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The map label for this gene is prpC [H]

Identifier: 187735122

GI number: 187735122

Start: 725315

End: 726094

Strand: Reverse

Name: prpC [H]

Synonym: Amuc_0616

Alternate gene names: 187735122

Gene position: 726094-725315 (Counterclockwise)

Preceding gene: 187735124

Following gene: 187735120

Centisome position: 27.25

GC content: 53.33

Gene sequence:

>780_bases
ATGATGCAGCAGTCTTTTTACCAAGATACTGTTCTGGCTTCCGGATTGTATGGAGACCAGATTCAGGGGGGGCGCGATAA
TCAGCAGGATACCTTTTCCATTCTGGCTGAAGAGGATGCCCTGCTACTGGTTCTGGCGGACGGCATGGGAGGGTACACTG
GCGGAGAACTGGCCAGTCGCGCGGCTGTAGAAGGTTTTTCCCGGGCTTTTGAGCGGGAATCCGTCTCGCCCGGAGAAAAA
ATGAAGGCTGCATTAGCCGCCGCAAATGAACAGGTGCTCGCTGTCCGGAAAAAAGAAGGAAAGGATGAGGAAATGGGAAC
GACGCTGGTAGCGGCCTGGATAGGGAGGGAAGGATTGCGCTGGGTCAGCGTGGGGGATTCCCTCCTGCTTCTTATTAGGA
AAGAAAAAATGTTTCTGCTTAATGAATTGCATCAGTATTCCGAGGAATTGGACCGTATGGCGGATGAAGGAGTCATCAGC
CGGGATGAGGCTTTGAACCATCCTTCCCGGCATTTTTTGACCTCTGCCCTGATGGGGAGGGAAATTTTTTTGGTGAATTT
GCAGGAGGAATGCTTCCCTCTGGTTCCGGGAGACCGTCTTCTGGTTGCCAGTGACGGGGTAGAATCTTATCTGAATTCCA
TGGGGCCGGCACGGATACGGTATTTGTCCATGCTTTCCGCGGAGGAACTGGTGCGTTCCGTGTTGGATGGCATCAGCCGC
GGCGGCGATCCCAACCAGGATAACGCTACACTGATTTGTGTGGAGATACCAGGGGCTTGA

Upstream 100 bases:

>100_bases
CCCTTTGGAAAAAACATCCCAGGACTTCAGGAATGGCTTTTTCCTCCCGCTATTTTTGCTTTATTTAGTCAATCCTGCTG
TGGTATAGTGTTTTATTAGC

Downstream 100 bases:

>100_bases
TCTGCATTAGTGCGGCAAGGAGGTAATTTGCGGACAGGCGATTTTTGAGATTCACATCCTCCGTCTGCCGGACGATGAAT
AAAACCCCGCATGCGTTTCA

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MMQQSFYQDTVLASGLYGDQIQGGRDNQQDTFSILAEEDALLLVLADGMGGYTGGELASRAAVEGFSRAFERESVSPGEK
MKAALAAANEQVLAVRKKEGKDEEMGTTLVAAWIGREGLRWVSVGDSLLLLIRKEKMFLLNELHQYSEELDRMADEGVIS
RDEALNHPSRHFLTSALMGREIFLVNLQEECFPLVPGDRLLVASDGVESYLNSMGPARIRYLSMLSAEELVRSVLDGISR
GGDPNQDNATLICVEIPGA

Sequences:

>Translated_259_residues
MMQQSFYQDTVLASGLYGDQIQGGRDNQQDTFSILAEEDALLLVLADGMGGYTGGELASRAAVEGFSRAFERESVSPGEK
MKAALAAANEQVLAVRKKEGKDEEMGTTLVAAWIGREGLRWVSVGDSLLLLIRKEKMFLLNELHQYSEELDRMADEGVIS
RDEALNHPSRHFLTSALMGREIFLVNLQEECFPLVPGDRLLVASDGVESYLNSMGPARIRYLSMLSAEELVRSVLDGISR
GGDPNQDNATLICVEIPGA
>Mature_259_residues
MMQQSFYQDTVLASGLYGDQIQGGRDNQQDTFSILAEEDALLLVLADGMGGYTGGELASRAAVEGFSRAFERESVSPGEK
MKAALAAANEQVLAVRKKEGKDEEMGTTLVAAWIGREGLRWVSVGDSLLLLIRKEKMFLLNELHQYSEELDRMADEGVIS
RDEALNHPSRHFLTSALMGREIFLVNLQEECFPLVPGDRLLVASDGVESYLNSMGPARIRYLSMLSAEELVRSVLDGISR
GGDPNQDNATLICVEIPGA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 28346; Mature: 28346

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQQSFYQDTVLASGLYGDQIQGGRDNQQDTFSILAEEDALLLVLADGMGGYTGGELASR
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEECCCEEEEEEECCCCCCCCHHHHHH
AAVEGFSRAFERESVSPGEKMKAALAAANEQVLAVRKKEGKDEEMGTTLVAAWIGREGLR
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHCCCCCE
WVSVGDSLLLLIRKEKMFLLNELHQYSEELDRMADEGVISRDEALNHPSRHFLTSALMGR
EEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHCC
EIFLVNLQEECFPLVPGDRLLVASDGVESYLNSMGPARIRYLSMLSAEELVRSVLDGISR
EEEEEEEHHHHCCCCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GGDPNQDNATLICVEIPGA
CCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MMQQSFYQDTVLASGLYGDQIQGGRDNQQDTFSILAEEDALLLVLADGMGGYTGGELASR
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHEEECCCEEEEEEECCCCCCCCHHHHHH
AAVEGFSRAFERESVSPGEKMKAALAAANEQVLAVRKKEGKDEEMGTTLVAAWIGREGLR
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHCCCCCE
WVSVGDSLLLLIRKEKMFLLNELHQYSEELDRMADEGVISRDEALNHPSRHFLTSALMGR
EEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHCC
EIFLVNLQEECFPLVPGDRLLVASDGVESYLNSMGPARIRYLSMLSAEELVRSVLDGISR
EEEEEEEHHHHCCCCCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GGDPNQDNATLICVEIPGA
CCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]