| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
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The map label for this gene is purK [H]
Identifier: 187927596
GI number: 187927596
Start: 528257
End: 529492
Strand: Direct
Name: purK [H]
Synonym: Rpic_0496
Alternate gene names: 187927596
Gene position: 528257-529492 (Clockwise)
Preceding gene: 187927595
Following gene: 187927597
Centisome position: 13.4
GC content: 67.15
Gene sequence:
>1236_bases ATGGCCGACGACCTGAACCCGCGCCTGGCGCAAGCCCACACCGCGGAATCCCGCGCGCTGAACGTTCCCAACGCGATCCT GCCCGATGCGTGGCTTGGCATGCTCGGCGGCGGCCAGCTCGGCCGCATGTTCACGCACGCCGCACAGGCGATGGGCTACA AGGTCTGCGTGCTCGATCCGGACCCGAACAGCCCCGCCGGCACCATCGCCGAGCGCCATCTGTGCGCTGGCTATACCGAT GAAGCCGCTTTGGCCGAGATGGCTGCGCTGTGCCCCGCGGTGACCACCGAATTCGAGAACGTGCCGGCGCAAGCGCTGGA CAAGCTTGAGCAACTCGGCGCGTTCGTGGCGCCGCGTGCCAATTGTGTGTCGATCGCGCAGAACCGCATCGCCGAGAAAA AATTCTTCGCGCTGTGCGCCGCACGCACGGGCATCCACCCCGCACCGAGCTGGGTGATCGAGCATGAAGCCGATATCGAG CAACTCCCCGCCGACCTGCTGCCCGGCATCCTGAAAATTGCCCGCATGGGGTACGACGGCAAGGGCCAGGCGCGTGTCTC GACGATTGAAGAGTTGCGCGCCGCCTGGGGCGCCATGCAGCACGTGCCGTGCGTGCTGGAGAAGATGCTGCCGCTGGCCT ACGAGGTGTCCGTGCTGGCCGCGCGCGGTGCCGATGGCAGCACGGCCACCTGGCCGCTGGCCGAGAACGTGCACCGTGAC GGCATCCTGTTCTCAACGATCATGCCGTCGCGCAGCGTGTCAGACGACATTGCCACGCGCACACGCGCCGCTGCCGCGAT GATCGCCGAAGAGATGGGCTACGTCGGCGTGCTGTGCATCGAGTTCTTCGTGCTGCAGGACGGCTCGCTGGTGGCCAATG AAATGGCGCCGCGCCCGCACAACTCCGGTCACATCACCATGGATGTGTGCGAGACGAGCCAGTTCGAGCAACAGGTGCGC GCCATGGCCCGCCTGCCGCTGGGCAGCACGCGGCAGCACTCGCCGGGGCGCATGCTGAATGTGCTGGGCGACGTGTGGTT TGAGTACGGGCTGGAACGTACGCCCGCGTGGCACGAAGTGATGGGCCACAGCGGTGCGAAGGTCCACCTGTATGGCAAGG CCGATGCGCGGCCGGGCCGCAAGATGGGCCACGTGAACTGCGTCGGCACCTCGCCAGAAGTGGTGGACGAGGCGTTCCGC CACGCCGCGCACGTGCTCGGCCTGCAGTCCGACTAA
Upstream 100 bases:
>100_bases CTTGCCGACAAGCTCGAAGCTTTCCGCGCCCAGCAGACCGAAGTCGCACGCGGCATGACGCTCCCTGTGCACGGCGCCTA AGTAACCTACGACCCGATTC
Downstream 100 bases:
>100_bases AGACGAGCCGCCCATGCCGCATCGGACCACATCGCCCTACACCATGCCTTCCGCTGAGCGCCTCGATGAGGCCGCGCGCA GGCTGGAGGCAGGCGAGCTG
Product: phosphoribosylaminoimidazole carboxylase ATPase
Products: NA
Alternate protein names: N5-CAIR synthase; 5-(carboxyamino)imidazole ribonucleotide synthetase [H]
Number of amino acids: Translated: 411; Mature: 410
Protein sequence:
>411_residues MADDLNPRLAQAHTAESRALNVPNAILPDAWLGMLGGGQLGRMFTHAAQAMGYKVCVLDPDPNSPAGTIAERHLCAGYTD EAALAEMAALCPAVTTEFENVPAQALDKLEQLGAFVAPRANCVSIAQNRIAEKKFFALCAARTGIHPAPSWVIEHEADIE QLPADLLPGILKIARMGYDGKGQARVSTIEELRAAWGAMQHVPCVLEKMLPLAYEVSVLAARGADGSTATWPLAENVHRD GILFSTIMPSRSVSDDIATRTRAAAAMIAEEMGYVGVLCIEFFVLQDGSLVANEMAPRPHNSGHITMDVCETSQFEQQVR AMARLPLGSTRQHSPGRMLNVLGDVWFEYGLERTPAWHEVMGHSGAKVHLYGKADARPGRKMGHVNCVGTSPEVVDEAFR HAAHVLGLQSD
Sequences:
>Translated_411_residues MADDLNPRLAQAHTAESRALNVPNAILPDAWLGMLGGGQLGRMFTHAAQAMGYKVCVLDPDPNSPAGTIAERHLCAGYTD EAALAEMAALCPAVTTEFENVPAQALDKLEQLGAFVAPRANCVSIAQNRIAEKKFFALCAARTGIHPAPSWVIEHEADIE QLPADLLPGILKIARMGYDGKGQARVSTIEELRAAWGAMQHVPCVLEKMLPLAYEVSVLAARGADGSTATWPLAENVHRD GILFSTIMPSRSVSDDIATRTRAAAAMIAEEMGYVGVLCIEFFVLQDGSLVANEMAPRPHNSGHITMDVCETSQFEQQVR AMARLPLGSTRQHSPGRMLNVLGDVWFEYGLERTPAWHEVMGHSGAKVHLYGKADARPGRKMGHVNCVGTSPEVVDEAFR HAAHVLGLQSD >Mature_410_residues ADDLNPRLAQAHTAESRALNVPNAILPDAWLGMLGGGQLGRMFTHAAQAMGYKVCVLDPDPNSPAGTIAERHLCAGYTDE AALAEMAALCPAVTTEFENVPAQALDKLEQLGAFVAPRANCVSIAQNRIAEKKFFALCAARTGIHPAPSWVIEHEADIEQ LPADLLPGILKIARMGYDGKGQARVSTIEELRAAWGAMQHVPCVLEKMLPLAYEVSVLAARGADGSTATWPLAENVHRDG ILFSTIMPSRSVSDDIATRTRAAAAMIAEEMGYVGVLCIEFFVLQDGSLVANEMAPRPHNSGHITMDVCETSQFEQQVRA MARLPLGSTRQHSPGRMLNVLGDVWFEYGLERTPAWHEVMGHSGAKVHLYGKADARPGRKMGHVNCVGTSPEVVDEAFRH AAHVLGLQSD
Specific function: Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) [H]
COG id: COG0026
COG function: function code F; Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-grasp domain [H]
Homologues:
Organism=Escherichia coli, GI1786733, Length=358, Percent_Identity=33.7988826815642, Blast_Score=145, Evalue=5e-36, Organism=Escherichia coli, GI1788155, Length=389, Percent_Identity=25.706940874036, Blast_Score=103, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6324702, Length=374, Percent_Identity=31.283422459893, Blast_Score=186, Evalue=8e-48,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005875 - InterPro: IPR011761 - InterPro: IPR003135 - InterPro: IPR013816 - InterPro: IPR013817 - InterPro: IPR016185 - InterPro: IPR011054 [H]
Pfam domain/function: PF02222 ATP-grasp [H]
EC number: =6.3.4.18 [H]
Molecular weight: Translated: 44283; Mature: 44152
Theoretical pI: Translated: 5.95; Mature: 5.95
Prosite motif: PS50975 ATP_GRASP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 6.3 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 6.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADDLNPRLAQAHTAESRALNVPNAILPDAWLGMLGGGQLGRMFTHAAQAMGYKVCVLDP CCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECC DPNSPAGTIAERHLCAGYTDEAALAEMAALCPAVTTEFENVPAQALDKLEQLGAFVAPRA CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCH NCVSIAQNRIAEKKFFALCAARTGIHPAPSWVIEHEADIEQLPADLLPGILKIARMGYDG HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHCCHHHHHHHHHHHHCCCCC KGQARVSTIEELRAAWGAMQHVPCVLEKMLPLAYEVSVLAARGADGSTATWPLAENVHRD CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHCCCCC GILFSTIMPSRSVSDDIATRTRAAAAMIAEEMGYVGVLCIEFFVLQDGSLVANEMAPRPH CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCC NSGHITMDVCETSQFEQQVRAMARLPLGSTRQHSPGRMLNVLGDVWFEYGLERTPAWHEV CCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH MGHSGAKVHLYGKADARPGRKMGHVNCVGTSPEVVDEAFRHAAHVLGLQSD HCCCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure ADDLNPRLAQAHTAESRALNVPNAILPDAWLGMLGGGQLGRMFTHAAQAMGYKVCVLDP CCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECC DPNSPAGTIAERHLCAGYTDEAALAEMAALCPAVTTEFENVPAQALDKLEQLGAFVAPRA CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCH NCVSIAQNRIAEKKFFALCAARTGIHPAPSWVIEHEADIEQLPADLLPGILKIARMGYDG HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHCCHHHHHHHHHHHHCCCCC KGQARVSTIEELRAAWGAMQHVPCVLEKMLPLAYEVSVLAARGADGSTATWPLAENVHRD CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHCCCCC GILFSTIMPSRSVSDDIATRTRAAAAMIAEEMGYVGVLCIEFFVLQDGSLVANEMAPRPH CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCC NSGHITMDVCETSQFEQQVRAMARLPLGSTRQHSPGRMLNVLGDVWFEYGLERTPAWHEV CCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH MGHSGAKVHLYGKADARPGRKMGHVNCVGTSPEVVDEAFRHAAHVLGLQSD HCCCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11756688 [H]