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The map label for this gene is gmhB [H]

Identifier: 187734920

GI number: 187734920

Start: 494073

End: 494579

Strand: Reverse

Name: gmhB [H]

Synonym: Amuc_0413

Alternate gene names: 187734920

Gene position: 494579-494073 (Counterclockwise)

Preceding gene: 187734921

Following gene: 187734919

Centisome position: 18.56

GC content: 59.37

Gene sequence:

>507_bases
ATGGCGGGTAAGGCTTTGTTTCTGGACAGGGACGGCGTGGTTAATGTGGATGGCGGGTATGTGCACCGCATAGAGGACTT
CCGGCTGGTTCCCGGAATTCTGAATCTTTGCCGCCAGGCTAAAGAGAAGGGGTATCTGGTGCTGGTGGCGACCAACCAGT
CCGGCATAGGACGCGGCATGTTTTCTGAAGATGACTTTGAGCGGTTGACGGAATATATGAGAGGGGTGTTCCGTTCGTCC
GGTGCGGAGATTGCAGGTGTGTTTCACTGTCCCAGCGCGGATGACGGACATCCCGACCGGAAACCGAATCCCGGCCTGTT
TTTGAAGGCTGCCGCCGCGCATGGGCTGGATATGAAAGCCTGCGTGTCCGTAGGTGACCGGGAGCGGGACATCCGGGCGG
CTCTTGCCGCCGGAGTAGGCCGCAATTTCCTGTTTTCTGCGGAAGATGTCCCCACCCTCGCCACGGCCCGTGTGGAGACG
TTGGAGGAAGTGGCGGCAAGGCTGTGA

Upstream 100 bases:

>100_bases
GAGTTTTGCATTGCCGTTCCTTCCGATGCCACGAACAACATTCAGGAGATGCACATTGCAGTGGGGCATCTGGTTTGCGA
ACTGGTTGAACGGGAGATAT

Downstream 100 bases:

>100_bases
GTTTGGGAATGGCTGTTCAGGATTGGCCTGGCAGCCCTCCCCTTGTTCCGACTGCCGGGTTGGGATGATGAGTGTTCCTG
TGCCAAAACTTTAGAGACAG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MAGKALFLDRDGVVNVDGGYVHRIEDFRLVPGILNLCRQAKEKGYLVLVATNQSGIGRGMFSEDDFERLTEYMRGVFRSS
GAEIAGVFHCPSADDGHPDRKPNPGLFLKAAAAHGLDMKACVSVGDRERDIRAALAAGVGRNFLFSAEDVPTLATARVET
LEEVAARL

Sequences:

>Translated_168_residues
MAGKALFLDRDGVVNVDGGYVHRIEDFRLVPGILNLCRQAKEKGYLVLVATNQSGIGRGMFSEDDFERLTEYMRGVFRSS
GAEIAGVFHCPSADDGHPDRKPNPGLFLKAAAAHGLDMKACVSVGDRERDIRAALAAGVGRNFLFSAEDVPTLATARVET
LEEVAARL
>Mature_167_residues
AGKALFLDRDGVVNVDGGYVHRIEDFRLVPGILNLCRQAKEKGYLVLVATNQSGIGRGMFSEDDFERLTEYMRGVFRSSG
AEIAGVFHCPSADDGHPDRKPNPGLFLKAAAAHGLDMKACVSVGDRERDIRAALAAGVGRNFLFSAEDVPTLATARVETL
EEVAARL

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=148, Percent_Identity=41.8918918918919, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI87082027, Length=143, Percent_Identity=30.0699300699301, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 18151; Mature: 18020

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKALFLDRDGVVNVDGGYVHRIEDFRLVPGILNLCRQAKEKGYLVLVATNQSGIGRGM
CCCCEEEEECCCEEECCCCEEEEECCCEECHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
FSEDDFERLTEYMRGVFRSSGAEIAGVFHCPSADDGHPDRKPNPGLFLKAAAAHGLDMKA
CCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHH
CVSVGDRERDIRAALAAGVGRNFLFSAEDVPTLATARVETLEEVAARL
HHCCCCCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGKALFLDRDGVVNVDGGYVHRIEDFRLVPGILNLCRQAKEKGYLVLVATNQSGIGRGM
CCCEEEEECCCEEECCCCEEEEECCCEECHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
FSEDDFERLTEYMRGVFRSSGAEIAGVFHCPSADDGHPDRKPNPGLFLKAAAAHGLDMKA
CCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHH
CVSVGDRERDIRAALAAGVGRNFLFSAEDVPTLATARVETLEEVAARL
HHCCCCCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11373120; 12101286 [H]