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The map label for this gene is tcpI [H]

Identifier: 187927609

GI number: 187927609

Start: 545486

End: 546898

Strand: Direct

Name: tcpI [H]

Synonym: Rpic_0509

Alternate gene names: 187927609

Gene position: 545486-546898 (Clockwise)

Preceding gene: 187927608

Following gene: 187927614

Centisome position: 13.84

GC content: 63.62

Gene sequence:

>1413_bases
GTGAAGCCATTCGCCTGGGGCCGCGGCCCGAAAGCCTCTCCCGACCTTGTTGCCCGTATTGCCGAAGAGGCCGGCCGCGT
CGGCATGGGCATCTGCGAGGTCTCCGGCAACGTGGAAGACGTGGCCGTGCGCCTGCGCCGGCAGGCCGACGTGTTCGATC
AGTTGCGCAACGCGGCCGATGTCACCATGCGCGGCAATCACGATATCGCCGTAGCGGCGCAGCACGCGCGCAAAGTCGCA
TCGCATGCCAGCGAAGAGGTGAGCGGCTCGCGCGAAACGGTCGATGCATCGCTGCGCGACATTCGCGAGTTGGCCGTTGG
TGTGGCGAGCATGGAACAGCAGATTGCTGCACTGCGTGAAGCGCTGATCCAGGTGGCGCAGGCGTCCGAGCAGATTTCGC
AGATTGCCAGGCAGACCAATCTGCTGGCAATCAACGCCGCCATTGAAGCGGCGCGCGCGGGGGAATCGGGCCGCAGCTTT
GCAGTGGTTGCGGGCGCAGTGAAGCAGCTCGCTGGACAGACCGCCGAAGCAACCCAGCGTATCGAAACCACCTTGGCGGA
TTTGTCTGGCCAGACCGACAAGCTGATCGGCGACAGCAGTGCAAACGTTGCGCGCGCCCAGCGTGTGGATGCCGGCACGC
AGGCCATTGGCGCGGTGATTGGCGTGGCGGGCGAGGCCATTGCGCGCTTCGATGTCGAGGCGACCAGCATTGCGGAATCC
ACTGCGGCCATCGAAGACGAATGCGCGTCGCTCGCGCGTGAGGTGGAGGCGATGGCTGAGGGTGTGAAGCAATCGAGCCA
CAACATCGACAACGCGCAACGGCAGCTTTCGGGGTTGCTGGGGGCGTCGGAAACGCTGATCCGGTTGACGGCCTCAACGG
GTGTGCAGAGTGCCGATACGCCGTTCATCGAAGCGGTGCAGACCGCCGCCGGCAAGATCAGCGCATTGTTTGAATCGGCG
CTGGCGCGCGGCGATATCAATGAGGGCGATTTGTTCGACCGCACCTATGCGCCTGTGCCGAATACCGACCCGCCGCAGCA
TATGACGCGGTTCACGACGTTCACGGACCGTGTGTTGCCTGCGGTACAGGAGCCGTTGCTCCAGTTGGATCCACGCGTGG
TGTTTTGTGCGGCGGTCGACACCAACGGCTACCTTCCGACGCACAACCTGAAGTTCTCGCAGCCGCAGGGGAGTGATCCG
GTCTTGAATGCGGCCAACAGCCGCAACCGCCGGCTGTTCACCGATCGCACGGGGCTGGGGGCCGCGCGCAATACTGAGGC
ATTTTTGTTGCAGACGTATCGTCGCGATATGGGCAACGGGACGTTTGCGATGATGAAGGATGTGTCGGCGCCGATTTACG
TCAAGGGCCGTCACTGGGGTGGTTTCCGGATGGGCTACAAGGTGGCCGGTTAA

Upstream 100 bases:

>100_bases
CGCTCAAGCGCGCTTCGCACGTGCCGATACCCCCCTTAGAGGGCCGCTTCGCCATCAGCGCGAGGGCGCACACAACAACG
ACAATTGGAGACAACCGCAC

Downstream 100 bases:

>100_bases
GGTCCGTAACGCCGGGGTTGGGGTTCTGAACTTCGCTGATGGGGTTCGGAACGGAAATGCTGAGGTTCGGAACCGCATTC
GTGGGGTTCAGAACTGCGTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MKPFAWGRGPKASPDLVARIAEEAGRVGMGICEVSGNVEDVAVRLRRQADVFDQLRNAADVTMRGNHDIAVAAQHARKVA
SHASEEVSGSRETVDASLRDIRELAVGVASMEQQIAALREALIQVAQASEQISQIARQTNLLAINAAIEAARAGESGRSF
AVVAGAVKQLAGQTAEATQRIETTLADLSGQTDKLIGDSSANVARAQRVDAGTQAIGAVIGVAGEAIARFDVEATSIAES
TAAIEDECASLAREVEAMAEGVKQSSHNIDNAQRQLSGLLGASETLIRLTASTGVQSADTPFIEAVQTAAGKISALFESA
LARGDINEGDLFDRTYAPVPNTDPPQHMTRFTTFTDRVLPAVQEPLLQLDPRVVFCAAVDTNGYLPTHNLKFSQPQGSDP
VLNAANSRNRRLFTDRTGLGAARNTEAFLLQTYRRDMGNGTFAMMKDVSAPIYVKGRHWGGFRMGYKVAG

Sequences:

>Translated_470_residues
MKPFAWGRGPKASPDLVARIAEEAGRVGMGICEVSGNVEDVAVRLRRQADVFDQLRNAADVTMRGNHDIAVAAQHARKVA
SHASEEVSGSRETVDASLRDIRELAVGVASMEQQIAALREALIQVAQASEQISQIARQTNLLAINAAIEAARAGESGRSF
AVVAGAVKQLAGQTAEATQRIETTLADLSGQTDKLIGDSSANVARAQRVDAGTQAIGAVIGVAGEAIARFDVEATSIAES
TAAIEDECASLAREVEAMAEGVKQSSHNIDNAQRQLSGLLGASETLIRLTASTGVQSADTPFIEAVQTAAGKISALFESA
LARGDINEGDLFDRTYAPVPNTDPPQHMTRFTTFTDRVLPAVQEPLLQLDPRVVFCAAVDTNGYLPTHNLKFSQPQGSDP
VLNAANSRNRRLFTDRTGLGAARNTEAFLLQTYRRDMGNGTFAMMKDVSAPIYVKGRHWGGFRMGYKVAG
>Mature_470_residues
MKPFAWGRGPKASPDLVARIAEEAGRVGMGICEVSGNVEDVAVRLRRQADVFDQLRNAADVTMRGNHDIAVAAQHARKVA
SHASEEVSGSRETVDASLRDIRELAVGVASMEQQIAALREALIQVAQASEQISQIARQTNLLAINAAIEAARAGESGRSF
AVVAGAVKQLAGQTAEATQRIETTLADLSGQTDKLIGDSSANVARAQRVDAGTQAIGAVIGVAGEAIARFDVEATSIAES
TAAIEDECASLAREVEAMAEGVKQSSHNIDNAQRQLSGLLGASETLIRLTASTGVQSADTPFIEAVQTAAGKISALFESA
LARGDINEGDLFDRTYAPVPNTDPPQHMTRFTTFTDRVLPAVQEPLLQLDPRVVFCAAVDTNGYLPTHNLKFSQPQGSDP
VLNAANSRNRRLFTDRTGLGAARNTEAFLLQTYRRDMGNGTFAMMKDVSAPIYVKGRHWGGFRMGYKVAG

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=262, Percent_Identity=30.5343511450382, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788195, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI2367378, Length=170, Percent_Identity=35.8823529411765, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788194, Length=119, Percent_Identity=37.8151260504202, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789453, Length=130, Percent_Identity=39.2307692307692, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 49955; Mature: 49955

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFAWGRGPKASPDLVARIAEEAGRVGMGICEVSGNVEDVAVRLRRQADVFDQLRNAAD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
VTMRGNHDIAVAAQHARKVASHASEEVSGSRETVDASLRDIRELAVGVASMEQQIAALRE
EEEECCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIQVAQASEQISQIARQTNLLAINAAIEAARAGESGRSFAVVAGAVKQLAGQTAEATQR
HHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHH
IETTLADLSGQTDKLIGDSSANVARAQRVDAGTQAIGAVIGVAGEAIARFDVEATSIAES
HHHHHHHHCCCCHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TAAIEDECASLAREVEAMAEGVKQSSHNIDNAQRQLSGLLGASETLIRLTASTGVQSADT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCC
PFIEAVQTAAGKISALFESALARGDINEGDLFDRTYAPVPNTDPPQHMTRFTTFTDRVLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AVQEPLLQLDPRVVFCAAVDTNGYLPTHNLKFSQPQGSDPVLNAANSRNRRLFTDRTGLG
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCEECCCCCCCEEEECCCCCC
AARNTEAFLLQTYRRDMGNGTFAMMKDVSAPIYVKGRHWGGFRMGYKVAG
CCCCCHHHHHHHHHHHCCCCCEEHHHHCCCCEEEECCCCCCEECCCEECC
>Mature Secondary Structure
MKPFAWGRGPKASPDLVARIAEEAGRVGMGICEVSGNVEDVAVRLRRQADVFDQLRNAAD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
VTMRGNHDIAVAAQHARKVASHASEEVSGSRETVDASLRDIRELAVGVASMEQQIAALRE
EEEECCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIQVAQASEQISQIARQTNLLAINAAIEAARAGESGRSFAVVAGAVKQLAGQTAEATQR
HHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHH
IETTLADLSGQTDKLIGDSSANVARAQRVDAGTQAIGAVIGVAGEAIARFDVEATSIAES
HHHHHHHHCCCCHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TAAIEDECASLAREVEAMAEGVKQSSHNIDNAQRQLSGLLGASETLIRLTASTGVQSADT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCC
PFIEAVQTAAGKISALFESALARGDINEGDLFDRTYAPVPNTDPPQHMTRFTTFTDRVLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AVQEPLLQLDPRVVFCAAVDTNGYLPTHNLKFSQPQGSDPVLNAANSRNRRLFTDRTGLG
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCEECCCCCCCEEEECCCCCC
AARNTEAFLLQTYRRDMGNGTFAMMKDVSAPIYVKGRHWGGFRMGYKVAG
CCCCCHHHHHHHHHHHCCCCCEEHHHHCCCCEEEECCCCCCEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]