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The map label for this gene is lolC [H]

Identifier: 187917959

GI number: 187917959

Start: 76087

End: 77337

Strand: Direct

Name: lolC [H]

Synonym: BH0081

Alternate gene names: 187917959

Gene position: 76087-77337 (Clockwise)

Preceding gene: 187917958

Following gene: 187917962

Centisome position: 8.25

GC content: 24.3

Gene sequence:

>1251_bases
ATGATGCGTCCAAATACTAAAGAACTCACAAAAATAGCATACATAATATTTACAAATTCAAAAAATAAAAAAGCCCTAAT
TGGTTCTGGAATATCTTTAAGTTTAGTCATGATTCCTTTAATTATTGTTTACTACATGTCAAACAACATCATGAATTCCA
CAATAGATAAATACATTGAAAATGAAGGATTCTCGGTACAAATCGAATATAATGAAATTCAAAAAGATACTCATCTTAGA
TCTAAACTAGAAAAATTTAAAAAAGAATATCAACATGATGAACTAAAATATTTTTTTGAAAGAAGAACCTATGGAATAAT
TGGAAATCAAAAAAAACAAGGGGTATTAATAAGGGCAGTAGAAGACAAATTTATTGATGAAAATAAACATATAAAATTAA
TAGATGGCAAGAAGAGCTTCAACAAAAACGAAATATTAATATCAAAACAAATAAGAGACAGACTTAATTTAAACATCAAT
GAATCTATTTATATAGTAGTACCAAATAATAAGCATCAAAAGATATTCCCTAGGGCAAAGAAATTCAATATATCTGGAAT
CATTGAAACGGGTTTAAGGGAAGTTGATAAAAACTTAGTTCTTATTTCATTACAAGACGCAAATATAATGTCGGAAGAAT
TTTCTAAAAGTATAATTGGAATCTCTGTCAAACCCAATACCAAAGAAAAAGCGAATAATTTAAAGAAAAACATTGCAAAA
GAATTTCAAAAATATAAAATAAAAACATTCTATGAGCTTTATTTAAACAAATATAAAAACTTAGATATCAGCAAAAAACT
CTTAATATTTATTATGGCATTTATTGTAATATTTGCAAGCATTAATATATCCTCATCTCTTTGCATGTTAATACTTGAGA
ATAAAAAGAAAATTGCAATATTTAAATCAATTGGAATGAATAATTCAAGTATTAAGCTAATATTTATATTAATAGCACTC
GTTCTAAGCTCAATATCTTGCTTAATAGGCATAATCATTGGAAATTACATAACCATTAATATAGAACATTTAATTAATAT
AATAGACATTATTATTAATACAATTTTAAAAATATTTGGAGCTGATAATACAGAACTTTTAAACTCTGATTATTATATCT
CTGAATTTAATATTAAAATAAGCACCAAATTTAGCTTAATTATTCTTTTATCCTACACACTAATTAGTGTCGCAACAACG
CTTATTCCCCTAAATATTATTTCAAAGCTTAAAGAAAAAGAAATTTTATAG

Upstream 100 bases:

>100_bases
AAACATTTAATAAAACACTAATTTTAGTTAGTCACAATCCAGAATTTTCAAATAAAGCAGATATTAAATATGAACTTAAA
GACAAAACACTAAAGAGAAT

Downstream 100 bases:

>100_bases
ATAAATCAATATCTCTTCTCTATACACAAAAATACTATTTTGCAAACACATTTACGATCTTAATAGAAGATAGCTCTTCT
TTAATATTTGGATAAATCTC

Product: lipoprotein releasing system transmembrane protein LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MMRPNTKELTKIAYIIFTNSKNKKALIGSGISLSLVMIPLIIVYYMSNNIMNSTIDKYIENEGFSVQIEYNEIQKDTHLR
SKLEKFKKEYQHDELKYFFERRTYGIIGNQKKQGVLIRAVEDKFIDENKHIKLIDGKKSFNKNEILISKQIRDRLNLNIN
ESIYIVVPNNKHQKIFPRAKKFNISGIIETGLREVDKNLVLISLQDANIMSEEFSKSIIGISVKPNTKEKANNLKKNIAK
EFQKYKIKTFYELYLNKYKNLDISKKLLIFIMAFIVIFASINISSSLCMLILENKKKIAIFKSIGMNNSSIKLIFILIAL
VLSSISCLIGIIIGNYITINIEHLINIIDIIINTILKIFGADNTELLNSDYYISEFNIKISTKFSLIILLSYTLISVATT
LIPLNIISKLKEKEIL

Sequences:

>Translated_416_residues
MMRPNTKELTKIAYIIFTNSKNKKALIGSGISLSLVMIPLIIVYYMSNNIMNSTIDKYIENEGFSVQIEYNEIQKDTHLR
SKLEKFKKEYQHDELKYFFERRTYGIIGNQKKQGVLIRAVEDKFIDENKHIKLIDGKKSFNKNEILISKQIRDRLNLNIN
ESIYIVVPNNKHQKIFPRAKKFNISGIIETGLREVDKNLVLISLQDANIMSEEFSKSIIGISVKPNTKEKANNLKKNIAK
EFQKYKIKTFYELYLNKYKNLDISKKLLIFIMAFIVIFASINISSSLCMLILENKKKIAIFKSIGMNNSSIKLIFILIAL
VLSSISCLIGIIIGNYITINIEHLINIIDIIINTILKIFGADNTELLNSDYYISEFNIKISTKFSLIILLSYTLISVATT
LIPLNIISKLKEKEIL
>Mature_416_residues
MMRPNTKELTKIAYIIFTNSKNKKALIGSGISLSLVMIPLIIVYYMSNNIMNSTIDKYIENEGFSVQIEYNEIQKDTHLR
SKLEKFKKEYQHDELKYFFERRTYGIIGNQKKQGVLIRAVEDKFIDENKHIKLIDGKKSFNKNEILISKQIRDRLNLNIN
ESIYIVVPNNKHQKIFPRAKKFNISGIIETGLREVDKNLVLISLQDANIMSEEFSKSIIGISVKPNTKEKANNLKKNIAK
EFQKYKIKTFYELYLNKYKNLDISKKLLIFIMAFIVIFASINISSSLCMLILENKKKIAIFKSIGMNNSSIKLIFILIAL
VLSSISCLIGIIIGNYITINIEHLINIIDIIINTILKIFGADNTELLNSDYYISEFNIKISTKFSLIILLSYTLISVATT
LIPLNIISKLKEKEIL

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=278, Percent_Identity=23.021582733813, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47933; Mature: 47933

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRPNTKELTKIAYIIFTNSKNKKALIGSGISLSLVMIPLIIVYYMSNNIMNSTIDKYIE
CCCCCHHHHEEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NEGFSVQIEYNEIQKDTHLRSKLEKFKKEYQHDELKYFFERRTYGIIGNQKKQGVLIRAV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
EDKFIDENKHIKLIDGKKSFNKNEILISKQIRDRLNLNINESIYIVVPNNKHQKIFPRAK
CHHHCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
KFNISGIIETGLREVDKNLVLISLQDANIMSEEFSKSIIGISVKPNTKEKANNLKKNIAK
EECCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
EFQKYKIKTFYELYLNKYKNLDISKKLLIFIMAFIVIFASINISSSLCMLILENKKKIAI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
FKSIGMNNSSIKLIFILIALVLSSISCLIGIIIGNYITINIEHLINIIDIIINTILKIFG
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHC
ADNTELLNSDYYISEFNIKISTKFSLIILLSYTLISVATTLIPLNIISKLKEKEIL
CCCCCEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRPNTKELTKIAYIIFTNSKNKKALIGSGISLSLVMIPLIIVYYMSNNIMNSTIDKYIE
CCCCCHHHHEEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NEGFSVQIEYNEIQKDTHLRSKLEKFKKEYQHDELKYFFERRTYGIIGNQKKQGVLIRAV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
EDKFIDENKHIKLIDGKKSFNKNEILISKQIRDRLNLNINESIYIVVPNNKHQKIFPRAK
CHHHCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
KFNISGIIETGLREVDKNLVLISLQDANIMSEEFSKSIIGISVKPNTKEKANNLKKNIAK
EECCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHH
EFQKYKIKTFYELYLNKYKNLDISKKLLIFIMAFIVIFASINISSSLCMLILENKKKIAI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEE
FKSIGMNNSSIKLIFILIALVLSSISCLIGIIIGNYITINIEHLINIIDIIINTILKIFG
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHC
ADNTELLNSDYYISEFNIKISTKFSLIILLSYTLISVATTLIPLNIISKLKEKEIL
CCCCCEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]