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The map label for this gene is atpA [H]

Identifier: 187735015

GI number: 187735015

Start: 597643

End: 599175

Strand: Reverse

Name: atpA [H]

Synonym: Amuc_0508

Alternate gene names: 187735015

Gene position: 599175-597643 (Counterclockwise)

Preceding gene: 187735016

Following gene: 187735014

Centisome position: 22.49

GC content: 57.99

Gene sequence:

>1533_bases
ATGAGCAACATACTTCAAGAACTCGAAGCAGAAATAAAAAAAGCCACGGCTTCCGTCAGTCAGGAAAACGTGGGCGTCAT
TCGTTCCGTGGGGGACGGCGTCGCCAAGATCGAAGGGCTGAGCGGCGTCATGCTCAATGAAATGATAGAGTTCCCCGGCG
GGGTGATGGGGCTGGCGATGAACCTAGAAGAACATGAGGTTGGCGCCGTGATTCTGGGGGATGATTCCAAGTTGAAGGAA
GGGGATCTGGTCAAGTGTTCCGGACGCCTTCTTTCCGTGCCCGTGGGCCGCTCCCTGCTGGGCCGGGTGGTGAACACGCT
GGGAGAACCTATTGACGGCAAAGGGCCGATTGAGGCGGAAGCGTATTACCCGGTGGAAAAAATCGCCTCCGGCATCATCT
CCCGCCAATCCGTTTCCGTGCCCGTCCAGACCGGCATCCTTCCCATTGACGCCATGATTCCCATTGGCCGCGGCCAGCGC
GAACTCATCATCGGGGACCGTGCCACCGGGAAGACCGCCATTGCCATGGATACCATGATTGCCCAGGCGGAACAGAACCG
TCTGGCGGAGGAAGGCAAGCTTCCTGATCACCAGCCTCTCTACAATATTTACGTGGCTATCGGCCAGAAGCGCGCCAACA
TCAGCCGCCTGGTGGCGAAACTGGAGGAAACGGGAGCCATGAAATATTCCATCGTCGTGGCGGCTTCCGCCTCCGATCCT
GCCGCCATGCTGTACCTGGCGCCCTACGCCGGCTGTGCGATGGGGGAATACTTTATGGACAAGGGGGAAGACGCCCTTAT
CGTTTATGACGACCTTTCCAAGCATGCCGTGGCCTACCGCCAGATTTCCCTGATTCTGCGCCGCCCCTCCGGCCGCGAGG
CGTACCCGGGGGACGTATTCTACCTGCACAGCCGCCTGCTGGAACGCGCCGCGCGCATCAACAAGGAACACGGCGGCGGT
TCCCTGACGGCTCTTCCCATTATTGAAACGCAGGCAGGCGACGTTTCCGCCTACATTCCCACGAACGTCATTTCCATCAC
GGACGGCCAGATATTCCTGGAAACGGACCTGTTTTACCAGGGGGTGCGCCCAGCCATCAACGTGGGTATTTCCGTCTCCC
GTGTGGGTTCCTCCGCCCAGACGAAAATTATCAAGAAGCTGGCCGGCTCCATTAAGCTGGATCTGGCCCAATTTACGGAA
TTGCAGGCGTTCGCCCAGTTCGGGTCTGATCTGGACCCCAGCACGAAGGCCAAGCTGGCCCGCGGCCAGCGCATCGTGGA
GCTCTTTAAGCAGAACCAGTATGAGCCCAAATCCCTGGGTCTGGAGGCCGCTGACTTGTATGCCATGCAAAAAGGGTACT
TTGACGACGTTCCGGTGGACAGGATCAAGGAATGCCAGAATGCGTGGGAAGCGGTGATGCAGGATCAGCATCCGGATCTG
CTGGAAAGCATTCTGAAGAAAAAAGACCTGACGCCGGAAATAGACGCAGGGCTTAAAGCCGCTATCGAATCCTTCAAGCT
CAGCTGGAACTAA

Upstream 100 bases:

>100_bases
CAGGTAGGGGACGACGTGAAGGACGGTTCCGTGCGTTCCAGAATCGACCGTCTGGCTGCGATGGCCCGCACCCTTTCCAA
TTAACCAACGAATTTTTCCC

Downstream 100 bases:

>100_bases
CGATTACGGGAGTACTGACACATGGGCAATCTGAGAGACATCAGACGCCGGATCAAGTCCGTCAAAAACACGTCCCAGAT
CACCAGGGCGATGCAGATGG

Product: ATP synthase F1, alpha subunit

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSNILQELEAEIKKATASVSQENVGVIRSVGDGVAKIEGLSGVMLNEMIEFPGGVMGLAMNLEEHEVGAVILGDDSKLKE
GDLVKCSGRLLSVPVGRSLLGRVVNTLGEPIDGKGPIEAEAYYPVEKIASGIISRQSVSVPVQTGILPIDAMIPIGRGQR
ELIIGDRATGKTAIAMDTMIAQAEQNRLAEEGKLPDHQPLYNIYVAIGQKRANISRLVAKLEETGAMKYSIVVAASASDP
AAMLYLAPYAGCAMGEYFMDKGEDALIVYDDLSKHAVAYRQISLILRRPSGREAYPGDVFYLHSRLLERAARINKEHGGG
SLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQGVRPAINVGISVSRVGSSAQTKIIKKLAGSIKLDLAQFTE
LQAFAQFGSDLDPSTKAKLARGQRIVELFKQNQYEPKSLGLEAADLYAMQKGYFDDVPVDRIKECQNAWEAVMQDQHPDL
LESILKKKDLTPEIDAGLKAAIESFKLSWN

Sequences:

>Translated_510_residues
MSNILQELEAEIKKATASVSQENVGVIRSVGDGVAKIEGLSGVMLNEMIEFPGGVMGLAMNLEEHEVGAVILGDDSKLKE
GDLVKCSGRLLSVPVGRSLLGRVVNTLGEPIDGKGPIEAEAYYPVEKIASGIISRQSVSVPVQTGILPIDAMIPIGRGQR
ELIIGDRATGKTAIAMDTMIAQAEQNRLAEEGKLPDHQPLYNIYVAIGQKRANISRLVAKLEETGAMKYSIVVAASASDP
AAMLYLAPYAGCAMGEYFMDKGEDALIVYDDLSKHAVAYRQISLILRRPSGREAYPGDVFYLHSRLLERAARINKEHGGG
SLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQGVRPAINVGISVSRVGSSAQTKIIKKLAGSIKLDLAQFTE
LQAFAQFGSDLDPSTKAKLARGQRIVELFKQNQYEPKSLGLEAADLYAMQKGYFDDVPVDRIKECQNAWEAVMQDQHPDL
LESILKKKDLTPEIDAGLKAAIESFKLSWN
>Mature_509_residues
SNILQELEAEIKKATASVSQENVGVIRSVGDGVAKIEGLSGVMLNEMIEFPGGVMGLAMNLEEHEVGAVILGDDSKLKEG
DLVKCSGRLLSVPVGRSLLGRVVNTLGEPIDGKGPIEAEAYYPVEKIASGIISRQSVSVPVQTGILPIDAMIPIGRGQRE
LIIGDRATGKTAIAMDTMIAQAEQNRLAEEGKLPDHQPLYNIYVAIGQKRANISRLVAKLEETGAMKYSIVVAASASDPA
AMLYLAPYAGCAMGEYFMDKGEDALIVYDDLSKHAVAYRQISLILRRPSGREAYPGDVFYLHSRLLERAARINKEHGGGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQGVRPAINVGISVSRVGSSAQTKIIKKLAGSIKLDLAQFTEL
QAFAQFGSDLDPSTKAKLARGQRIVELFKQNQYEPKSLGLEAADLYAMQKGYFDDVPVDRIKECQNAWEAVMQDQHPDLL
ESILKKKDLTPEIDAGLKAAIESFKLSWN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=505, Percent_Identity=57.6237623762376, Blast_Score=577, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=505, Percent_Identity=57.6237623762376, Blast_Score=577, Evalue=1e-164,
Organism=Homo sapiens, GI19913426, Length=298, Percent_Identity=30.8724832214765, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI19913428, Length=298, Percent_Identity=29.5302013422819, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI32189394, Length=331, Percent_Identity=24.773413897281, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1790172, Length=501, Percent_Identity=58.0838323353293, Blast_Score=564, Evalue=1e-162,
Organism=Escherichia coli, GI1788251, Length=374, Percent_Identity=26.4705882352941, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790170, Length=308, Percent_Identity=24.025974025974, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=508, Percent_Identity=55.9055118110236, Blast_Score=567, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988080, Length=508, Percent_Identity=55.9055118110236, Blast_Score=566, Evalue=1e-162,
Organism=Caenorhabditis elegans, GI71988074, Length=508, Percent_Identity=52.3622047244094, Blast_Score=514, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17510931, Length=345, Percent_Identity=28.1159420289855, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=29.0969899665552, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=334, Percent_Identity=23.0538922155689, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=498, Percent_Identity=56.2248995983936, Blast_Score=568, Evalue=1e-163,
Organism=Saccharomyces cerevisiae, GI6319603, Length=297, Percent_Identity=28.956228956229, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=456, Percent_Identity=24.1228070175439, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=55.2941176470588, Blast_Score=558, Evalue=1e-159,
Organism=Drosophila melanogaster, GI281361666, Length=299, Percent_Identity=30.4347826086957, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24646341, Length=299, Percent_Identity=30.4347826086957, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136796, Length=299, Percent_Identity=30.4347826086957, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24638766, Length=461, Percent_Identity=23.2104121475054, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28574560, Length=439, Percent_Identity=22.3234624145786, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55236; Mature: 55105

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILQELEAEIKKATASVSQENVGVIRSVGDGVAKIEGLSGVMLNEMIEFPGGVMGLAM
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEE
NLEEHEVGAVILGDDSKLKEGDLVKCSGRLLSVPVGRSLLGRVVNTLGEPIDGKGPIEAE
CCCCCCCCEEEECCCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
AYYPVEKIASGIISRQSVSVPVQTGILPIDAMIPIGRGQRELIIGDRATGKTAIAMDTMI
CCCCHHHHHHHHHCCCCCCCCHHCCCEEEHHCCCCCCCCEEEEEECCCCCCCHHHHHHHH
AQAEQNRLAEEGKLPDHQPLYNIYVAIGQKRANISRLVAKLEETGAMKYSIVVAASASDP
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCC
AAMLYLAPYAGCAMGEYFMDKGEDALIVYDDLSKHAVAYRQISLILRRPSGREAYPGDVF
EEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHEECCCCCCCCCCHHH
YLHSRLLERAARINKEHGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEEHHHHH
GVRPAINVGISVSRVGSSAQTKIIKKLAGSIKLDLAQFTELQAFAQFGSDLDPSTKAKLA
CCCHHHHCCEEHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
RGQRIVELFKQNQYEPKSLGLEAADLYAMQKGYFDDVPVDRIKECQNAWEAVMQDQHPDL
HHHHHHHHHHCCCCCHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
LESILKKKDLTPEIDAGLKAAIESFKLSWN
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNILQELEAEIKKATASVSQENVGVIRSVGDGVAKIEGLSGVMLNEMIEFPGGVMGLAM
CHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCEEEEEE
NLEEHEVGAVILGDDSKLKEGDLVKCSGRLLSVPVGRSLLGRVVNTLGEPIDGKGPIEAE
CCCCCCCCEEEECCCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
AYYPVEKIASGIISRQSVSVPVQTGILPIDAMIPIGRGQRELIIGDRATGKTAIAMDTMI
CCCCHHHHHHHHHCCCCCCCCHHCCCEEEHHCCCCCCCCEEEEEECCCCCCCHHHHHHHH
AQAEQNRLAEEGKLPDHQPLYNIYVAIGQKRANISRLVAKLEETGAMKYSIVVAASASDP
HHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCC
AAMLYLAPYAGCAMGEYFMDKGEDALIVYDDLSKHAVAYRQISLILRRPSGREAYPGDVF
EEEEEECCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHEECCCCCCCCCCHHH
YLHSRLLERAARINKEHGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFYQ
HHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCEEEEEEHHHHH
GVRPAINVGISVSRVGSSAQTKIIKKLAGSIKLDLAQFTELQAFAQFGSDLDPSTKAKLA
CCCHHHHCCEEHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
RGQRIVELFKQNQYEPKSLGLEAADLYAMQKGYFDDVPVDRIKECQNAWEAVMQDQHPDL
HHHHHHHHHHCCCCCHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
LESILKKKDLTPEIDAGLKAAIESFKLSWN
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA