Click here to switch to the map view.

The map label for this gene is 187928059

Identifier: 187928059

GI number: 187928059

Start: 1024429

End: 1025274

Strand: Direct

Name: 187928059

Synonym: Rpic_0966

Alternate gene names: NA

Gene position: 1024429-1025274 (Clockwise)

Preceding gene: 187928058

Following gene: 187928060

Centisome position: 25.98

GC content: 65.48

Gene sequence:

>846_bases
GTGAAATACCAAATTCGACATACGACGGTCTACCGTTATGCCGAGCCGCTGCGCCACAGCGTGCATGAGCTGCGGCTGAC
GCCTCGCAGCGGCGAGCTGCAGCAGGTGGAGAGCTGGCAGATCCACGCGCCTGGCAACCTCACGCGCGCCACCGACGGTT
TCGGCAACATCGTCCACCACTTCACTCTCGGCAACCGTACGGAAGACGTCATCATCGACGCGCGCGGCATTGTCGAAGCG
TTTCCTGCGGGCTCGCCTGGCAGCCAACGGTTTGTCGAAGCACGCGAGCAGGGGCGCTATCGCGTTTCGCCGCTGTATTT
TCTGAGCGCCACGCCGCTGACTTCCGCGCCCGCCGAGATGATCGACTTTGCGCGCGAGCATGCACTGGTGCACGGCGACG
CAGAATCTGCCGTGCGCCTGGCGCAAGCCATTGCCACGCGTGTGCGCTACAAGCCGAACACCACTCACGTCGGCACGGCC
GCTGCGGAGGCGTTTGGCCTGGGCACGGGCGTATGCCAGGACCAGGCGCAGGTGATGGTCGCGTGCTGCCGGGCACTGGG
CGTGCCGGCGCGCTATGTCAGCGGCTATTTCCAAGCCGTGGGCGAGGAAGACCTTGCCAGTCATGCCTGGGCCGACGTCT
GCCTCGATGCCGAATCCCACACGTGGTGCAGCATCGACGTCACCCACCAATGCTTTACCGATGCGCGCCATATCCGGTTG
GCGGTCGGGCGTGATTACCAGTCGGCTGCGCCGGTTCGCGGCGTGCGGCAGGGCGGGGGTGCTGAGACGCTGGATGTCAG
CATCTCCATCGAGCCGCTGCCCGCCGAGGCTGCGCAAGTGAATTGA

Upstream 100 bases:

>100_bases
GGCATCAGCCAGGATTTCCTGGTGCCGCTCGAGGTCGCATGACCCTGCAGGGCATTGTGCATACATCGGGGCGCCGCTTT
CGGGCGGCGCCCGTGTCATC

Downstream 100 bases:

>100_bases
GCATCTCTTCCAAGCGCGCGGATGGGTTCTGATCGCCGCGCTAGAATGCCCTCAACCACCGTTTCCGTTTGTTGTTTCGC
CCATGACTTATTGCGTCGCC

Product: transglutaminase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKYQIRHTTVYRYAEPLRHSVHELRLTPRSGELQQVESWQIHAPGNLTRATDGFGNIVHHFTLGNRTEDVIIDARGIVEA
FPAGSPGSQRFVEAREQGRYRVSPLYFLSATPLTSAPAEMIDFAREHALVHGDAESAVRLAQAIATRVRYKPNTTHVGTA
AAEAFGLGTGVCQDQAQVMVACCRALGVPARYVSGYFQAVGEEDLASHAWADVCLDAESHTWCSIDVTHQCFTDARHIRL
AVGRDYQSAAPVRGVRQGGGAETLDVSISIEPLPAEAAQVN

Sequences:

>Translated_281_residues
MKYQIRHTTVYRYAEPLRHSVHELRLTPRSGELQQVESWQIHAPGNLTRATDGFGNIVHHFTLGNRTEDVIIDARGIVEA
FPAGSPGSQRFVEAREQGRYRVSPLYFLSATPLTSAPAEMIDFAREHALVHGDAESAVRLAQAIATRVRYKPNTTHVGTA
AAEAFGLGTGVCQDQAQVMVACCRALGVPARYVSGYFQAVGEEDLASHAWADVCLDAESHTWCSIDVTHQCFTDARHIRL
AVGRDYQSAAPVRGVRQGGGAETLDVSISIEPLPAEAAQVN
>Mature_281_residues
MKYQIRHTTVYRYAEPLRHSVHELRLTPRSGELQQVESWQIHAPGNLTRATDGFGNIVHHFTLGNRTEDVIIDARGIVEA
FPAGSPGSQRFVEAREQGRYRVSPLYFLSATPLTSAPAEMIDFAREHALVHGDAESAVRLAQAIATRVRYKPNTTHVGTA
AAEAFGLGTGVCQDQAQVMVACCRALGVPARYVSGYFQAVGEEDLASHAWADVCLDAESHTWCSIDVTHQCFTDARHIRL
AVGRDYQSAAPVRGVRQGGGAETLDVSISIEPLPAEAAQVN

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0607 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013589
- InterPro:   IPR002931 [H]

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core [H]

EC number: NA

Molecular weight: Translated: 30632; Mature: 30632

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQIRHTTVYRYAEPLRHSVHELRLTPRSGELQQVESWQIHAPGNLTRATDGFGNIVHH
CCEEEEHHHHHHHHHHHHHHHHHEEECCCCCCCHHHCCEEEECCCCCCCCCCCHHHHEEE
FTLGNRTEDVIIDARGIVEAFPAGSPGSQRFVEAREQGRYRVSPLYFLSATPLTSAPAEM
EECCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHCCCEEECEEEEEECCCCCCCCHHH
IDFAREHALVHGDAESAVRLAQAIATRVRYKPNTTHVGTAAAEAFGLGTGVCQDQAQVMV
HHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHH
ACCRALGVPARYVSGYFQAVGEEDLASHAWADVCLDAESHTWCSIDVTHQCFTDARHIRL
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCEEEEECCHHHHHCCCEEEE
AVGRDYQSAAPVRGVRQGGGAETLDVSISIEPLPAEAAQVN
EECCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKYQIRHTTVYRYAEPLRHSVHELRLTPRSGELQQVESWQIHAPGNLTRATDGFGNIVHH
CCEEEEHHHHHHHHHHHHHHHHHEEECCCCCCCHHHCCEEEECCCCCCCCCCCHHHHEEE
FTLGNRTEDVIIDARGIVEAFPAGSPGSQRFVEAREQGRYRVSPLYFLSATPLTSAPAEM
EECCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHCCCEEECEEEEEECCCCCCCCHHH
IDFAREHALVHGDAESAVRLAQAIATRVRYKPNTTHVGTAAAEAFGLGTGVCQDQAQVMV
HHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHH
ACCRALGVPARYVSGYFQAVGEEDLASHAWADVCLDAESHTWCSIDVTHQCFTDARHIRL
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCEEEEECCHHHHHCCCEEEE
AVGRDYQSAAPVRGVRQGGGAETLDVSISIEPLPAEAAQVN
EECCCCCCCCCCHHHHCCCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]