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The map label for this gene is obgE

Identifier: 187918634

GI number: 187918634

Start: 831149

End: 832132

Strand: Direct

Name: obgE

Synonym: BH0781

Alternate gene names: 187918634

Gene position: 831149-832132 (Clockwise)

Preceding gene: 187918633

Following gene: 187918635

Centisome position: 90.12

GC content: 36.79

Gene sequence:

>984_bases
TTGCATATACTTAAGGATTCTTTAAGCATAACTGTATCTTCAGGTGATGGGGGTGCAGGGTGTGTTTCTTTTTTGCGTGA
AAGATTTAATACCAAGGGAGGTCCTGATGGCGGTGATGGAGGAAGAGGTGGAGATGTAATCTTTAAGGTTAAGGCAAATC
TTAAAAGTTTATCCCTTTATAAAAATGGCCAAAGACTTGCTGCTAATAATGGTAAGCCCGGAATGGGTTCTAGAAAGAGT
GGAGCATCTGGTGAAGATTTGGTTATTTTTGTTCCCCCAAATACTTGTATTTATGATGTTGCAACAGGCTCTATGTTATT
TGAGCTCCAGAACTTTGATGATGAAGTTATTGCTTTAAAGGGCGGAAGAGGTGGACTTGGGAATGTACATTTTAAAAGTT
CTACAAAACGGACACCAAGATTTGCTCAGCCTGGAGAATCTGGCGCTACCTTGAATTTGCGTCTTGAGTTATCATTAATA
GCCGATATTGGACTTGTTGGGTTTCCTAATGCAGGTAAGTCTTCTCTTATTTCTACAATAACCGCTTCAAAGTCAAGAGT
TGCAAATTATCCTTTTACTACTAGATTTCCGCATCTTGGCGTTTTGAAGGCTTCTTATAATGATTTGGTAATCGCTGATG
TGCCCGGGCTAATTGAGGGCGCAAGTCAAGGAATAGGTCTTGGTTTTGAATTTTTAAGACATATTTCAAAAACCAAAATC
CTGGTCTTTTTAATTGATGTTGCTAGTGATAACTTTATGAGTGCTTATGATATTCTTGTTAATGAGCTTAGTGCATATGA
TATTGGACTTTCAAGTAAGAAGCGAATAATTGTTGCTAATAAACTTGATTTAGAAGGTGCGATTGAAAATTTTAATCAGC
TAAAGAGAGCTTTAGTTGGTGAGAGAGTTTTAGGAATTTCTATTTATGATAATACGGGAATAAATGAGCTTGTTAGTGAG
CTTTTTGCTTTATCAAGAATTTAA

Upstream 100 bases:

>100_bases
TATACAATATTTGCATTAAAAGATGGTATAGTAGAGTTTAAGACTTATAGAGGCCGAAAATATATAAATATTATTTAATA
TTGTTATAGTTGAGGTTAAT

Downstream 100 bases:

>100_bases
GGAGATTATTTTTTCTTTTTTAAAAGCTCAAAATTAACAATATTGTTAAGGCTTTAATTAGTATATTGTCAGTATATAAT
ATGGGAGGTTTATGCGAATA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MHILKDSLSITVSSGDGGAGCVSFLRERFNTKGGPDGGDGGRGGDVIFKVKANLKSLSLYKNGQRLAANNGKPGMGSRKS
GASGEDLVIFVPPNTCIYDVATGSMLFELQNFDDEVIALKGGRGGLGNVHFKSSTKRTPRFAQPGESGATLNLRLELSLI
ADIGLVGFPNAGKSSLISTITASKSRVANYPFTTRFPHLGVLKASYNDLVIADVPGLIEGASQGIGLGFEFLRHISKTKI
LVFLIDVASDNFMSAYDILVNELSAYDIGLSSKKRIIVANKLDLEGAIENFNQLKRALVGERVLGISIYDNTGINELVSE
LFALSRI

Sequences:

>Translated_327_residues
MHILKDSLSITVSSGDGGAGCVSFLRERFNTKGGPDGGDGGRGGDVIFKVKANLKSLSLYKNGQRLAANNGKPGMGSRKS
GASGEDLVIFVPPNTCIYDVATGSMLFELQNFDDEVIALKGGRGGLGNVHFKSSTKRTPRFAQPGESGATLNLRLELSLI
ADIGLVGFPNAGKSSLISTITASKSRVANYPFTTRFPHLGVLKASYNDLVIADVPGLIEGASQGIGLGFEFLRHISKTKI
LVFLIDVASDNFMSAYDILVNELSAYDIGLSSKKRIIVANKLDLEGAIENFNQLKRALVGERVLGISIYDNTGINELVSE
LFALSRI
>Mature_327_residues
MHILKDSLSITVSSGDGGAGCVSFLRERFNTKGGPDGGDGGRGGDVIFKVKANLKSLSLYKNGQRLAANNGKPGMGSRKS
GASGEDLVIFVPPNTCIYDVATGSMLFELQNFDDEVIALKGGRGGLGNVHFKSSTKRTPRFAQPGESGATLNLRLELSLI
ADIGLVGFPNAGKSSLISTITASKSRVANYPFTTRFPHLGVLKASYNDLVIADVPGLIEGASQGIGLGFEFLRHISKTKI
LVFLIDVASDNFMSAYDILVNELSAYDIGLSSKKRIIVANKLDLEGAIENFNQLKRALVGERVLGISIYDNTGINELVSE
LFALSRI

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=320, Percent_Identity=40.3125, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI111955139, Length=263, Percent_Identity=34.2205323193916, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI111955063, Length=141, Percent_Identity=37.5886524822695, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4758796, Length=113, Percent_Identity=36.283185840708, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI4557537, Length=114, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789574, Length=295, Percent_Identity=43.728813559322, Blast_Score=197, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17508313, Length=319, Percent_Identity=38.2445141065831, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=332, Percent_Identity=28.0120481927711, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71981008, Length=113, Percent_Identity=34.5132743362832, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=162, Percent_Identity=37.037037037037, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321612, Length=150, Percent_Identity=32, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=88, Percent_Identity=36.3636363636364, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=319, Percent_Identity=38.5579937304075, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24585318, Length=244, Percent_Identity=37.7049180327869, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21356473, Length=114, Percent_Identity=34.2105263157895, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BORHD (B2S1C3)

Other databases:

- EMBL:   CP000048
- RefSeq:   YP_001884199.1
- EnsemblBacteria:   EBBORT00000006947
- GeneID:   6277109
- GenomeReviews:   CP000048_GR
- KEGG:   bhr:BH0781
- GeneTree:   EBGT00050000006860
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   BHER314723:BH0781-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 34805; Mature: 34805

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILKDSLSITVSSGDGGAGCVSFLRERFNTKGGPDGGDGGRGGDVIFKVKANLKSLSLY
CCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEE
KNGQRLAANNGKPGMGSRKSGASGEDLVIFVPPNTCIYDVATGSMLFELQNFDDEVIALK
CCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEECCCCCEEEEEE
GGRGGLGNVHFKSSTKRTPRFAQPGESGATLNLRLELSLIADIGLVGFPNAGKSSLISTI
CCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHH
TASKSRVANYPFTTRFPHLGVLKASYNDLVIADVPGLIEGASQGIGLGFEFLRHISKTKI
HHCHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCHHHHCCCCCCCHHHHHHHHHCCCEE
LVFLIDVASDNFMSAYDILVNELSAYDIGLSSKKRIIVANKLDLEGAIENFNQLKRALVG
EEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHC
ERVLGISIYDNTGINELVSELFALSRI
CEEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MHILKDSLSITVSSGDGGAGCVSFLRERFNTKGGPDGGDGGRGGDVIFKVKANLKSLSLY
CCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEE
KNGQRLAANNGKPGMGSRKSGASGEDLVIFVPPNTCIYDVATGSMLFELQNFDDEVIALK
CCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEEEEECCCCCEEEEEE
GGRGGLGNVHFKSSTKRTPRFAQPGESGATLNLRLELSLIADIGLVGFPNAGKSSLISTI
CCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHH
TASKSRVANYPFTTRFPHLGVLKASYNDLVIADVPGLIEGASQGIGLGFEFLRHISKTKI
HHCHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCHHHHCCCCCCCHHHHHHHHHCCCEE
LVFLIDVASDNFMSAYDILVNELSAYDIGLSSKKRIIVANKLDLEGAIENFNQLKRALVG
EEEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHC
ERVLGISIYDNTGINELVSELFALSRI
CEEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA