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The map label for this gene is pdxH1 [H]

Identifier: 187927813

GI number: 187927813

Start: 751848

End: 752486

Strand: Reverse

Name: pdxH1 [H]

Synonym: Rpic_0717

Alternate gene names: 187927813

Gene position: 752486-751848 (Counterclockwise)

Preceding gene: 187927817

Following gene: 187927812

Centisome position: 19.09

GC content: 68.54

Gene sequence:

>639_bases
ATGACCTCCATTGCCGATATCCGCACCGATTACGCCCGCGCTTCGCTCGACATCGCCGACGTCGACGCCAGCCCCCTGCG
CCAGTTCCGCCGCTGGTTCGACGAGGCCCTGAAAGCCGAGGTGGCTGAAGTCAACGCCATGACGCTCGCCACGGTGGACC
CGCATGGCCAGCCCTCGGCCCGCATCGTCCTGCTCAAGAACCTGGACGAACGCGGCTTCACGTTCTTCACGAACTACGCC
AGCCACAAGGGCGAGGAACTGGCCGCCAACCCCCGCGCTGCGCTGCTGTTCCACTGGATCGGGCTGGAGCGGCAGGTGCG
CGTACAAGGCATCGTCGAAAAAGTGAGCGAGGCAGAGAGCGATGCCTATTACCACTCGCGGCCGCTGGGCTCGCGCCTGG
GCGCCTGGGCGTCGGAGCAGAGCAGCGAAGTGCCCGACCGCGCCACGCTGGAAGCGCGCGAAGCCGAATACCGCCAGCGC
TTTGGCGATGCCCCGCCGCGCCCGCCCCACTGGGGCGGCTACCGGCTGCTGCCCGAGCGGCTGGAATTCTGGCAAGGCCG
CCCGTCGCGGCTGCACGATCGGCTGGAGTACCGCAAGCATGCCGACGGCAGCTGGACAATCGTCCGCCTCGCCCCGTAG

Upstream 100 bases:

>100_bases
GCCCCACGCGCAAAGCGTGCCAGCCCTTGCGCGCGAGCAAAGAACGGCAGGCCGTGTTTGTCTATACTCGGCCCGTCCGC
ATGCCGCATTCGCCACGCTC

Downstream 100 bases:

>100_bases
CCTGACGACAGATGCGCAATACGTTATTGCGCATCGCGTCATGCCGGCACGGCGCTTGCTGCCGAAGGATCGGGCCGGCA
CGTCCCCGTAAGATCCGCAC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase 1; PNPOx 1; Pyridoxal 5'-phosphate synthase 1 [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTSIADIRTDYARASLDIADVDASPLRQFRRWFDEALKAEVAEVNAMTLATVDPHGQPSARIVLLKNLDERGFTFFTNYA
SHKGEELAANPRAALLFHWIGLERQVRVQGIVEKVSEAESDAYYHSRPLGSRLGAWASEQSSEVPDRATLEAREAEYRQR
FGDAPPRPPHWGGYRLLPERLEFWQGRPSRLHDRLEYRKHADGSWTIVRLAP

Sequences:

>Translated_212_residues
MTSIADIRTDYARASLDIADVDASPLRQFRRWFDEALKAEVAEVNAMTLATVDPHGQPSARIVLLKNLDERGFTFFTNYA
SHKGEELAANPRAALLFHWIGLERQVRVQGIVEKVSEAESDAYYHSRPLGSRLGAWASEQSSEVPDRATLEAREAEYRQR
FGDAPPRPPHWGGYRLLPERLEFWQGRPSRLHDRLEYRKHADGSWTIVRLAP
>Mature_211_residues
TSIADIRTDYARASLDIADVDASPLRQFRRWFDEALKAEVAEVNAMTLATVDPHGQPSARIVLLKNLDERGFTFFTNYAS
HKGEELAANPRAALLFHWIGLERQVRVQGIVEKVSEAESDAYYHSRPLGSRLGAWASEQSSEVPDRATLEAREAEYRQRF
GDAPPRPPHWGGYRLLPERLEFWQGRPSRLHDRLEYRKHADGSWTIVRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=177, Percent_Identity=49.7175141242938, Blast_Score=183, Evalue=1e-46,
Organism=Escherichia coli, GI1787926, Length=213, Percent_Identity=46.9483568075117, Blast_Score=198, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17553712, Length=220, Percent_Identity=41.8181818181818, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=44.0191387559809, Blast_Score=176, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45551845, Length=205, Percent_Identity=42.4390243902439, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644901, Length=205, Percent_Identity=42.4390243902439, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24644903, Length=163, Percent_Identity=30.0613496932515, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24209; Mature: 24078

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIADIRTDYARASLDIADVDASPLRQFRRWFDEALKAEVAEVNAMTLATVDPHGQPSA
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCE
RIVLLKNLDERGFTFFTNYASHKGEELAANPRAALLFHWIGLERQVRVQGIVEKVSEAES
EEEEEECCCCCCCEEEECHHHCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DAYYHSRPLGSRLGAWASEQSSEVPDRATLEAREAEYRQRFGDAPPRPPHWGGYRLLPER
CHHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHH
LEFWQGRPSRLHDRLEYRKHADGSWTIVRLAP
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
TSIADIRTDYARASLDIADVDASPLRQFRRWFDEALKAEVAEVNAMTLATVDPHGQPSA
CCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCE
RIVLLKNLDERGFTFFTNYASHKGEELAANPRAALLFHWIGLERQVRVQGIVEKVSEAES
EEEEEECCCCCCCEEEECHHHCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DAYYHSRPLGSRLGAWASEQSSEVPDRATLEAREAEYRQRFGDAPPRPPHWGGYRLLPER
CHHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECHHH
LEFWQGRPSRLHDRLEYRKHADGSWTIVRLAP
HHHHCCCHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]