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The map label for this gene is yhfN [H]

Identifier: 187927907

GI number: 187927907

Start: 855878

End: 857137

Strand: Reverse

Name: yhfN [H]

Synonym: Rpic_0812

Alternate gene names: 187927907

Gene position: 857137-855878 (Counterclockwise)

Preceding gene: 187927909

Following gene: 187927906

Centisome position: 21.74

GC content: 63.17

Gene sequence:

>1260_bases
ATGCCCGCCTTTACCGCTGTCTTCCTGATCGCCCTTGTATTGATGTCCGCCACGCGCCTGTGGCTGGCCGCGCGGCAAGT
CCGTCACGTGGCGCGTCACCGCGATGCCGTGCCTGCGCAGTTCGCCGAGTCGATCACACTGGACATGCACCGCAAGGCCG
CCGACTACACCATCGCCCGCACCCGTCTGGCGATGCTCGAAGTACCGGTTCAAGCCGCCCTACTGATCGCGCTGACGCTG
CTCGGGGGGCTGAACTGGATCAACCAGGCTTGGCTGGGCGTGTTCGGCCCCGGTTACGCGTATGGCGTGGCGCTGATCGC
GTCGGTCATCGCGATCAGCAGCGTGGTCGAATTGCCGTTTTCGCTGTACGCCCAGTTCGTCGTCGAAGAGCGTTTTGGGT
TCAACCGCATGACGTTCAAGCTGTGGCTGGCCGACAACCTCAAGGGCCTGGCCATCGGAACCGTGCTGGGTCTGCCGCTG
CTGCTGGCAGTGCTCTGGCTGATGGACAAGATGGGCGCGTACTGGTGGCTGTACACCTGGATCGTGTGGATGGCGTTCAT
GCTGTTTGTTCAGGCCATCTACCCCAACGTCATCGCACCGCTCTACAACAAGTTCACCCCGCTGCAGGACGAGGAAATGC
GCTCGCGTATCGAAAGCCTGCTCAAGCGCTGCGGCTTCGCCAGCAAGGGCCTGTTCGTGATGGACGGCAGCCGCCGCAGC
GCCCACGGCAACGCCTACTTCAGCGGCTTTGGTGCGACCAAGCGCATCGTCTTCTTCGACACGCTGCTCGCCCGCCTGAA
TCCGTCCGAAATGGAAGCCGTGCTCGCGCATGAGCTGGGCCATTTCAAGCGCCATCACATCACCAAGCGCATCGCCGTGA
CGTTCGTGCTGAGCCTGGGTGCTCTGGCGCTGCTCGGCTGGCTGATGACGCGCACGTGGTTTTACCTGGGCCTTGGCGTC
GCTCCGAACCTGTTCTCCGACAACCACGCGCTGGCGCTGATGCTGTTTTTCCTAGTGCTGCCGGTGTTCACGTTCTTCGT
CTCGCCGCTGGCGAGCCTGTCGTCTCGCAAGGACGAGTACGAAGCGGACGCCTTTGCCGCCGAGCACGCCGACGCCAATC
AACTTGTCTCGGCGCTGGTCAAGCTGTTCCAGGACAACGCATCGACGCTCACGCCGGACCCGGTCTACTCAACGTTCTAC
TATTCGCACCCGACTGCATCGCAGCGCGTGGAGCGCCTCGTGCAGGCTCGCGCGGCATGA

Upstream 100 bases:

>100_bases
GGACAGGGAAACAGGGGTACTCGCGGGGGTGCTCACTCAAGGGCCTTGAGAAAATGACTGAAGGCTATAATTTTCGCATA
TCTGATAGGTGTTTCCCCAC

Downstream 100 bases:

>100_bases
CGCGCGGCAAACCGGGCCGCGCCCATAAGCAGGCTGCCACTGGCGAACACGGGCTCGTCATCGCCGCGCACGGGCGCCAT
TACCTGGTCGAACGCGACGG

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MPAFTAVFLIALVLMSATRLWLAARQVRHVARHRDAVPAQFAESITLDMHRKAADYTIARTRLAMLEVPVQAALLIALTL
LGGLNWINQAWLGVFGPGYAYGVALIASVIAISSVVELPFSLYAQFVVEERFGFNRMTFKLWLADNLKGLAIGTVLGLPL
LLAVLWLMDKMGAYWWLYTWIVWMAFMLFVQAIYPNVIAPLYNKFTPLQDEEMRSRIESLLKRCGFASKGLFVMDGSRRS
AHGNAYFSGFGATKRIVFFDTLLARLNPSEMEAVLAHELGHFKRHHITKRIAVTFVLSLGALALLGWLMTRTWFYLGLGV
APNLFSDNHALALMLFFLVLPVFTFFVSPLASLSSRKDEYEADAFAAEHADANQLVSALVKLFQDNASTLTPDPVYSTFY
YSHPTASQRVERLVQARAA

Sequences:

>Translated_419_residues
MPAFTAVFLIALVLMSATRLWLAARQVRHVARHRDAVPAQFAESITLDMHRKAADYTIARTRLAMLEVPVQAALLIALTL
LGGLNWINQAWLGVFGPGYAYGVALIASVIAISSVVELPFSLYAQFVVEERFGFNRMTFKLWLADNLKGLAIGTVLGLPL
LLAVLWLMDKMGAYWWLYTWIVWMAFMLFVQAIYPNVIAPLYNKFTPLQDEEMRSRIESLLKRCGFASKGLFVMDGSRRS
AHGNAYFSGFGATKRIVFFDTLLARLNPSEMEAVLAHELGHFKRHHITKRIAVTFVLSLGALALLGWLMTRTWFYLGLGV
APNLFSDNHALALMLFFLVLPVFTFFVSPLASLSSRKDEYEADAFAAEHADANQLVSALVKLFQDNASTLTPDPVYSTFY
YSHPTASQRVERLVQARAA
>Mature_418_residues
PAFTAVFLIALVLMSATRLWLAARQVRHVARHRDAVPAQFAESITLDMHRKAADYTIARTRLAMLEVPVQAALLIALTLL
GGLNWINQAWLGVFGPGYAYGVALIASVIAISSVVELPFSLYAQFVVEERFGFNRMTFKLWLADNLKGLAIGTVLGLPLL
LAVLWLMDKMGAYWWLYTWIVWMAFMLFVQAIYPNVIAPLYNKFTPLQDEEMRSRIESLLKRCGFASKGLFVMDGSRRSA
HGNAYFSGFGATKRIVFFDTLLARLNPSEMEAVLAHELGHFKRHHITKRIAVTFVLSLGALALLGWLMTRTWFYLGLGVA
PNLFSDNHALALMLFFLVLPVFTFFVSPLASLSSRKDEYEADAFAAEHADANQLVSALVKLFQDNASTLTPDPVYSTFYY
SHPTASQRVERLVQARAA

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=470, Percent_Identity=29.7872340425532, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17505484, Length=432, Percent_Identity=30.787037037037, Blast_Score=190, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6322577, Length=307, Percent_Identity=37.4592833876222, Blast_Score=205, Evalue=1e-53,
Organism=Drosophila melanogaster, GI19922414, Length=443, Percent_Identity=31.8284424379233, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24654305, Length=285, Percent_Identity=27.3684210526316, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI78707252, Length=311, Percent_Identity=26.3665594855305, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI78707254, Length=311, Percent_Identity=26.3665594855305, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 46929; Mature: 46797

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFTAVFLIALVLMSATRLWLAARQVRHVARHRDAVPAQFAESITLDMHRKAADYTIAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRLAMLEVPVQAALLIALTLLGGLNWINQAWLGVFGPGYAYGVALIASVIAISSVVELPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SLYAQFVVEERFGFNRMTFKLWLADNLKGLAIGTVLGLPLLLAVLWLMDKMGAYWWLYTW
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWMAFMLFVQAIYPNVIAPLYNKFTPLQDEEMRSRIESLLKRCGFASKGLFVMDGSRRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
AHGNAYFSGFGATKRIVFFDTLLARLNPSEMEAVLAHELGHFKRHHITKRIAVTFVLSLG
CCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALALLGWLMTRTWFYLGLGVAPNLFSDNHALALMLFFLVLPVFTFFVSPLASLSSRKDEY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EADAFAAEHADANQLVSALVKLFQDNASTLTPDPVYSTFYYSHPTASQRVERLVQARAA
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAFTAVFLIALVLMSATRLWLAARQVRHVARHRDAVPAQFAESITLDMHRKAADYTIAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TRLAMLEVPVQAALLIALTLLGGLNWINQAWLGVFGPGYAYGVALIASVIAISSVVELPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SLYAQFVVEERFGFNRMTFKLWLADNLKGLAIGTVLGLPLLLAVLWLMDKMGAYWWLYTW
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWMAFMLFVQAIYPNVIAPLYNKFTPLQDEEMRSRIESLLKRCGFASKGLFVMDGSRRS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
AHGNAYFSGFGATKRIVFFDTLLARLNPSEMEAVLAHELGHFKRHHITKRIAVTFVLSLG
CCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALALLGWLMTRTWFYLGLGVAPNLFSDNHALALMLFFLVLPVFTFFVSPLASLSSRKDEY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
EADAFAAEHADANQLVSALVKLFQDNASTLTPDPVYSTFYYSHPTASQRVERLVQARAA
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]