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The map label for this gene is argS [H]

Identifier: 187736645

GI number: 187736645

Start: 2646702

End: 2648459

Strand: Reverse

Name: argS [H]

Synonym: Amuc_2169

Alternate gene names: 187736645

Gene position: 2648459-2646702 (Counterclockwise)

Preceding gene: 187736646

Following gene: 187736644

Centisome position: 99.41

GC content: 61.55

Gene sequence:

>1758_bases
ATGACCATACCCGGAATTCTTGAAGAAAAGTTGTCCTCCGCATTAAAGGCGGTGTTGGGGGAGGAGCTTCCCGCTGATTT
TCGCGCCTCGGTGACGCCCTCCGCGGATTTGCGGTTCGGGGATTACCAGAGCAACGCCGCCATGGTGCTTGCCAAGCGGT
GCCGCACGAATCCCCGCGCGCTCGCCCAGCAGGTGGCGGACCGGATAGGGCAGGATGCCGTGTGCTCCCTGGAAATTGCC
GGGCCCGGATTCATCAATTTCCGCATCAGGCCGGAATTTTACGCAGCGCGCCTGCTGGCCATGCTGGCGGATGACCGGCT
GGGGGTGGAAAAAGTGCAGGCCCCCAAAACCATTGTCATTGACTTTTCCGCTCCCAACGTCGCCAAGCCGATGCATGTGG
GCCACATCCGCTCCACCATTATTGGTGACGCCCTTTCCCGCGTGGCCCGTTTTGTGGGGCACCATGTGATTACGGACAAC
CACATCGGGGACTGGGGTACCCAGTTCGGCATGATCCTGTGGGGCTGGAAGAATATTCTGGATGAGCAGGCCCTGGCCGC
CAACCCTATTGACGAGCTGCTGCGGGTGTACAAGGATGTGAACCTGATGTGCAAGGAAAAGCCGGAACTGCTGGATACCT
GCAAGGCGGAACTGGTGAAGCTCCAGGCCGGGGACGGGGAAAACCTGGCCATCTGGAAACGCTGCGTGGAAGTTTCCAAA
TCCGGCCTTTCCAAAATTTACGACCAGCTTGACATCCATTTTGATTACTGGCTGGGGGAAAGCTTTTACAATGATGCCCT
GGCCCCGCTGGTGGACGGCATGATCGCCGCCGGAATGGCCCGGGAGAGCGACGGGGCCATCTGCGTGTTTTCCGACGGTT
CCGTGCCGCCCAATGAAGACCCCTTCCTCGTGCAGGACAAGGGGGAATGGCGCGCCAACCCCTGCATCATCAGGAAAGCG
GACGGAGGCTTCCTGTACGCCACCACGGACCTCGCGACGCTGGACCACCGCATCAGGACGTGGGGCGCGGATTCCATCTG
GTACGTGGTGGGCGCCCCTCAGGCCCTGCATTTCAGGCAGATTTTCTCCACGCAGCGCCGCCGCGGCATGGACGGGGACT
ACCGGCACATTGCGTTCGGCTCCATTCTGGGTGACGACCGCAAGCCGTTTAAGACGCGTTCCGGGGATACGGTTTCCCTC
CAGGATGTGCTGGATGAAGCCATTGAACGCGCGGCCCGCGTGGTGGAGGAGAAGAGCCCGGACATGCCGGATGAGGAAAA
GAAGCGCGTGGCGGAAGTTGTGGGCATAGGCGCCGTGAAGTTTGCGGAGCTGTCCCAGAACCGCATGACGGATTACGTTT
TCAACTGGGACAAGATGCTGGCTCTTCAGGGAGATACGGCGCCGTACCTCCAGAACTCCTACGTGCGCGTCCGCTCCATC
TTCCGCAAGCTGGACGGCGGGCCTTTGGACTGGTCCGCCCCCATTCAGCTTTCAGAAGATGCGGAAATCCATCTGGCCCG
GCTTCTGGCCCGCTACGGGGAAGTGGTGCCGCAGGTGCTGGACGACTGCCGTCCGAACGTGCTGGCCGCCTACCTGTTTG
ACCTGGCCAGGGCTTTCCATTCCTTCTATGAGGCGTGCCCGGTCCTGAAGTCGGAGGGGCCGGTGCGGCACTCCCGCCTG
GCCCTGTGCGAGCTGACCGCACGCACGCTGAAGCACGGGCTGGGCCTGCTGGGCATCCAGCTTCCGGACAGGATGTAA

Upstream 100 bases:

>100_bases
GGATGTTATCTCCGTCCTGTTGTTTTTACCGGAAAAGGTATGTCTTGATGACAGTTGCGCCTTGACTACGGCGGTGGAAT
GTCCGTTCATCTGGGCAGAC

Downstream 100 bases:

>100_bases
CCGTTTCTTCCGTATGGACGCCTCTTTCCTCCATGTCCTGCTGGCCGCCGCCGTGGCGGGGTGTTCTTCCGCCGCCGCGG
ACGGGGCACACGGGTATTGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MTIPGILEEKLSSALKAVLGEELPADFRASVTPSADLRFGDYQSNAAMVLAKRCRTNPRALAQQVADRIGQDAVCSLEIA
GPGFINFRIRPEFYAARLLAMLADDRLGVEKVQAPKTIVIDFSAPNVAKPMHVGHIRSTIIGDALSRVARFVGHHVITDN
HIGDWGTQFGMILWGWKNILDEQALAANPIDELLRVYKDVNLMCKEKPELLDTCKAELVKLQAGDGENLAIWKRCVEVSK
SGLSKIYDQLDIHFDYWLGESFYNDALAPLVDGMIAAGMARESDGAICVFSDGSVPPNEDPFLVQDKGEWRANPCIIRKA
DGGFLYATTDLATLDHRIRTWGADSIWYVVGAPQALHFRQIFSTQRRRGMDGDYRHIAFGSILGDDRKPFKTRSGDTVSL
QDVLDEAIERAARVVEEKSPDMPDEEKKRVAEVVGIGAVKFAELSQNRMTDYVFNWDKMLALQGDTAPYLQNSYVRVRSI
FRKLDGGPLDWSAPIQLSEDAEIHLARLLARYGEVVPQVLDDCRPNVLAAYLFDLARAFHSFYEACPVLKSEGPVRHSRL
ALCELTARTLKHGLGLLGIQLPDRM

Sequences:

>Translated_585_residues
MTIPGILEEKLSSALKAVLGEELPADFRASVTPSADLRFGDYQSNAAMVLAKRCRTNPRALAQQVADRIGQDAVCSLEIA
GPGFINFRIRPEFYAARLLAMLADDRLGVEKVQAPKTIVIDFSAPNVAKPMHVGHIRSTIIGDALSRVARFVGHHVITDN
HIGDWGTQFGMILWGWKNILDEQALAANPIDELLRVYKDVNLMCKEKPELLDTCKAELVKLQAGDGENLAIWKRCVEVSK
SGLSKIYDQLDIHFDYWLGESFYNDALAPLVDGMIAAGMARESDGAICVFSDGSVPPNEDPFLVQDKGEWRANPCIIRKA
DGGFLYATTDLATLDHRIRTWGADSIWYVVGAPQALHFRQIFSTQRRRGMDGDYRHIAFGSILGDDRKPFKTRSGDTVSL
QDVLDEAIERAARVVEEKSPDMPDEEKKRVAEVVGIGAVKFAELSQNRMTDYVFNWDKMLALQGDTAPYLQNSYVRVRSI
FRKLDGGPLDWSAPIQLSEDAEIHLARLLARYGEVVPQVLDDCRPNVLAAYLFDLARAFHSFYEACPVLKSEGPVRHSRL
ALCELTARTLKHGLGLLGIQLPDRM
>Mature_584_residues
TIPGILEEKLSSALKAVLGEELPADFRASVTPSADLRFGDYQSNAAMVLAKRCRTNPRALAQQVADRIGQDAVCSLEIAG
PGFINFRIRPEFYAARLLAMLADDRLGVEKVQAPKTIVIDFSAPNVAKPMHVGHIRSTIIGDALSRVARFVGHHVITDNH
IGDWGTQFGMILWGWKNILDEQALAANPIDELLRVYKDVNLMCKEKPELLDTCKAELVKLQAGDGENLAIWKRCVEVSKS
GLSKIYDQLDIHFDYWLGESFYNDALAPLVDGMIAAGMARESDGAICVFSDGSVPPNEDPFLVQDKGEWRANPCIIRKAD
GGFLYATTDLATLDHRIRTWGADSIWYVVGAPQALHFRQIFSTQRRRGMDGDYRHIAFGSILGDDRKPFKTRSGDTVSLQ
DVLDEAIERAARVVEEKSPDMPDEEKKRVAEVVGIGAVKFAELSQNRMTDYVFNWDKMLALQGDTAPYLQNSYVRVRSIF
RKLDGGPLDWSAPIQLSEDAEIHLARLLARYGEVVPQVLDDCRPNVLAAYLFDLARAFHSFYEACPVLKSEGPVRHSRLA
LCELTARTLKHGLGLLGIQLPDRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=586, Percent_Identity=36.1774744027304, Blast_Score=348, Evalue=1e-95,
Organism=Homo sapiens, GI197100773, Length=572, Percent_Identity=28.8461538461538, Blast_Score=244, Evalue=1e-64,
Organism=Escherichia coli, GI1788184, Length=594, Percent_Identity=44.2760942760943, Blast_Score=467, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI71985061, Length=602, Percent_Identity=34.3853820598007, Blast_Score=315, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI71985068, Length=570, Percent_Identity=34.5614035087719, Blast_Score=299, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17532153, Length=498, Percent_Identity=27.710843373494, Blast_Score=156, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320548, Length=546, Percent_Identity=31.3186813186813, Blast_Score=253, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6321883, Length=501, Percent_Identity=30.7385229540918, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI18859963, Length=609, Percent_Identity=32.512315270936, Blast_Score=311, Evalue=9e-85,
Organism=Drosophila melanogaster, GI28571570, Length=520, Percent_Identity=30.5769230769231, Blast_Score=211, Evalue=1e-54,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65097; Mature: 64966

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPGILEEKLSSALKAVLGEELPADFRASVTPSADLRFGDYQSNAAMVLAKRCRTNPRA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCHHH
LAQQVADRIGQDAVCSLEIAGPGFINFRIRPEFYAARLLAMLADDRLGVEKVQAPKTIVI
HHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHCCCCEEEE
DFSAPNVAKPMHVGHIRSTIIGDALSRVARFVGHHVITDNHIGDWGTQFGMILWGWKNIL
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHH
DEQALAANPIDELLRVYKDVNLMCKEKPELLDTCKAELVKLQAGDGENLAIWKRCVEVSK
HHHHHCCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHH
SGLSKIYDQLDIHFDYWLGESFYNDALAPLVDGMIAAGMARESDGAICVFSDGSVPPNED
HHHHHHHHHHCCEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
PFLVQDKGEWRANPCIIRKADGGFLYATTDLATLDHRIRTWGADSIWYVVGAPQALHFRQ
CEEEECCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
IFSTQRRRGMDGDYRHIAFGSILGDDRKPFKTRSGDTVSLQDVLDEAIERAARVVEEKSP
HHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCC
DMPDEEKKRVAEVVGIGAVKFAELSQNRMTDYVFNWDKMLALQGDTAPYLQNSYVRVRSI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
FRKLDGGPLDWSAPIQLSEDAEIHLARLLARYGEVVPQVLDDCRPNVLAAYLFDLARAFH
HHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SFYEACPVLKSEGPVRHSRLALCELTARTLKHGLGLLGIQLPDRM
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure 
TIPGILEEKLSSALKAVLGEELPADFRASVTPSADLRFGDYQSNAAMVLAKRCRTNPRA
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCHHH
LAQQVADRIGQDAVCSLEIAGPGFINFRIRPEFYAARLLAMLADDRLGVEKVQAPKTIVI
HHHHHHHHCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHCCCCEEEE
DFSAPNVAKPMHVGHIRSTIIGDALSRVARFVGHHVITDNHIGDWGTQFGMILWGWKNIL
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHH
DEQALAANPIDELLRVYKDVNLMCKEKPELLDTCKAELVKLQAGDGENLAIWKRCVEVSK
HHHHHCCCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHH
SGLSKIYDQLDIHFDYWLGESFYNDALAPLVDGMIAAGMARESDGAICVFSDGSVPPNED
HHHHHHHHHHCCEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
PFLVQDKGEWRANPCIIRKADGGFLYATTDLATLDHRIRTWGADSIWYVVGAPQALHFRQ
CEEEECCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCCCCEEEEECCCHHHHHHH
IFSTQRRRGMDGDYRHIAFGSILGDDRKPFKTRSGDTVSLQDVLDEAIERAARVVEEKSP
HHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCC
DMPDEEKKRVAEVVGIGAVKFAELSQNRMTDYVFNWDKMLALQGDTAPYLQNSYVRVRSI
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH
FRKLDGGPLDWSAPIQLSEDAEIHLARLLARYGEVVPQVLDDCRPNVLAAYLFDLARAFH
HHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SFYEACPVLKSEGPVRHSRLALCELTARTLKHGLGLLGIQLPDRM
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA