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The map label for this gene is surE

Identifier: 187928141

GI number: 187928141

Start: 1114241

End: 1114996

Strand: Direct

Name: surE

Synonym: Rpic_1048

Alternate gene names: 187928141

Gene position: 1114241-1114996 (Clockwise)

Preceding gene: 187928139

Following gene: 187928142

Centisome position: 28.26

GC content: 64.95

Gene sequence:

>756_bases
ATGCATATTCTCATTGCCAACGACGACGGATACCTCGCCCCCGGGCTTGCAGCGCTGCATCGCGCGCTGAGCCCCCTCGG
CCGCGTGACGGTGGTCGCACCAGAACAGAACCACAGCGGCGCGTCGAACTCGCTCACGCTGCAGCGTCCGCTTTCGGTGT
TTGAAGCGACCGACGGTGCCCAGAAGGGTTTTCGCTTCGTCAACGGCACGCCGACCGATTGCGTGCACATCGCGCTCACC
GGCATGATCGAAGAGAAACCCGATCTTGTCGTCTCCGGTATCAACCAGGGCCAGAACATGGGTGAAGACGTGCTGTATTC
CGGCACGGTCGCCGCCGCCATCGAAGGTTACCTGTTCGGTATTCCGTCGATTGCGTTTTCGCAGGCCGACAAGGGCTGGG
CGCACCTTGACGCTGCCGAGCGCGTCGCCCGCGAGGTGGTCGAGCGCTATCTGTCCGATCCGCTGGACGGGCCGGTCCTG
CTGAACGTCAACATCCCGAATCTGCCGTACGCCGAGCTGGCAGGTTGGCGTGCGACGCGTCTGGGCAAGCGGCATCAGTC
GCAGCCGGTGATCCGCCAGGCCAATCCACGCGGCGAGCCGATCTTCTGGGTCGGTGCCGCCGGCGATGCGAAAGACGCCA
GCGAGGGCACCGATTTCCACGCCGTTGCGCACGGCTTCGTCTCGCTGACACCGCTGCAGCTCGATCTGACCGATACGGCC
CAACTGCGCACCGTGCGCCGCTGGCAGACGCCATGA

Upstream 100 bases:

>100_bases
GCTGCGATGAAGCGTCCAGCCTGTCGATGCGTATTTTGTAAGCGTGTAGAACGTGTGCCCAAGCACGATTCGCGAACGTT
GCTCGGTTACAATCCGCGCC

Downstream 100 bases:

>100_bases
TCGCCACGGTGGCTCATGTCTGAACGCCCGCGCGATCGGCGCTTCCCGTTGACGCTCGACGCGGTGGTCGAGCGTAAGCC
CGTGGAGCGCCAGCGTGAGA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MHILIANDDGYLAPGLAALHRALSPLGRVTVVAPEQNHSGASNSLTLQRPLSVFEATDGAQKGFRFVNGTPTDCVHIALT
GMIEEKPDLVVSGINQGQNMGEDVLYSGTVAAAIEGYLFGIPSIAFSQADKGWAHLDAAERVAREVVERYLSDPLDGPVL
LNVNIPNLPYAELAGWRATRLGKRHQSQPVIRQANPRGEPIFWVGAAGDAKDASEGTDFHAVAHGFVSLTPLQLDLTDTA
QLRTVRRWQTP

Sequences:

>Translated_251_residues
MHILIANDDGYLAPGLAALHRALSPLGRVTVVAPEQNHSGASNSLTLQRPLSVFEATDGAQKGFRFVNGTPTDCVHIALT
GMIEEKPDLVVSGINQGQNMGEDVLYSGTVAAAIEGYLFGIPSIAFSQADKGWAHLDAAERVAREVVERYLSDPLDGPVL
LNVNIPNLPYAELAGWRATRLGKRHQSQPVIRQANPRGEPIFWVGAAGDAKDASEGTDFHAVAHGFVSLTPLQLDLTDTA
QLRTVRRWQTP
>Mature_251_residues
MHILIANDDGYLAPGLAALHRALSPLGRVTVVAPEQNHSGASNSLTLQRPLSVFEATDGAQKGFRFVNGTPTDCVHIALT
GMIEEKPDLVVSGINQGQNMGEDVLYSGTVAAAIEGYLFGIPSIAFSQADKGWAHLDAAERVAREVVERYLSDPLDGPVL
LNVNIPNLPYAELAGWRATRLGKRHQSQPVIRQANPRGEPIFWVGAAGDAKDASEGTDFHAVAHGFVSLTPLQLDLTDTA
QLRTVRRWQTP

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=248, Percent_Identity=45.5645161290323, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_RALPJ (B2U9T8)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898628.1
- ProteinModelPortal:   B2U9T8
- GeneID:   6287518
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_1048
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27004; Mature: 27004

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILIANDDGYLAPGLAALHRALSPLGRVTVVAPEQNHSGASNSLTLQRPLSVFEATDGA
CEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHCCCCH
QKGFRFVNGTPTDCVHIALTGMIEEKPDLVVSGINQGQNMGEDVLYSGTVAAAIEGYLFG
HHCCEEECCCCCCEEEEEEEHHHCCCCCEEEECCCCCCCCCCHHEECCHHHHHHHHHHHC
IPSIAFSQADKGWAHLDAAERVAREVVERYLSDPLDGPVLLNVNIPNLPYAELAGWRATR
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCCCHHHH
LGKRHQSQPVIRQANPRGEPIFWVGAAGDAKDASEGTDFHAVAHGFVSLTPLQLDLTDTA
HHHHCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHEEECEEEEECCCHH
QLRTVRRWQTP
HHHHHHHCCCC
>Mature Secondary Structure
MHILIANDDGYLAPGLAALHRALSPLGRVTVVAPEQNHSGASNSLTLQRPLSVFEATDGA
CEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHCCCCH
QKGFRFVNGTPTDCVHIALTGMIEEKPDLVVSGINQGQNMGEDVLYSGTVAAAIEGYLFG
HHCCEEECCCCCCEEEEEEEHHHCCCCCEEEECCCCCCCCCCHHEECCHHHHHHHHHHHC
IPSIAFSQADKGWAHLDAAERVAREVVERYLSDPLDGPVLLNVNIPNLPYAELAGWRATR
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCCCHHHH
LGKRHQSQPVIRQANPRGEPIFWVGAAGDAKDASEGTDFHAVAHGFVSLTPLQLDLTDTA
HHHHCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHEEECEEEEECCCHH
QLRTVRRWQTP
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA