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The map label for this gene is kynB

Identifier: 187927806

GI number: 187927806

Start: 746393

End: 747022

Strand: Reverse

Name: kynB

Synonym: Rpic_0710

Alternate gene names: 187927806

Gene position: 747022-746393 (Counterclockwise)

Preceding gene: 187927809

Following gene: 187927805

Centisome position: 18.95

GC content: 67.62

Gene sequence:

>630_bases
TTGGAACGCACTTTGTGGGACATCACCCCCGCCCTTTCGCCCACCACGCCCACGTGGCCCGGCGACACGCCGTTTTCGCA
GGAAATTGCGTGGAAGCTCGAAGGTGACTGCCCGGTCAATGTCGGACGCATTACGCTCTCGCCGCACACGGGTGCCCATG
CCGATGCGCCGCTCCACTACCGCGCGGACGGCGCTGCCATCGGCCAGGTGCCGCTGGACGCCTACCTGGGCCTGTGCCGC
GTTATCCACTGCGTAGGTGTAGCGCGCGTCGAGCCGGAACACGTGCGCGACGCATTGACCAACGCACCGCCGCGCGTGCT
GCTGCGCACGTACGCGCATATGCCGCAGACCGCGTGGGACAACGACTTTGCCGCCGTTGCGCCCGAGACCATCGCGCTGC
TGGCCACGCACGGTGTCAAGCTCATCGGCGTCGACACCGCCTCGCTCGATCCGCAGACCTCCAAGACCATGGACGCGCAC
CACGCCGTTGGCAAACACGGCCTCGCGATCCTCGAAGGGCTGCTGCTCGACGACGTGCCCGCCGGTGACTACGAACTGAT
CGCCCTGCCACTCAAGTTCGCCACCCTCGATGCCAGCCCGGTTCGCGCCGTGCTGCGCAGCCTGCCCTGA

Upstream 100 bases:

>100_bases
AATCCATCGAACTCACACGCACGATTATGCAAACCCATTGCGCGCGGATTTCCCTATCATTTCGACACGGATTCACCGAT
TTTCTTGCCCTGGAGCCGCC

Downstream 100 bases:

>100_bases
TCGATACAACGACAGAACACAAACCGCTTTTTCGCTCCCGTAATCACATGACCATCACCCGCAACTCCTGCCTCGAACGC
GACGCGGCCGATCCGATCGC

Product: arylformamidase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MERTLWDITPALSPTTPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHYRADGAAIGQVPLDAYLGLCR
VIHCVGVARVEPEHVRDALTNAPPRVLLRTYAHMPQTAWDNDFAAVAPETIALLATHGVKLIGVDTASLDPQTSKTMDAH
HAVGKHGLAILEGLLLDDVPAGDYELIALPLKFATLDASPVRAVLRSLP

Sequences:

>Translated_209_residues
MERTLWDITPALSPTTPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHYRADGAAIGQVPLDAYLGLCR
VIHCVGVARVEPEHVRDALTNAPPRVLLRTYAHMPQTAWDNDFAAVAPETIALLATHGVKLIGVDTASLDPQTSKTMDAH
HAVGKHGLAILEGLLLDDVPAGDYELIALPLKFATLDASPVRAVLRSLP
>Mature_209_residues
MERTLWDITPALSPTTPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHYRADGAAIGQVPLDAYLGLCR
VIHCVGVARVEPEHVRDALTNAPPRVLLRTYAHMPQTAWDNDFAAVAPETIALLATHGVKLIGVDTASLDPQTSKTMDAH
HAVGKHGLAILEGLLLDDVPAGDYELIALPLKFATLDASPVRAVLRSLP

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_RALPJ (B2U7J9)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898293.1
- ProteinModelPortal:   B2U7J9
- GeneID:   6289492
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0710
- HOGENOM:   HBG686791
- OMA:   CPVNVGR
- ProtClustDB:   CLSK2302456
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 22373; Mature: 22373

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTLWDITPALSPTTPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEECEEEECCCCCCCCCCCEEE
RADGAAIGQVPLDAYLGLCRVIHCVGVARVEPEHVRDALTNAPPRVLLRTYAHMPQTAWD
ECCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
NDFAAVAPETIALLATHGVKLIGVDTASLDPQTSKTMDAHHAVGKHGLAILEGLLLDDVP
CCCHHHCHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
AGDYELIALPLKFATLDASPVRAVLRSLP
CCCEEEEEEEEEEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MERTLWDITPALSPTTPTWPGDTPFSQEIAWKLEGDCPVNVGRITLSPHTGAHADAPLHY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEECEEEECCCCCCCCCCCEEE
RADGAAIGQVPLDAYLGLCRVIHCVGVARVEPEHVRDALTNAPPRVLLRTYAHMPQTAWD
ECCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
NDFAAVAPETIALLATHGVKLIGVDTASLDPQTSKTMDAHHAVGKHGLAILEGLLLDDVP
CCCHHHCHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
AGDYELIALPLKFATLDASPVRAVLRSLP
CCCEEEEEEEEEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA