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The map label for this gene is fbp [H]

Identifier: 187927826

GI number: 187927826

Start: 765605

End: 765958

Strand: Reverse

Name: fbp [H]

Synonym: Rpic_0730

Alternate gene names: 187927826

Gene position: 765958-765605 (Counterclockwise)

Preceding gene: 187927827

Following gene: 187927825

Centisome position: 19.43

GC content: 63.84

Gene sequence:

>354_bases
ATGACCATCGAAACCACCGCAAGCGGCCTGCAATACGAAGATGTCGTCGTCGGCGACGGCGCGCAAGCCACGGCTGGCCA
GTACGTCACCGTGCACTACACCGGCTGGCTCTACGAAAACGGCCAGGCCGGCAAGAAGTTCGATTCCAGCAAGGACCGTA
ACGACCCGTTCGCTTTTCACCTGGGCGGCGGCATGGTCATCAAGGGCTGGGACGAAGGCGTGCAAGGCATGAAGGTCGGC
GGCACGCGCAAGCTGATCATCCCGGCAGCCCTGGGCTACGGCGCACGCGGCGCGGGCGGCGTGATCCCCCCGAACGCAAC
GTTGCTTTTTGAGGTCGACCTGCTGGAAGTCTGA

Upstream 100 bases:

>100_bases
ACGACGCGGACAACGTCCACGTCCAGCTCGAAACACTCAAGGCCGCAACCGCTGCCTGAGCCTGTTCCCTTATCACCCAC
GCCACTCCACGAGGCTCATC

Downstream 100 bases:

>100_bases
TCCTGCGCTAGAATCCGCCCCGGCTCGCGATGCGTCACACGGTGCATCACGAGCCACCTCCCCCGGCGGGGTGGCAGAGT
GGTCAATGCTGCGGCTTGCA

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MTIETTASGLQYEDVVVGDGAQATAGQYVTVHYTGWLYENGQAGKKFDSSKDRNDPFAFHLGGGMVIKGWDEGVQGMKVG
GTRKLIIPAALGYGARGAGGVIPPNATLLFEVDLLEV

Sequences:

>Translated_117_residues
MTIETTASGLQYEDVVVGDGAQATAGQYVTVHYTGWLYENGQAGKKFDSSKDRNDPFAFHLGGGMVIKGWDEGVQGMKVG
GTRKLIIPAALGYGARGAGGVIPPNATLLFEVDLLEV
>Mature_116_residues
TIETTASGLQYEDVVVGDGAQATAGQYVTVHYTGWLYENGQAGKKFDSSKDRNDPFAFHLGGGMVIKGWDEGVQGMKVGG
TRKLIIPAALGYGARGAGGVIPPNATLLFEVDLLEV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=110, Percent_Identity=51.8181818181818, Blast_Score=105, Evalue=7e-24,
Organism=Homo sapiens, GI4503725, Length=110, Percent_Identity=51.8181818181818, Blast_Score=105, Evalue=7e-24,
Organism=Homo sapiens, GI4758380, Length=110, Percent_Identity=50, Blast_Score=103, Evalue=4e-23,
Organism=Homo sapiens, GI206725530, Length=96, Percent_Identity=52.0833333333333, Blast_Score=97, Evalue=2e-21,
Organism=Homo sapiens, GI17149844, Length=96, Percent_Identity=52.0833333333333, Blast_Score=97, Evalue=2e-21,
Organism=Homo sapiens, GI17149842, Length=96, Percent_Identity=52.0833333333333, Blast_Score=97, Evalue=2e-21,
Organism=Homo sapiens, GI4503729, Length=91, Percent_Identity=51.6483516483517, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=40.5660377358491, Blast_Score=90, Evalue=4e-19,
Organism=Homo sapiens, GI224809331, Length=101, Percent_Identity=49.5049504950495, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI224809329, Length=101, Percent_Identity=49.5049504950495, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI224809327, Length=101, Percent_Identity=49.5049504950495, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI4758384, Length=101, Percent_Identity=49.5049504950495, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI192448443, Length=96, Percent_Identity=47.9166666666667, Blast_Score=86, Evalue=6e-18,
Organism=Homo sapiens, GI8923659, Length=98, Percent_Identity=46.9387755102041, Blast_Score=85, Evalue=1e-17,
Organism=Homo sapiens, GI33469985, Length=110, Percent_Identity=40.9090909090909, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI206725547, Length=97, Percent_Identity=41.2371134020619, Blast_Score=72, Evalue=8e-14,
Organism=Homo sapiens, GI31317231, Length=98, Percent_Identity=41.8367346938776, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082390, Length=115, Percent_Identity=46.0869565217391, Blast_Score=91, Evalue=1e-20,
Organism=Escherichia coli, GI1789745, Length=115, Percent_Identity=44.3478260869565, Blast_Score=81, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71993519, Length=110, Percent_Identity=51.8181818181818, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17540882, Length=96, Percent_Identity=47.9166666666667, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561782, Length=95, Percent_Identity=49.4736842105263, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17561778, Length=99, Percent_Identity=41.4141414141414, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71993555, Length=86, Percent_Identity=44.1860465116279, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320727, Length=108, Percent_Identity=52.7777777777778, Blast_Score=107, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324194, Length=115, Percent_Identity=48.695652173913, Blast_Score=102, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323566, Length=109, Percent_Identity=48.6238532110092, Blast_Score=89, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323482, Length=109, Percent_Identity=44.954128440367, Blast_Score=83, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363946, Length=96, Percent_Identity=57.2916666666667, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17352457, Length=96, Percent_Identity=57.2916666666667, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24655568, Length=110, Percent_Identity=53.6363636363636, Blast_Score=109, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24647110, Length=113, Percent_Identity=51.3274336283186, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583150, Length=91, Percent_Identity=47.2527472527472, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356629, Length=97, Percent_Identity=53.6082474226804, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12320; Mature: 12189

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIETTASGLQYEDVVVGDGAQATAGQYVTVHYTGWLYENGQAGKKFDSSKDRNDPFAFH
CEECCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEE
LGGGMVIKGWDEGVQGMKVGGTRKLIIPAALGYGARGAGGVIPPNATLLFEVDLLEV
ECCCEEEECCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
TIETTASGLQYEDVVVGDGAQATAGQYVTVHYTGWLYENGQAGKKFDSSKDRNDPFAFH
EECCCCCCCEEEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEE
LGGGMVIKGWDEGVQGMKVGGTRKLIIPAALGYGARGAGGVIPPNATLLFEVDLLEV
ECCCEEEECCCCCCCCEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]