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The map label for this gene is hscB [H]

Identifier: 187927983

GI number: 187927983

Start: 941049

End: 941588

Strand: Direct

Name: hscB [H]

Synonym: Rpic_0888

Alternate gene names: 187927983

Gene position: 941049-941588 (Clockwise)

Preceding gene: 187927982

Following gene: 187927984

Centisome position: 23.87

GC content: 61.48

Gene sequence:

>540_bases
ATGAATTCCGGCTTGTCAGCGAACACGACGCATTTTTCTCTCTTCGGTCTGCCCGAGCACTTCGAGGTCGACGACGACGC
GCTGAACGCTGCGTATCGCACCGTGCAGTCGCAGGCGCATCCGGATCGTTATGCCCATGCGGGCGATGCCGAACGCCGCG
TCGCCATGCAGTGGGCCACACGTGCGAACGAGGCGTATCAGACGCTGCGTGACCCGCTCAAACGGGCGACGTATCTGCTG
CACCTGCGCGGTATCGACGTGCAGGCAGAGAACAACACGGCCATGCCGCCCGCGTTTCTGATGCAGCAAATGGAATGGCG
CGAAGCCTTGGGCGACGCCAAGGCGGAGCGCAACGTCGATGCGCTGGATGATTTGCTTGGCATGCTGCGCAAGGAAAAAC
GCACGCGCTATCAGGCGCTGTCCGGTCTGCTCAATAGCGATGGCAACACCGCAGCAGCAGCCGATGCCGTGCGCCAATTG
ATGTTCATCGAAAAGATCGAACGCGACACCGCCGAGGCCATCGACCGGCTGGAAGACTAG

Upstream 100 bases:

>100_bases
AGATGGGCGTGGTGGTCGAGTGCCTGAAGTGCGATCGGGGTGAGCCGGTCGAATAAGAAACACGAAGGAACACTAGGCGG
CGCAGCCGCTTTTTTTATTC

Downstream 100 bases:

>100_bases
AACCCAGAATTTGCGACAATGTTAGGTTTGCCCCGGCAGGCAGCCCATCCGCGCAATCGAGACATCCCCATGGCTTTACT
GCAGATTTCCGAACCTGGCG

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNSGLSANTTHFSLFGLPEHFEVDDDALNAAYRTVQSQAHPDRYAHAGDAERRVAMQWATRANEAYQTLRDPLKRATYLL
HLRGIDVQAENNTAMPPAFLMQQMEWREALGDAKAERNVDALDDLLGMLRKEKRTRYQALSGLLNSDGNTAAAADAVRQL
MFIEKIERDTAEAIDRLED

Sequences:

>Translated_179_residues
MNSGLSANTTHFSLFGLPEHFEVDDDALNAAYRTVQSQAHPDRYAHAGDAERRVAMQWATRANEAYQTLRDPLKRATYLL
HLRGIDVQAENNTAMPPAFLMQQMEWREALGDAKAERNVDALDDLLGMLRKEKRTRYQALSGLLNSDGNTAAAADAVRQL
MFIEKIERDTAEAIDRLED
>Mature_179_residues
MNSGLSANTTHFSLFGLPEHFEVDDDALNAAYRTVQSQAHPDRYAHAGDAERRVAMQWATRANEAYQTLRDPLKRATYLL
HLRGIDVQAENNTAMPPAFLMQQMEWREALGDAKAERNVDALDDLLGMLRKEKRTRYQALSGLLNSDGNTAAAADAVRQL
MFIEKIERDTAEAIDRLED

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=122, Percent_Identity=31.9672131147541, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1788876, Length=165, Percent_Identity=38.7878787878788, Blast_Score=117, Evalue=4e-28,
Organism=Drosophila melanogaster, GI161084223, Length=146, Percent_Identity=31.5068493150685, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20163; Mature: 20163

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSGLSANTTHFSLFGLPEHFEVDDDALNAAYRTVQSQAHPDRYAHAGDAERRVAMQWAT
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHH
RANEAYQTLRDPLKRATYLLHLRGIDVQAENNTAMPPAFLMQQMEWREALGDAKAERNVD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ALDDLLGMLRKEKRTRYQALSGLLNSDGNTAAAADAVRQLMFIEKIERDTAEAIDRLED
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSGLSANTTHFSLFGLPEHFEVDDDALNAAYRTVQSQAHPDRYAHAGDAERRVAMQWAT
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHH
RANEAYQTLRDPLKRATYLLHLRGIDVQAENNTAMPPAFLMQQMEWREALGDAKAERNVD
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ALDDLLGMLRKEKRTRYQALSGLLNSDGNTAAAADAVRQLMFIEKIERDTAEAIDRLED
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]