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The map label for this gene is nuoC2 [H]

Identifier: 187736634

GI number: 187736634

Start: 2630068

End: 2630652

Strand: Direct

Name: nuoC2 [H]

Synonym: Amuc_2158

Alternate gene names: 187736634

Gene position: 2630068-2630652 (Clockwise)

Preceding gene: 187736633

Following gene: 187736635

Centisome position: 98.72

GC content: 56.24

Gene sequence:

>585_bases
ATGCTTTCTCTAGAATCACAGATTAAAACCGCCGCAGACAACGCCCAAAACCGCTTTGGGAAAGACATCATCACGGACCG
CTACGAATTCCGCGGAGATATTACGCTGACCGTCGCGCGCCAAGCCGTGGCGGATGTTGTCCGCTGGCTACGGGATTCCG
CCGGGTTTGATATGCTGGTTAACCTTTCTTCCGTGGACAATATGGGGGAAAGCCCCCGCTTTGAAGTCAACTACACGCTG
ACACAGTCGGAAACGGGAGCGAACCTGAGCCTCAAGACGAAGGTGGACGATGGCGAAGAAGTGCCCAGCGTCACGGAAAT
TTTCCAGTCCGCCAACTGGCACGAACGTGAAGCATGGGACCTGATGGGCATCAAGTTCTCAGGTCATCCTGATTTGCGCC
GCATTTTGATGTGGGAAGGTTATCCTTATTTCCCTCTGCGAAAGGATTTCCCTGTTCAAGGCGTACCTACTGAACTGCCG
GGCGTCGCCTTTACGGAGGCGGCTCCCACCCAGGGAGCGCCGTTCGCTACGGAACAAGGCCGCTGCCCCAGTGCCTGCCG
CGAACCCCGGTCCCATAAATTCTAG

Upstream 100 bases:

>100_bases
ACCTCGCGAAGCCAACGCTCCCGTCCCGGTCAACACGGAAATGCCCCTTGAATAAGTTTTTTCAAACGTTTCTTCCGTTC
ACTTTTACCATTTTTTCTCC

Downstream 100 bases:

>100_bases
CCCATTTTCCAGCCCCGCAAGGCGGGGTCCCACCCATGACCCGACTCATCCTGCCCATATGCATCATCAGCCTGCTCAGC
GGCTGCCAGGACGCCAACCC

Product: NADH dehydrogenase (ubiquinone) 30 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 2; NDH-1 subunit C 2 [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MLSLESQIKTAADNAQNRFGKDIITDRYEFRGDITLTVARQAVADVVRWLRDSAGFDMLVNLSSVDNMGESPRFEVNYTL
TQSETGANLSLKTKVDDGEEVPSVTEIFQSANWHEREAWDLMGIKFSGHPDLRRILMWEGYPYFPLRKDFPVQGVPTELP
GVAFTEAAPTQGAPFATEQGRCPSACREPRSHKF

Sequences:

>Translated_194_residues
MLSLESQIKTAADNAQNRFGKDIITDRYEFRGDITLTVARQAVADVVRWLRDSAGFDMLVNLSSVDNMGESPRFEVNYTL
TQSETGANLSLKTKVDDGEEVPSVTEIFQSANWHEREAWDLMGIKFSGHPDLRRILMWEGYPYFPLRKDFPVQGVPTELP
GVAFTEAAPTQGAPFATEQGRCPSACREPRSHKF
>Mature_194_residues
MLSLESQIKTAADNAQNRFGKDIITDRYEFRGDITLTVARQAVADVVRWLRDSAGFDMLVNLSSVDNMGESPRFEVNYTL
TQSETGANLSLKTKVDDGEEVPSVTEIFQSANWHEREAWDLMGIKFSGHPDLRRILMWEGYPYFPLRKDFPVQGVPTELP
GVAFTEAAPTQGAPFATEQGRCPSACREPRSHKF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=125, Percent_Identity=38.4, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI145693162, Length=161, Percent_Identity=34.1614906832298, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32563621, Length=124, Percent_Identity=34.6774193548387, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990788, Length=124, Percent_Identity=34.6774193548387, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24656494, Length=124, Percent_Identity=37.9032258064516, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21805; Mature: 21805

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLESQIKTAADNAQNRFGKDIITDRYEFRGDITLTVARQAVADVVRWLRDSAGFDMLV
CCCCHHHHHHHHHHHHHHHCHHHHHCHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCEEEE
NLSSVDNMGESPRFEVNYTLTQSETGANLSLKTKVDDGEEVPSVTEIFQSANWHEREAWD
ECHHHHCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCHHE
LMGIKFSGHPDLRRILMWEGYPYFPLRKDFPVQGVPTELPGVAFTEAAPTQGAPFATEQG
EEEEEECCCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
RCPSACREPRSHKF
CCCHHHCCCCCCCC
>Mature Secondary Structure
MLSLESQIKTAADNAQNRFGKDIITDRYEFRGDITLTVARQAVADVVRWLRDSAGFDMLV
CCCCHHHHHHHHHHHHHHHCHHHHHCHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCEEEE
NLSSVDNMGESPRFEVNYTLTQSETGANLSLKTKVDDGEEVPSVTEIFQSANWHEREAWD
ECHHHHCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCHHE
LMGIKFSGHPDLRRILMWEGYPYFPLRKDFPVQGVPTELPGVAFTEAAPTQGAPFATEQG
EEEEEECCCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
RCPSACREPRSHKF
CCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA