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The map label for this gene is hflX [H]

Identifier: 187735093

GI number: 187735093

Start: 694693

End: 696006

Strand: Reverse

Name: hflX [H]

Synonym: Amuc_0587

Alternate gene names: 187735093

Gene position: 696006-694693 (Counterclockwise)

Preceding gene: 187735094

Following gene: 187735090

Centisome position: 26.13

GC content: 59.06

Gene sequence:

>1314_bases
ATGTTTGAAATCCGCGAAAAACCGGAAATGGTGGAACGGGCCATGCTCGTTTCCGTTTACTTCGATCCCTCCGAGGCTGG
GGAAAAACAGGCCATGCTGGATGAGCTGGAAGACCTTGTCTCCAATCTCGGCATCGGCATCGCAGGGAAGCACCTTATCA
AGTCCAGGGACATGCACGCCAAATTCCTGTGCGGCACCGGAAAGGCGCAGGAAGTGAAACAGCTGGCGCTGGATTGCCGG
GCGGATTGCGTTGTTTTTGACAATATGCTCTCCCCTTCCCAGCAGAGGGAATGGGAACGGCTTGTTGACGAATGCGTCAT
TGACCGTGAAGAGGTCATTCTGGACATCTTTGCCAGGCGCGCCCGGACACGGGAAGCCACCCTGCAGGTGGAACTGGCCC
GCATGCAGTATTCCCTGCCGCGCATGGCCCGCATGTGGAACCACCTGGACCGCCAGGGCGGGGGCTCCGGCGGCGGCAAG
GGAGGCGGCGGAGCCGCCAGGGGGGAAGGGGAAAAGCAGATTGAAGTGGACCGTCGTCTGGCGCGCGCCAGAATTGAGGC
TATTCAAAGGGAACTGGTCCTGGTGACCCGTCAGCGTGCCACGCAGCGCAAGGAACGGGAGCGCCAGGCTGTCGCCACGG
CCGCCATTGTAGGTTATACCAATGCCGGAAAATCCTCCCTCCTGTCCCTGGTGTCCGGGTCTGAAGTCATGGCCAGGGAT
ATGCTTTTTGCCACGCTGGACACCACAACGCGGAAGATAGAGCTTCCCCATGGGCAGCCGCTGCTGCTGACGGATACCGT
GGGCTTCATCCGCAACCTTCCGCACCGTCTGGTGGAAGCGTTCAAGTCCACGCTGGAGGAAGCCGTTCTGGCGGATTTCC
TGATTCAGGTGGTGGACGCTTCCGATCCGGAAGCCGTGCGCCATTATGAAACGACTCTGGAGGTTCTCAATGAACTGGGT
GCGGGTGACAAGCCCATGATCGTAGTTTTAAACAAGGTGGACCTGGTGCCGGAAGAACGGCGCGGGGCCCTGGAAACGCT
GCTGGCGCCTCATTTCAGCGGCAGGGTGGTTCCCATGTCCGTGAAAGAAGGGAATGGTGAGGGAGACCTGCTGAATGCCT
GCGTGGAAATGCTGGAAAGCCGTGTCCGGCGCGCCCGGTTCCTGATTCCCTATACCCGCAGCGACCTGGTGGCCGCCATG
CATAGTGAAGGCAAGGTTTTCTCTACGGAATATGTAGAGGAAGGGACCTTGCTGGAAGCCGTGCTTCCTGTGGCCTTTTA
CAATAAACTGGAGTCATTCCTGGCAGACAGGTAA

Upstream 100 bases:

>100_bases
CTTCCTCTCTTCATGCAGTTGTGATTGTCATAAGCCCGCGGACTTCGCTCTGAAGGATTACCAGCCTACCTCCAGCAAGC
AATTCCGTTAAATTTCCTAT

Downstream 100 bases:

>100_bases
TACCCTGTTCCTGAAGCCTGGGGCTTTGCCTTGCGTTCCGAAGGCCGTTCCGGGGCGGGAAGCGTTTTTTCTTCCGGAGA
CAGTATCCGGATTCCTGGAC

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MFEIREKPEMVERAMLVSVYFDPSEAGEKQAMLDELEDLVSNLGIGIAGKHLIKSRDMHAKFLCGTGKAQEVKQLALDCR
ADCVVFDNMLSPSQQREWERLVDECVIDREEVILDIFARRARTREATLQVELARMQYSLPRMARMWNHLDRQGGGSGGGK
GGGGAARGEGEKQIEVDRRLARARIEAIQRELVLVTRQRATQRKERERQAVATAAIVGYTNAGKSSLLSLVSGSEVMARD
MLFATLDTTTRKIELPHGQPLLLTDTVGFIRNLPHRLVEAFKSTLEEAVLADFLIQVVDASDPEAVRHYETTLEVLNELG
AGDKPMIVVLNKVDLVPEERRGALETLLAPHFSGRVVPMSVKEGNGEGDLLNACVEMLESRVRRARFLIPYTRSDLVAAM
HSEGKVFSTEYVEEGTLLEAVLPVAFYNKLESFLADR

Sequences:

>Translated_437_residues
MFEIREKPEMVERAMLVSVYFDPSEAGEKQAMLDELEDLVSNLGIGIAGKHLIKSRDMHAKFLCGTGKAQEVKQLALDCR
ADCVVFDNMLSPSQQREWERLVDECVIDREEVILDIFARRARTREATLQVELARMQYSLPRMARMWNHLDRQGGGSGGGK
GGGGAARGEGEKQIEVDRRLARARIEAIQRELVLVTRQRATQRKERERQAVATAAIVGYTNAGKSSLLSLVSGSEVMARD
MLFATLDTTTRKIELPHGQPLLLTDTVGFIRNLPHRLVEAFKSTLEEAVLADFLIQVVDASDPEAVRHYETTLEVLNELG
AGDKPMIVVLNKVDLVPEERRGALETLLAPHFSGRVVPMSVKEGNGEGDLLNACVEMLESRVRRARFLIPYTRSDLVAAM
HSEGKVFSTEYVEEGTLLEAVLPVAFYNKLESFLADR
>Mature_437_residues
MFEIREKPEMVERAMLVSVYFDPSEAGEKQAMLDELEDLVSNLGIGIAGKHLIKSRDMHAKFLCGTGKAQEVKQLALDCR
ADCVVFDNMLSPSQQREWERLVDECVIDREEVILDIFARRARTREATLQVELARMQYSLPRMARMWNHLDRQGGGSGGGK
GGGGAARGEGEKQIEVDRRLARARIEAIQRELVLVTRQRATQRKERERQAVATAAIVGYTNAGKSSLLSLVSGSEVMARD
MLFATLDTTTRKIELPHGQPLLLTDTVGFIRNLPHRLVEAFKSTLEEAVLADFLIQVVDASDPEAVRHYETTLEVLNELG
AGDKPMIVVLNKVDLVPEERRGALETLLAPHFSGRVVPMSVKEGNGEGDLLNACVEMLESRVRRARFLIPYTRSDLVAAM
HSEGKVFSTEYVEEGTLLEAVLPVAFYNKLESFLADR

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=231, Percent_Identity=35.4978354978355, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI310124267, Length=231, Percent_Identity=35.4978354978355, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI310124171, Length=231, Percent_Identity=35.4978354978355, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI310124169, Length=231, Percent_Identity=35.4978354978355, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI310133116, Length=231, Percent_Identity=35.0649350649351, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI310133118, Length=231, Percent_Identity=35.0649350649351, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1790615, Length=423, Percent_Identity=39.7163120567376, Blast_Score=251, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17561038, Length=300, Percent_Identity=30.6666666666667, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24650079, Length=314, Percent_Identity=33.7579617834395, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48735; Mature: 48735

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEIREKPEMVERAMLVSVYFDPSEAGEKQAMLDELEDLVSNLGIGIAGKHLIKSRDMHA
CCCCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCE
KFLCGTGKAQEVKQLALDCRADCVVFDNMLSPSQQREWERLVDECVIDREEVILDIFARR
EEEECCCCHHHHHHHHHHCCCCCEEEHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARTREATLQVELARMQYSLPRMARMWNHLDRQGGGSGGGKGGGGAARGEGEKQIEVDRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
ARARIEAIQRELVLVTRQRATQRKERERQAVATAAIVGYTNAGKSSLLSLVSGSEVMARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
MLFATLDTTTRKIELPHGQPLLLTDTVGFIRNLPHRLVEAFKSTLEEAVLADFLIQVVDA
HHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDPEAVRHYETTLEVLNELGAGDKPMIVVLNKVDLVPEERRGALETLLAPHFSGRVVPMS
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEE
VKEGNGEGDLLNACVEMLESRVRRARFLIPYTRSDLVAAMHSEGKVFSTEYVEEGTLLEA
ECCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCEEEHHHHCCCHHHHH
VLPVAFYNKLESFLADR
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEIREKPEMVERAMLVSVYFDPSEAGEKQAMLDELEDLVSNLGIGIAGKHLIKSRDMHA
CCCCCCCHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCE
KFLCGTGKAQEVKQLALDCRADCVVFDNMLSPSQQREWERLVDECVIDREEVILDIFARR
EEEECCCCHHHHHHHHHHCCCCCEEEHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ARTREATLQVELARMQYSLPRMARMWNHLDRQGGGSGGGKGGGGAARGEGEKQIEVDRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
ARARIEAIQRELVLVTRQRATQRKERERQAVATAAIVGYTNAGKSSLLSLVSGSEVMARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
MLFATLDTTTRKIELPHGQPLLLTDTVGFIRNLPHRLVEAFKSTLEEAVLADFLIQVVDA
HHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDPEAVRHYETTLEVLNELGAGDKPMIVVLNKVDLVPEERRGALETLLAPHFSGRVVPMS
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEE
VKEGNGEGDLLNACVEMLESRVRRARFLIPYTRSDLVAAMHSEGKVFSTEYVEEGTLLEA
ECCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCEEEHHHHCCCHHHHH
VLPVAFYNKLESFLADR
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]