Click here to switch to the map view.

The map label for this gene is pilH [H]

Identifier: 187927709

GI number: 187927709

Start: 648549

End: 648917

Strand: Direct

Name: pilH [H]

Synonym: Rpic_0613

Alternate gene names: 187927709

Gene position: 648549-648917 (Clockwise)

Preceding gene: 187927708

Following gene: 187927710

Centisome position: 16.45

GC content: 60.98

Gene sequence:

>369_bases
ATGGCAATCAAGAAAGTGTTGGTGGTCGATGATTCTCCGACCGAAGCGCTGCACCTGTCGGAGATCCTCGGCAAGAACGG
TTTCAAAGTGACGGTCGCTGCCGATAGCGAGCAGGCCATGACCAAGCTCGAAGCCGAAACCTTCGACCTGATCCTGATGG
ACGTGGTGATGCCGGGCCAGAACGGCTACCAGGCGACCCGCGCCATCAAGAAGGACGAGCGCTTCCAGGGCATCCCCGTG
ATCATGTGCACGACCAAGGGCCTGGAGACCGACCGCGTGTGGGGCATGCGCCAGGGCGCATCGGACTACATCGTCAAGCC
GGTCAAGGCCGAAGAGCTGCTCGAGAAGATCGCCAAGCTGGCGCAGTGA

Upstream 100 bases:

>100_bases
GTTCTCGAAGGAAGCGCTGCTGGAGGCGGTCCAGACGCATTTGCCGGTGGCGCGAGCTGCCGCGCAGTGACGGCATCTCT
TTTAACGAAGGACTGTTTGT

Downstream 100 bases:

>100_bases
TCCTGCGGCAGTTCGTTTAGAAGCGCGACGTCGAGACCGCGCGCAGCAAAGACCCAGCACCGGACATGAGCCAGACGTGA
ACGAACAGCGCACCAACCTG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MAIKKVLVVDDSPTEALHLSEILGKNGFKVTVAADSEQAMTKLEAETFDLILMDVVMPGQNGYQATRAIKKDERFQGIPV
IMCTTKGLETDRVWGMRQGASDYIVKPVKAEELLEKIAKLAQ

Sequences:

>Translated_122_residues
MAIKKVLVVDDSPTEALHLSEILGKNGFKVTVAADSEQAMTKLEAETFDLILMDVVMPGQNGYQATRAIKKDERFQGIPV
IMCTTKGLETDRVWGMRQGASDYIVKPVKAEELLEKIAKLAQ
>Mature_121_residues
AIKKVLVVDDSPTEALHLSEILGKNGFKVTVAADSEQAMTKLEAETFDLILMDVVMPGQNGYQATRAIKKDERFQGIPVI
MCTTKGLETDRVWGMRQGASDYIVKPVKAEELLEKIAKLAQ

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=37.719298245614, Blast_Score=85, Evalue=1e-18,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=38.9380530973451, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1788394, Length=113, Percent_Identity=32.7433628318584, Blast_Score=74, Evalue=4e-15,
Organism=Escherichia coli, GI2367329, Length=115, Percent_Identity=40, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1787229, Length=117, Percent_Identity=29.9145299145299, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13467; Mature: 13336

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKKVLVVDDSPTEALHLSEILGKNGFKVTVAADSEQAMTKLEAETFDLILMDVVMPGQ
CCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHEEEEEEECCCC
NGYQATRAIKKDERFQGIPVIMCTTKGLETDRVWGMRQGASDYIVKPVKAEELLEKIAKL
CCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
AQ
CC
>Mature Secondary Structure 
AIKKVLVVDDSPTEALHLSEILGKNGFKVTVAADSEQAMTKLEAETFDLILMDVVMPGQ
CCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHEEEEEEECCCC
NGYQATRAIKKDERFQGIPVIMCTTKGLETDRVWGMRQGASDYIVKPVKAEELLEKIAKL
CCHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHH
AQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]