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The map label for this gene is argA [H]

Identifier: 187736654

GI number: 187736654

Start: 2662856

End: 2663914

Strand: Direct

Name: argA [H]

Synonym: Amuc_2178

Alternate gene names: 187736654

Gene position: 2662856-2663914 (Clockwise)

Preceding gene: 187736653

Following gene: NA

Centisome position: 99.95

GC content: 58.55

Gene sequence:

>1059_bases
GTGCTGGAGTATGTTCCGTACTTCAGGGATAAAATCTTTGCCGTGCACGTGGAACGCCCCCTGGTGGATTCCGGGGAATT
GGTGGATGCCCTGCTGGACTTGGACGTACTGCAGGAAATAGGCGTCAGGCCCGTTCTGATTGTGGAAGGGGCGGACGCCT
CCGCGCTGTACGAACACACGCGCGTCTGTGAAATGCGCTCCGCCCTGGTGGAAGCGCCATTGAAGGGCGGCCAGCTTGTC
CGGGAAAGAGTCCGGGAAATTCTGGGGCGTCACCAAATTCCCGTGGTGGCTTCCGGCCGTTCCGGCTCCTTTGACCCGGA
ATCCGTCCATATGGCCTTCAGTCTGGGGGCCTCCAAATACATCGCCCTGCTCAATGACCACAAGGTTCCGTCCCTGGACG
GACGCCCCATTGCCGCCATTCTGGAATCGGAAGTAGCGGAGCTGGCAGGAAACGTAACCCACCGCGAACTGCTTGACCAG
GCAGCGGAAGCCTGCCGGGCGGGAATCCCCCGCGTGCATCTGCTGGACGGAAAAATGCGCGGCGTGCTGGTGGAGGAACT
CTTCTCTGAAGAAGGCGTAGGAACCATGGTCCACACGGACTCCTACCGGGAAATACGCCCGCTGAAGGAAGAAGACATTC
CGGAACTCCTCTCCATGATCGCCCGTTCCGTAGTGGACTCCAAATTGGTCAACCGGAACTATGAAGACATTGCCGCCAGA
ATAGACAGTTACTACGTGCTGACCCTGGACGACAGCATCGTGGGCTGCGTTGCCGTTTATCCCTACCCGGAGCACCATAG
CGCAGAACTGGGCTGCCTGTACATCAAGCACCGCCATGAAGGCCGCGGCTATGGCCGCGCACTATGTGAATTTGCCAAAA
GAAAAGCGGAGGAAATGGGAATGGAATTCATCTTTGCCCTCTCCCAAAGCGCCGTCCATTACTTCCGGGACCGCATGCAT
TACGCGGAATTTTCCCGCGACAGCCTGCCCCCGGAACGCCTGCGTACTCTGGAACTCAGCGGGCGCAAATCCGGGGTTTT
CGGGTTAAGGCTGAAATAG

Upstream 100 bases:

>100_bases
ACAAGGCCGGGGGAAACGGGAATGTCCGTTTGCCCCGGCCCCAAACTTCCGGTCCGCCTTGGCTACGCTCCCTCCCAACA
AATCCGCCAATGTCCGTTCC

Downstream 100 bases:

>100_bases
TTTTCTATTTACCTCTCTGCCCCGTTCCTGCTTATGGGCGGAATCCCCTGCACCAAATGGACGGGTAGCTATTCCCGTCT
CTCGTTAAAGGGTATATAGT

Product: Amino-acid N-acetyltransferase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLEYVPYFRDKIFAVHVERPLVDSGELVDALLDLDVLQEIGVRPVLIVEGADASALYEHTRVCEMRSALVEAPLKGGQLV
RERVREILGRHQIPVVASGRSGSFDPESVHMAFSLGASKYIALLNDHKVPSLDGRPIAAILESEVAELAGNVTHRELLDQ
AAEACRAGIPRVHLLDGKMRGVLVEELFSEEGVGTMVHTDSYREIRPLKEEDIPELLSMIARSVVDSKLVNRNYEDIAAR
IDSYYVLTLDDSIVGCVAVYPYPEHHSAELGCLYIKHRHEGRGYGRALCEFAKRKAEEMGMEFIFALSQSAVHYFRDRMH
YAEFSRDSLPPERLRTLELSGRKSGVFGLRLK

Sequences:

>Translated_352_residues
MLEYVPYFRDKIFAVHVERPLVDSGELVDALLDLDVLQEIGVRPVLIVEGADASALYEHTRVCEMRSALVEAPLKGGQLV
RERVREILGRHQIPVVASGRSGSFDPESVHMAFSLGASKYIALLNDHKVPSLDGRPIAAILESEVAELAGNVTHRELLDQ
AAEACRAGIPRVHLLDGKMRGVLVEELFSEEGVGTMVHTDSYREIRPLKEEDIPELLSMIARSVVDSKLVNRNYEDIAAR
IDSYYVLTLDDSIVGCVAVYPYPEHHSAELGCLYIKHRHEGRGYGRALCEFAKRKAEEMGMEFIFALSQSAVHYFRDRMH
YAEFSRDSLPPERLRTLELSGRKSGVFGLRLK
>Mature_352_residues
MLEYVPYFRDKIFAVHVERPLVDSGELVDALLDLDVLQEIGVRPVLIVEGADASALYEHTRVCEMRSALVEAPLKGGQLV
RERVREILGRHQIPVVASGRSGSFDPESVHMAFSLGASKYIALLNDHKVPSLDGRPIAAILESEVAELAGNVTHRELLDQ
AAEACRAGIPRVHLLDGKMRGVLVEELFSEEGVGTMVHTDSYREIRPLKEEDIPELLSMIARSVVDSKLVNRNYEDIAAR
IDSYYVLTLDDSIVGCVAVYPYPEHHSAELGCLYIKHRHEGRGYGRALCEFAKRKAEEMGMEFIFALSQSAVHYFRDRMH
YAEFSRDSLPPERLRTLELSGRKSGVFGLRLK

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG1246

COG function: function code E; N-acetylglutamate synthase and related acetyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=266, Percent_Identity=28.9473684210526, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 39470; Mature: 39470

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYVPYFRDKIFAVHVERPLVDSGELVDALLDLDVLQEIGVRPVLIVEGADASALYEHT
CCCCCCCHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
RVCEMRSALVEAPLKGGQLVRERVREILGRHQIPVVASGRSGSFDPESVHMAFSLGASKY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHEEEEEECCCHHE
IALLNDHKVPSLDGRPIAAILESEVAELAGNVTHRELLDQAAEACRAGIPRVHLLDGKMR
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCHHH
GVLVEELFSEEGVGTMVHTDSYREIRPLKEEDIPELLSMIARSVVDSKLVNRNYEDIAAR
HHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IDSYYVLTLDDSIVGCVAVYPYPEHHSAELGCLYIKHRHEGRGYGRALCEFAKRKAEEMG
HCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MEFIFALSQSAVHYFRDRMHYAEFSRDSLPPERLRTLELSGRKSGVFGLRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCEEEEEEC
>Mature Secondary Structure
MLEYVPYFRDKIFAVHVERPLVDSGELVDALLDLDVLQEIGVRPVLIVEGADASALYEHT
CCCCCCCHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
RVCEMRSALVEAPLKGGQLVRERVREILGRHQIPVVASGRSGSFDPESVHMAFSLGASKY
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHEEEEEECCCHHE
IALLNDHKVPSLDGRPIAAILESEVAELAGNVTHRELLDQAAEACRAGIPRVHLLDGKMR
EEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCHHH
GVLVEELFSEEGVGTMVHTDSYREIRPLKEEDIPELLSMIARSVVDSKLVNRNYEDIAAR
HHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IDSYYVLTLDDSIVGCVAVYPYPEHHSAELGCLYIKHRHEGRGYGRALCEFAKRKAEEMG
HCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
MEFIFALSQSAVHYFRDRMHYAEFSRDSLPPERLRTLELSGRKSGVFGLRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA