1028037383178, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281364072, Length=194, Percent_Identity=35.5670103092784, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_RALPJ (B2U9W6)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898656.1
- ProteinModelPortal:   B2U9W6
- SMR:   B2U9W6
- GeneID:   6288592
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_1076
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23540; Mature: 23409

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEAS
CCHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEECCCCCHHHHCCCCCCCHH
TRRLQGHGFTVLDLNEVDAIPVYVDGADEIDASGAMIKGGGGALTREKIVASVASVFVCI
HHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHEEEE
ADGSKLVETMGAFPLPVEVVPMARAAVARQLAALGGQPRLRMTKEGQIYKTDNGNVIIDV
CCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEEEEE
VGLRIADPKGLESVVNEIPGVVTVGLFAKRGANVLLLGTEAGVQRRDF
EEEEECCCCCHHHHHHHCCCEEEEEHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEAS
CHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCEEEEEECCCCCHHHHCCCCCCCHH
TRRLQGHGFTVLDLNEVDAIPVYVDGADEIDASGAMIKGGGGALTREKIVASVASVFVCI
HHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHEEEE
ADGSKLVETMGAFPLPVEVVPMARAAVARQLAALGGQPRLRMTKEGQIYKTDNGNVIIDV
CCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCEEEEE
VGLRIADPKGLESVVNEIPGVVTVGLFAKRGANVLLLGTEAGVQRRDF
EEEEECCCCCHHHHHHHCCCEEEEEHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA