Click here to switch to the map view.

The map label for this gene is lolE [H]

Identifier: 187734695

GI number: 187734695

Start: 229295

End: 230920

Strand: Reverse

Name: lolE [H]

Synonym: Amuc_0182

Alternate gene names: 187734695

Gene position: 230920-229295 (Counterclockwise)

Preceding gene: 187734696

Following gene: 187734694

Centisome position: 8.67

GC content: 56.4

Gene sequence:

>1626_bases
ATGAAGAACCTATTGAGCCGGTACATCAGCCTGAGTCTGGCGCTGCGGTATTTGAACCCGTTGCGGACTTTCTTTTCCAT
TATTACCCTGATTTGCCTGCTGGGCGTATCTCTGGGGGTAATGGTGCTCATTGTCGTGCTGTCCGTCATGGGAGGCCTCC
AGAAGGAAATTCAGGGGAATCTGTTTGCGCACTCCCCGCACGTCCAGGTATGCTACCGGAACGACTTCGGCGTGAGGGAA
GTGATTCCGGACTGGATGGATTTGGGGGAGAAACTCAGGCACGTTCCCGGCGTCCAGTCCACCTACGCCCTGATAGAAGA
CTATGCGCTGGTGGATGTGCAGGGGCGGCAGAGGCCCTGCTTTTTCCGGGCCATTGATACGGAAAACGCCGTCCAGCTGG
AGGATTTGAAGCGTTTGGTGGTAGCTGGCGATGCGGAACTGGACATGGGGGAAAAGGCTGTGGTTTCCTCCATCGTGGCG
GAGAATATGGGATTGAATGTGGGAGATGTTGTCCGGGTTTATACGACCCGCAATTTTCAGGAAATTTCCCACGCCTACCA
GCAGACGGAGCTGCCGATGCTGGCGGAAAAAAACGCGCGGGAACTCAAGGATTTGAAGGAGTGGGGAAAGAACCTGAAGA
CGGAGGGAGAGCGTGAAATGGCCGGCAGAGCCTCCGTGGACAGGGCGTTTTCCCTGCTTAACGGGCTGTTGTCCGTCCCG
CGCAGGGATGCGGAACGTTCCAGCCTGATGGATCTGCTTGCCGTGCTGAACGACGGGGAAATTGCGGACAACGGCAGGGT
GGCCTTTTCGCAAGGAACGCGGAAGGAATGGGAAACCGTTTTGAATGGTTTCAAGGCCGGGGCAAAAAATGAGGCGGATA
TGGAATGCTTCCGGAAAATCAAGGAGCTGGTGATGCCGAAAGACCTGGAGGTGATCGGAATTTACCGGGCCTCCCAGCAT
ACGCCCAGCCCGGATCTTTTCATTCCGCTGGTCATCGGTCAGGAATTGCTGGGTTATGAGGATGACGTGGTGCAGGCCGT
GGCCCTGCGCGTGGAAGACCCTTACCATGTGGAAACGATGCTGGCCCCCGTGATGCAGGCGCTGGAAAAGGAGAAGCCTT
CTTCCGCATGGACGCTGGAAACCTGGCATGACCGCTTTAACGCGTGGTTTGAATTGATGCAGAAGGAGCGCATGATGATG
AGCTTTGTCCTGTCCTTCATCTCCCTGATTTCCGCTTTTTGCATCATGGCGGTGATGTTTACCGTTTCCATCCAGAGGAA
AAAGGAAATCGCCGTGATGAAGGCTTTGGGAGCCACGCCGTTCCAGGTGGTGCGCGTTTTTCTGTGGCAGGGCGTCATCA
TCGGTTTTGTGGGAGCTCTCCTGGGTGTAGGGCTGGGGCTTCTGGTGCTGGAATACCGCATGCAGATTCAGGGTTTTCTT
GCGGGAATAGGCTTTGACCCGTTCCCTGTGGCCTTCCACGGCACGGCGAATATCCCGGTGGTGATTGACTGGGCGGAGCT
GGCATGGCAGGCGGTGAAAGCTTTTGTCATGGTCGTGGTGGCATCCATCATTCCTGCCCTGATCACGGCGCGCCAGGATC
CGGCCCGCTCCCTGCGCAGTATGTAA

Upstream 100 bases:

>100_bases
AATGGCTGGGTGCCGGAGGCAGGTAAACGATCTCCTTCCCCGGAACATGTTTTAGGCTTGGAAAGGGGAGCGGGATCAGG
CAAGGTGTGCCGCGTTATTC

Downstream 100 bases:

>100_bases
CAGGAATCGCCTATGGATATTTACTGGATTCAGGATCATGAACGGAAGGGGCCTCTGCCGGAAGTGGAGGTCATTTCCAT
GCTGGAGGCGGGCCTCATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKNLLSRYISLSLALRYLNPLRTFFSIITLICLLGVSLGVMVLIVVLSVMGGLQKEIQGNLFAHSPHVQVCYRNDFGVRE
VIPDWMDLGEKLRHVPGVQSTYALIEDYALVDVQGRQRPCFFRAIDTENAVQLEDLKRLVVAGDAELDMGEKAVVSSIVA
ENMGLNVGDVVRVYTTRNFQEISHAYQQTELPMLAEKNARELKDLKEWGKNLKTEGEREMAGRASVDRAFSLLNGLLSVP
RRDAERSSLMDLLAVLNDGEIADNGRVAFSQGTRKEWETVLNGFKAGAKNEADMECFRKIKELVMPKDLEVIGIYRASQH
TPSPDLFIPLVIGQELLGYEDDVVQAVALRVEDPYHVETMLAPVMQALEKEKPSSAWTLETWHDRFNAWFELMQKERMMM
SFVLSFISLISAFCIMAVMFTVSIQRKKEIAVMKALGATPFQVVRVFLWQGVIIGFVGALLGVGLGLLVLEYRMQIQGFL
AGIGFDPFPVAFHGTANIPVVIDWAELAWQAVKAFVMVVVASIIPALITARQDPARSLRSM

Sequences:

>Translated_541_residues
MKNLLSRYISLSLALRYLNPLRTFFSIITLICLLGVSLGVMVLIVVLSVMGGLQKEIQGNLFAHSPHVQVCYRNDFGVRE
VIPDWMDLGEKLRHVPGVQSTYALIEDYALVDVQGRQRPCFFRAIDTENAVQLEDLKRLVVAGDAELDMGEKAVVSSIVA
ENMGLNVGDVVRVYTTRNFQEISHAYQQTELPMLAEKNARELKDLKEWGKNLKTEGEREMAGRASVDRAFSLLNGLLSVP
RRDAERSSLMDLLAVLNDGEIADNGRVAFSQGTRKEWETVLNGFKAGAKNEADMECFRKIKELVMPKDLEVIGIYRASQH
TPSPDLFIPLVIGQELLGYEDDVVQAVALRVEDPYHVETMLAPVMQALEKEKPSSAWTLETWHDRFNAWFELMQKERMMM
SFVLSFISLISAFCIMAVMFTVSIQRKKEIAVMKALGATPFQVVRVFLWQGVIIGFVGALLGVGLGLLVLEYRMQIQGFL
AGIGFDPFPVAFHGTANIPVVIDWAELAWQAVKAFVMVVVASIIPALITARQDPARSLRSM
>Mature_541_residues
MKNLLSRYISLSLALRYLNPLRTFFSIITLICLLGVSLGVMVLIVVLSVMGGLQKEIQGNLFAHSPHVQVCYRNDFGVRE
VIPDWMDLGEKLRHVPGVQSTYALIEDYALVDVQGRQRPCFFRAIDTENAVQLEDLKRLVVAGDAELDMGEKAVVSSIVA
ENMGLNVGDVVRVYTTRNFQEISHAYQQTELPMLAEKNARELKDLKEWGKNLKTEGEREMAGRASVDRAFSLLNGLLSVP
RRDAERSSLMDLLAVLNDGEIADNGRVAFSQGTRKEWETVLNGFKAGAKNEADMECFRKIKELVMPKDLEVIGIYRASQH
TPSPDLFIPLVIGQELLGYEDDVVQAVALRVEDPYHVETMLAPVMQALEKEKPSSAWTLETWHDRFNAWFELMQKERMMM
SFVLSFISLISAFCIMAVMFTVSIQRKKEIAVMKALGATPFQVVRVFLWQGVIIGFVGALLGVGLGLLVLEYRMQIQGFL
AGIGFDPFPVAFHGTANIPVVIDWAELAWQAVKAFVMVVVASIIPALITARQDPARSLRSM

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=230, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 60519; Mature: 60519

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLLSRYISLSLALRYLNPLRTFFSIITLICLLGVSLGVMVLIVVLSVMGGLQKEIQGN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
LFAHSPHVQVCYRNDFGVREVIPDWMDLGEKLRHVPGVQSTYALIEDYALVDVQGRQRPC
EEECCCCEEEEECCCCCHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCCC
FFRAIDTENAVQLEDLKRLVVAGDAELDMGEKAVVSSIVAENMGLNVGDVVRVYTTRNFQ
EEEEECCCCCEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEHHCCCHH
EISHAYQQTELPMLAEKNARELKDLKEWGKNLKTEGEREMAGRASVDRAFSLLNGLLSVP
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
RRDAERSSLMDLLAVLNDGEIADNGRVAFSQGTRKEWETVLNGFKAGAKNEADMECFRKI
CCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
KELVMPKDLEVIGIYRASQHTPSPDLFIPLVIGQELLGYEDDVVQAVALRVEDPYHVETM
HHHHCCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHH
LAPVMQALEKEKPSSAWTLETWHDRFNAWFELMQKERMMMSFVLSFISLISAFCIMAVMF
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSIQRKKEIAVMKALGATPFQVVRVFLWQGVIIGFVGALLGVGLGLLVLEYRMQIQGFL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIGFDPFPVAFHGTANIPVVIDWAELAWQAVKAFVMVVVASIIPALITARQDPARSLRS
HHCCCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
M
C
>Mature Secondary Structure
MKNLLSRYISLSLALRYLNPLRTFFSIITLICLLGVSLGVMVLIVVLSVMGGLQKEIQGN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
LFAHSPHVQVCYRNDFGVREVIPDWMDLGEKLRHVPGVQSTYALIEDYALVDVQGRQRPC
EEECCCCEEEEECCCCCHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCCC
FFRAIDTENAVQLEDLKRLVVAGDAELDMGEKAVVSSIVAENMGLNVGDVVRVYTTRNFQ
EEEEECCCCCEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHEEEHHCCCHH
EISHAYQQTELPMLAEKNARELKDLKEWGKNLKTEGEREMAGRASVDRAFSLLNGLLSVP
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
RRDAERSSLMDLLAVLNDGEIADNGRVAFSQGTRKEWETVLNGFKAGAKNEADMECFRKI
CCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
KELVMPKDLEVIGIYRASQHTPSPDLFIPLVIGQELLGYEDDVVQAVALRVEDPYHVETM
HHHHCCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHH
LAPVMQALEKEKPSSAWTLETWHDRFNAWFELMQKERMMMSFVLSFISLISAFCIMAVMF
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVSIQRKKEIAVMKALGATPFQVVRVFLWQGVIIGFVGALLGVGLGLLVLEYRMQIQGFL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGIGFDPFPVAFHGTANIPVVIDWAELAWQAVKAFVMVVVASIIPALITARQDPARSLRS
HHCCCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
M
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]