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The map label for this gene is tolR [H]

Identifier: 187927778

GI number: 187927778

Start: 720524

End: 720958

Strand: Direct

Name: tolR [H]

Synonym: Rpic_0682

Alternate gene names: 187927778

Gene position: 720524-720958 (Clockwise)

Preceding gene: 187927777

Following gene: 187927779

Centisome position: 18.28

GC content: 62.07

Gene sequence:

>435_bases
ATGGCTACCATCCAGCGAACGCGCCGCGCCCGACGGGCCAAGGCTGACATCAACGTTGTTCCGTACATCGACGTGATGCT
GGTGCTGCTGGTCATCTTCATGGTGGCGGCACCCGTCGTGAACCCGGGCGTGGTCAATCTGCCCTCGGTGGCCAACGCCA
CGCCGCAGCAGACCCAGCCGCCCATCGTCGTGACGATCAAGGGCGACGGCACGATCCTTGCTCGCATCAAGACCGGTTCG
GGAGCAACCGAGCAGAAGCTCGCCAACAACAACGAGCTGCGCGCATTTGTGAAGCAGCGCACTGACGAAAATCCTGATCA
GCCCGTCGTGATTGCCGCCGACAAGTCGGTCCAGTATGACCGCGTGCTGACCGTGATGAGCGTGCTCAAGGGCGATGGCG
TGAAGCGCGTCGGCCTGATGGTGAAATCGTCATGA

Upstream 100 bases:

>100_bases
CTACGCCACCGAAATGGACCGCCTGGCCAACCGGTTCGAGAGCTTCATGGAAGAGTTCTCGAACATCCTCCAGCGCCAGA
CGCGCTAAGGAGTCGCGCTC

Downstream 100 bases:

>100_bases
GCACGCTGAAGAATCCGGGCGAGGCAACCTGAACGTCATGGCTACGACGTCGTTGCACCGTTACGAGCCTGTTCGCGAGC
GCGGCACGCTGCGCGCATTC

Product: protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MATIQRTRRARRAKADINVVPYIDVMLVLLVIFMVAAPVVNPGVVNLPSVANATPQQTQPPIVVTIKGDGTILARIKTGS
GATEQKLANNNELRAFVKQRTDENPDQPVVIAADKSVQYDRVLTVMSVLKGDGVKRVGLMVKSS

Sequences:

>Translated_144_residues
MATIQRTRRARRAKADINVVPYIDVMLVLLVIFMVAAPVVNPGVVNLPSVANATPQQTQPPIVVTIKGDGTILARIKTGS
GATEQKLANNNELRAFVKQRTDENPDQPVVIAADKSVQYDRVLTVMSVLKGDGVKRVGLMVKSS
>Mature_143_residues
ATIQRTRRARRAKADINVVPYIDVMLVLLVIFMVAAPVVNPGVVNLPSVANATPQQTQPPIVVTIKGDGTILARIKTGSG
ATEQKLANNNELRAFVKQRTDENPDQPVVIAADKSVQYDRVLTVMSVLKGDGVKRVGLMVKSS

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1789380, Length=126, Percent_Identity=38.0952380952381, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15545; Mature: 15414

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIQRTRRARRAKADINVVPYIDVMLVLLVIFMVAAPVVNPGVVNLPSVANATPQQTQP
CCCHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC
PIVVTIKGDGTILARIKTGSGATEQKLANNNELRAFVKQRTDENPDQPVVIAADKSVQYD
CEEEEEECCCEEEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHH
RVLTVMSVLKGDGVKRVGLMVKSS
HHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure 
ATIQRTRRARRAKADINVVPYIDVMLVLLVIFMVAAPVVNPGVVNLPSVANATPQQTQP
CCHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC
PIVVTIKGDGTILARIKTGSGATEQKLANNNELRAFVKQRTDENPDQPVVIAADKSVQYD
CEEEEEECCCEEEEEEECCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHH
RVLTVMSVLKGDGVKRVGLMVKSS
HHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]