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The map label for this gene is pilE [H]

Identifier: 187927577

GI number: 187927577

Start: 510755

End: 511276

Strand: Direct

Name: pilE [H]

Synonym: Rpic_0477

Alternate gene names: 187927577

Gene position: 510755-511276 (Clockwise)

Preceding gene: 187927576

Following gene: 187927578

Centisome position: 12.95

GC content: 57.85

Gene sequence:

>522_bases
ATGGTTTTCAAGCACAGCAAGGGAATAAAGCGTCGGGCGGGCGGCTTTACGCTGATCGAGCTGATGATTGTGGTGGCGAT
TGTTGGGATTCTCGCGGCGTTGGCGATTCCGGCGTATCAGGACTATACGATTCGGTCGCGGGTGACGGAGGGGCTAATCA
TCGCTGTGCAGGCGAAGGCGCTGGTGGTCGAGAACGCTGCAAACGCACAAAGCAGCCTATCTCTGGGCGCCGCTTCGCTA
TCGGCCACACGAAATGTGGCCTCATTAGACATTGATGGTAGCTCTGGTGAAATTTCCATCGGGTTCACCTCTAGCGTGGC
TGGAGCCGGCAGCAACACGCTAATCCTCACGCCCTACTCAGGCACTGCGTCGTCTACTTACGCGAATCTCAGTGCGGGGT
CGGCTCCTCCAGCAGTCGTCATGTGGGCATGTTCGGCGAATGGCAAGCAAATGCCACCGAACGTCAACCGCACCGGGACG
CCAACTTTGGATGCTCGATATGCTCCGGCGGAGTGCAGATAG

Upstream 100 bases:

>100_bases
AGCAAAGTGCGCCAGTTTGTGCCCAGATACACGATGTATGCCTTGGCATAGTCCCTGCAGGGTGGCCTCTCAACAACAAA
ATACCTTTTGGGGAGAGGTC

Downstream 100 bases:

>100_bases
CGATCCTTGTGCTCAGTCGAGGCGTCTACGCGCGCCGTTTTCGTGTAAGCCGCCGGCCACTGATGACTTTGTGCCAGCTC
CACAAAAATTGACGATACAC

Product: putative type 4 fimbrial pilin signal peptide protein

Products: NA

Alternate protein names: Pilin [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MVFKHSKGIKRRAGGFTLIELMIVVAIVGILAALAIPAYQDYTIRSRVTEGLIIAVQAKALVVENAANAQSSLSLGAASL
SATRNVASLDIDGSSGEISIGFTSSVAGAGSNTLILTPYSGTASSTYANLSAGSAPPAVVMWACSANGKQMPPNVNRTGT
PTLDARYAPAECR

Sequences:

>Translated_173_residues
MVFKHSKGIKRRAGGFTLIELMIVVAIVGILAALAIPAYQDYTIRSRVTEGLIIAVQAKALVVENAANAQSSLSLGAASL
SATRNVASLDIDGSSGEISIGFTSSVAGAGSNTLILTPYSGTASSTYANLSAGSAPPAVVMWACSANGKQMPPNVNRTGT
PTLDARYAPAECR
>Mature_173_residues
MVFKHSKGIKRRAGGFTLIELMIVVAIVGILAALAIPAYQDYTIRSRVTEGLIIAVQAKALVVENAANAQSSLSLGAASL
SATRNVASLDIDGSSGEISIGFTSSVAGAGSNTLILTPYSGTASSTYANLSAGSAPPAVVMWACSANGKQMPPNVNRTGT
PTLDARYAPAECR

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 17673; Mature: 17673

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFKHSKGIKRRAGGFTLIELMIVVAIVGILAALAIPAYQDYTIRSRVTEGLIIAVQAKA
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEEE
LVVENAANAQSSLSLGAASLSATRNVASLDIDGSSGEISIGFTSSVAGAGSNTLILTPYS
EEEECCCCCCHHHHHCHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECC
GTASSTYANLSAGSAPPAVVMWACSANGKQMPPNVNRTGTPTLDARYAPAECR
CCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVFKHSKGIKRRAGGFTLIELMIVVAIVGILAALAIPAYQDYTIRSRVTEGLIIAVQAKA
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEEEEEE
LVVENAANAQSSLSLGAASLSATRNVASLDIDGSSGEISIGFTSSVAGAGSNTLILTPYS
EEEECCCCCCHHHHHCHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEECC
GTASSTYANLSAGSAPPAVVMWACSANGKQMPPNVNRTGTPTLDARYAPAECR
CCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2894335 [H]