Click here to switch to the map view.

The map label for this gene is tcp [H]

Identifier: 187928089

GI number: 187928089

Start: 1054582

End: 1056387

Strand: Direct

Name: tcp [H]

Synonym: Rpic_0996

Alternate gene names: 187928089

Gene position: 1054582-1056387 (Clockwise)

Preceding gene: 187928088

Following gene: 187928092

Centisome position: 26.75

GC content: 65.12

Gene sequence:

>1806_bases
ATGGACCGCATTTTGAAGAACACCAGCGTGCGCGCTGGCCTGCTGGCGATTCTGATCACCTTTGCACTGATGATCGTGGT
CGGCGCGGCGGTGGGTGTGCTGGCCTTGCGCACCACCAACGCGGCCACCGAGCGCGTGCATCAGATTTCCGACCGCAGCA
TGCTGTTGAACGACGCGTACAAGGACATGCAGCGCGCGCGCACCGGCATGTCGCGCCTGTACAGCGTCCTGCGCGAGAAC
ATGGATGGCGCTGCCAAGACGACAGCGCTTGCCAGCTCGGAGAAGGGCCTGAAGAAGTCCATCGAACAGGTCGAAGCCTT
CAAGAATGCGCCGCCCATCGAAGGTGTGGACGAGTCGCTGCGCCAGGCGATCGTGCAGGCCGCACAGACGCACATCGAAG
CCGTGCAGCGTGGCATGGCGGCCTTGCGCGCAGGTGATGCCTCAGCTTATGCCCCGATCAACTACAAGGACGTGACCGAT
ACCGGTGCAGCGTGGTCGGTGCAAATCGAGAATTTCCAGCAGCTCGTCAAGAAGCTGGCCAAGGACGAGGCCGACAGCGG
CCGCGCGCGCTACGAAACGATCCTCAAGTTCGTGGCGCTCGGTATTGCCATGGCGCTCGCGTTGATCGTGGCGGTGTTCT
ACGGGCTCAAGGCCTTCGTGATCACGCCGCTCAACGAAGCCGTGACCGTGCTGAGTCGCGTGGCTGAAGGCGATTTGGCC
GTGCATGTCAAGACGGGTGGCCGCAATGAACTGGGCCGCCTGCTGGCTGCCGTGGGTCGCATGCGCGAAAGCCTGGTGAA
CACCGTTCGCCAGGTGCGTAACAGCTCGGATTCGGTCAACACCGGCGCGCACGAAATCGCCAGCGGCAACCTCGATCTGT
CTTCGCGTACCGAGCAGCAATCCGCCTCGCTCGAGAAGACGGCTGCCAGCATGGAGCAGATGACCTCCACCGTCACCAAC
AACTCCGAGAACGCCCGCCAGGCCAGCGCGCTGGCGTCGAATGCGGCAGACCTGGCTTCGCGTGGCGGCGATGTAGTGCG
TGGCGTGGTGGCCACCATGGACGACATCAGCGCGGGCTCGCGCAAGATGGCCGACATCATCGGCGTGATTGACGGCATTG
CGTTCCAGACCAACATCCTGGCGCTCAACGCTGCCGTGGAAGCTGCCCGCGCCGGCGAGCAGGGCCGCGGCTTTGCCGTG
GTGGCAGGCGAAGTGCGCGCGCTGGCTCAACGCAGTGCTGCTGCGGCCAAGGAAATCAAGACGTTGATCGACGATTCGGT
GTCGCGCGTGCAAGCGGGCCACACGCAGGTGGCGCAGGCCGGCGAGACTATCACCGAGACCGTGGAGGCCGTGCGCCGCG
TCGCCAACATCGTTGAAGACATTGCCTCCGCATCGGTCGAGCAGACGCAGGGCATCCTGCAGATCGGCCAGGCCGTGACG
GAAATGGAGCAGGTGACGCAGCAGAACGCCGCGCTGGTCGAACAGGCGGCCGCCGCCGCGCAATCGCTGGAAGAGCAGGC
GCAGAACCTTACGCAGGTCGTGTCGCAGTTCCGGCTGGATGGGGCAGGGAACGCCGCGATGGCTGTGCGCAAGCCCGAGA
AGGTTTCCAAGCCGGTGGCCAAGGCCGCTGCACAGCCGGTCAGCGCGGCCAAGCCGGCACGGGCGGCGCTGCGCAAGCGC
GAACCGAAGATCGCAGTTCAGCCGGTGGCTTCGGTGCCGGTCGCACCTGCCGCTGCCGCCCGGAAGCAACAGCAACCTCT
GGCCGTAGCCGGTGGCAGTTCCGACGCGGATTGGGAAACGTTCTAA

Upstream 100 bases:

>100_bases
CAACGCTGACTGGGAAACGTTCTGACCCACGATTGACCTTCACCTCGTTGACCCCGCACACCGCAAGCATGGGTTTGCCT
GCCGGGACCCCGGAGACAAG

Downstream 100 bases:

>100_bases
ACGGTTGAGAACTCAGGCTTCGAGCGCTGGGCCATCGATGCGTCTGGCCCAGCTTTCCACCTCGCCACGTGCGAGGCGGC
CTTCCACCAGCTTGCGCCAT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MDRILKNTSVRAGLLAILITFALMIVVGAAVGVLALRTTNAATERVHQISDRSMLLNDAYKDMQRARTGMSRLYSVLREN
MDGAAKTTALASSEKGLKKSIEQVEAFKNAPPIEGVDESLRQAIVQAAQTHIEAVQRGMAALRAGDASAYAPINYKDVTD
TGAAWSVQIENFQQLVKKLAKDEADSGRARYETILKFVALGIAMALALIVAVFYGLKAFVITPLNEAVTVLSRVAEGDLA
VHVKTGGRNELGRLLAAVGRMRESLVNTVRQVRNSSDSVNTGAHEIASGNLDLSSRTEQQSASLEKTAASMEQMTSTVTN
NSENARQASALASNAADLASRGGDVVRGVVATMDDISAGSRKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRALAQRSAAAAKEIKTLIDDSVSRVQAGHTQVAQAGETITETVEAVRRVANIVEDIASASVEQTQGILQIGQAVT
EMEQVTQQNAALVEQAAAAAQSLEEQAQNLTQVVSQFRLDGAGNAAMAVRKPEKVSKPVAKAAAQPVSAAKPARAALRKR
EPKIAVQPVASVPVAPAAAARKQQQPLAVAGGSSDADWETF

Sequences:

>Translated_601_residues
MDRILKNTSVRAGLLAILITFALMIVVGAAVGVLALRTTNAATERVHQISDRSMLLNDAYKDMQRARTGMSRLYSVLREN
MDGAAKTTALASSEKGLKKSIEQVEAFKNAPPIEGVDESLRQAIVQAAQTHIEAVQRGMAALRAGDASAYAPINYKDVTD
TGAAWSVQIENFQQLVKKLAKDEADSGRARYETILKFVALGIAMALALIVAVFYGLKAFVITPLNEAVTVLSRVAEGDLA
VHVKTGGRNELGRLLAAVGRMRESLVNTVRQVRNSSDSVNTGAHEIASGNLDLSSRTEQQSASLEKTAASMEQMTSTVTN
NSENARQASALASNAADLASRGGDVVRGVVATMDDISAGSRKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRALAQRSAAAAKEIKTLIDDSVSRVQAGHTQVAQAGETITETVEAVRRVANIVEDIASASVEQTQGILQIGQAVT
EMEQVTQQNAALVEQAAAAAQSLEEQAQNLTQVVSQFRLDGAGNAAMAVRKPEKVSKPVAKAAAQPVSAAKPARAALRKR
EPKIAVQPVASVPVAPAAAARKQQQPLAVAGGSSDADWETF
>Mature_601_residues
MDRILKNTSVRAGLLAILITFALMIVVGAAVGVLALRTTNAATERVHQISDRSMLLNDAYKDMQRARTGMSRLYSVLREN
MDGAAKTTALASSEKGLKKSIEQVEAFKNAPPIEGVDESLRQAIVQAAQTHIEAVQRGMAALRAGDASAYAPINYKDVTD
TGAAWSVQIENFQQLVKKLAKDEADSGRARYETILKFVALGIAMALALIVAVFYGLKAFVITPLNEAVTVLSRVAEGDLA
VHVKTGGRNELGRLLAAVGRMRESLVNTVRQVRNSSDSVNTGAHEIASGNLDLSSRTEQQSASLEKTAASMEQMTSTVTN
NSENARQASALASNAADLASRGGDVVRGVVATMDDISAGSRKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRALAQRSAAAAKEIKTLIDDSVSRVQAGHTQVAQAGETITETVEAVRRVANIVEDIASASVEQTQGILQIGQAVT
EMEQVTQQNAALVEQAAAAAQSLEEQAQNLTQVVSQFRLDGAGNAAMAVRKPEKVSKPVAKAAAQPVSAAKPARAALRKR
EPKIAVQPVASVPVAPAAAARKQQQPLAVAGGSSDADWETF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=552, Percent_Identity=43.4782608695652, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI2367378, Length=527, Percent_Identity=44.4022770398482, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1787690, Length=489, Percent_Identity=42.9447852760736, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI1788194, Length=357, Percent_Identity=50.7002801120448, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1789453, Length=343, Percent_Identity=38.4839650145773, Blast_Score=201, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 63160; Mature: 63160

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRILKNTSVRAGLLAILITFALMIVVGAAVGVLALRTTNAATERVHQISDRSMLLNDAY
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KDMQRARTGMSRLYSVLRENMDGAAKTTALASSEKGLKKSIEQVEAFKNAPPIEGVDESL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RQAIVQAAQTHIEAVQRGMAALRAGDASAYAPINYKDVTDTGAAWSVQIENFQQLVKKLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
KDEADSGRARYETILKFVALGIAMALALIVAVFYGLKAFVITPLNEAVTVLSRVAEGDLA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEE
VHVKTGGRNELGRLLAAVGRMRESLVNTVRQVRNSSDSVNTGAHEIASGNLDLSSRTEQQ
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHH
SASLEKTAASMEQMTSTVTNNSENARQASALASNAADLASRGGDVVRGVVATMDDISAGS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
RKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSAAAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
TLIDDSVSRVQAGHTQVAQAGETITETVEAVRRVANIVEDIASASVEQTQGILQIGQAVT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMEQVTQQNAALVEQAAAAAQSLEEQAQNLTQVVSQFRLDGAGNAAMAVRKPEKVSKPVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
KAAAQPVSAAKPARAALRKREPKIAVQPVASVPVAPAAAARKQQQPLAVAGGSSDADWET
HHHCCCCHHCCHHHHHHHHCCCCEEECCHHCCCCCCHHHHHHCCCCCEEECCCCCCCCCC
F
C
>Mature Secondary Structure
MDRILKNTSVRAGLLAILITFALMIVVGAAVGVLALRTTNAATERVHQISDRSMLLNDAY
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KDMQRARTGMSRLYSVLRENMDGAAKTTALASSEKGLKKSIEQVEAFKNAPPIEGVDESL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RQAIVQAAQTHIEAVQRGMAALRAGDASAYAPINYKDVTDTGAAWSVQIENFQQLVKKLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
KDEADSGRARYETILKFVALGIAMALALIVAVFYGLKAFVITPLNEAVTVLSRVAEGDLA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEE
VHVKTGGRNELGRLLAAVGRMRESLVNTVRQVRNSSDSVNTGAHEIASGNLDLSSRTEQQ
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHH
SASLEKTAASMEQMTSTVTNNSENARQASALASNAADLASRGGDVVRGVVATMDDISAGS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCH
RKMADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAQRSAAAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
TLIDDSVSRVQAGHTQVAQAGETITETVEAVRRVANIVEDIASASVEQTQGILQIGQAVT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMEQVTQQNAALVEQAAAAAQSLEEQAQNLTQVVSQFRLDGAGNAAMAVRKPEKVSKPVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHH
KAAAQPVSAAKPARAALRKREPKIAVQPVASVPVAPAAAARKQQQPLAVAGGSSDADWET
HHHCCCCHHCCHHHHHHHHCCCCEEECCHHCCCCCCHHHHHHCCCCCEEECCCCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]