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The map label for this gene is 187734659

Identifier: 187734659

GI number: 187734659

Start: 178409

End: 180544

Strand: Direct

Name: 187734659

Synonym: Amuc_0146

Alternate gene names: NA

Gene position: 178409-180544 (Clockwise)

Preceding gene: 187734654

Following gene: 187734661

Centisome position: 6.7

GC content: 51.64

Gene sequence:

>2136_bases
ATGTTTAAATTCAAACACCGGACATCCTGTATCTTGACCGTACTCGCGGGGATAATCTCCATTCAGGTAGGGAATGCCAT
CACCGTCCCGTGGCTCAGACCTTATATTAACGGTGAAGAAGTGGTCGGAACTACGCTGGAAAGCCGTTACAGCACACCTG
ACGGAGAATCCGCCAATCCTGTGATCTGGTGGGAAAAAGCAGATGTCCGAAACGGAAAAACCGTAGTGGTTCAGCAGAGC
CGTGATGCGGAATCCTACACCCTGACGGACAAGGATGCAGGAAAATATTTCCGGATTATTGTAGGCTGCGGAACCAAAGA
CGAAGCTGCCAGCCAGTGGATCGGCCCGGTCATCACGGAAAAACAGGCGGAAAGCATCAATAACCGTTTCCATCCCGGCA
GGAGCTACCAGGAAAATGTGAACGAACTTCAAAAGGAACTATCTGAAAAACTTCGAAACGCCGTGTACTTTACCGTAGAT
ACGGACAAGCTGCATGGCGCACCCTGCGTGATGGCCAGAAATAAACGAATCCCTCTGCCCGAAGATATCAGACCTTTCCG
GGAAAACGGAAAAATCTATATCAGCCAACCCTTTGTACAGGCCATTTTCAACAGGGAACTGCCTGATGAAATCATGGAGG
AAGCAGCCGGACAGAAAGCTTATGAAATAAGCAATGTGGCCAGGGTTCTGCAACTCAACCTCTGGCAGGGAGACAAGGAA
AAATCTCCCGTACCGAACTTTCGCATGCAACCCATGGCGGAAGGACTGGTGATTCTCTCTCCTGAAAAAGACATCTTCTC
TCCAGTAGAAGACCGTGACCTGATTAATGAAGCCGTCAACGGGCTCTTCGATTTCAAGGCCGATAATAAACAGTTAAAAT
GGTTTCGGGATGCCAAATTCGGCTTGTTTGTTCACTGGAACCCTTCTTCCCTGCTGGAACGGGAAATAAGCTGGGAACGC
AATGCGGCGCGTCCCAAAGACAGCGCGAGCGGTCATAAGAATACCGTAGACTTTGAGTACGACTCCGCCCACCGCCGCTT
CAACCCCAAGCAATATGACCCCAGAAAATGGATGTCCGTCGCCAAAAAAAGCGGTATGAAATACGCCGTGCTGACCACCA
AGCATCACGACGGCTTCTCTAACTTCCCCTCCAACTACGACACCTTCACCATTGCTGCCACCCCCTACGGCAAAGACATC
GTGGAACAATTCGCGGCGGCAGTTCATGCGGCCGGGCTCAGACTGGGATTTTATTATTCTGGAAGAGACTGGTACAACCC
CTACTACCTGACCGACCAGCACTACCGTTATCTGGAATACTACTTCGGCCAAGTCAGCGAACTGCTCACCCGCTACGGCC
AAGTGGATGTGCTCTGGTTCGACAGCCTGGGCAATAGCTCCCTCAACCAGTGGGATCCCCGCACCATGATACGCCGCATC
AAGCAGTACCAGCCGGACATTCTGATCAACAACCGCATGAACAGCACCCGCGGAGGCAATAAGGAACCGCTGCCCGATGA
TTTGAAAGGGGATTTCCTGACGCCGGAATGCAAGCTAGGCCCCTTCAACACTCAAACGCCTTGGGAAAGCTGCATGACCG
TGGCGGATATCCCCGGCACCCGCTGGACGGGCAACTGGTCCTACACATCCAACGCAACAACCAAACCCGTCGAAACCTCC
GTCAAATTCCTGATCAATAACATTGTCAAGGACGGCAACCTGCTTTACAACATCGGTCCCACTCCACTGGGAACATTTGA
TCCGAAACAGGCTGAAACTTTTCTGTCCATGGGAAAATGGATTGCTCTCTACAAGGAGGCCATTTACAACACTCGCGGAG
GCCCCTACAGGGACCAGCCATGGGGCGGCAGTTGCTACAGAGCGGATCACAACGGCAAAAAAACCGTTTACCTGCACGTC
AGCCCGCTGATTGCCCGACAGGGAAAAGAGCTGAAGGGAAATACCCCCCTGTTCATCAAAGATATCGGGGAAAAATTCAC
GAGAGCGACCCTCATTGTGAACGGTACCGGAAACGGAAAATTCGTCAGGCTTGAAAAGGAAGGAGACCAGTACAAAATCA
CTTTGCCCGAGGGTGTCACCTGGGACAGGCTGGATACCGTCATCAAACTTCAATAA

Upstream 100 bases:

>100_bases
ATTTCATAGAAAGAAAAACACCCCTCTTCCTTACTGGTCTTTTACAAAACGGAGGGGGTTTATCCTGTTCTCCCGGTTAT
TCCTCCTCTAAATTTTTCCC

Downstream 100 bases:

>100_bases
CCCGTTCTTCCAAGAAAACAGCATGCCTTTCCCGCACTCTCTCCTAGACCGGATTTTTATTACCGGAGAATAGTGTTGCC
GCCACACGGTACTCTTGCCT

Product: Alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Calx-Beta Domain-Containing Protein; Alpha-L-Fucosidase Protein; Exported Alpha-L-Fucosidase Protein; Alpha-1 3/4-Fucosidase; Lipoprotein; Exporte Hydrolase; Exported Fucosidase; Alpha-L-Fucosidase Family Protein; Alpha-L-Fucosidase-Like Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Twin-Arginine Translocation Pathway Signal; Ig Domain-Containing; Alpha-L-Fucosidase Superfamily; Fucosidase; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; Coagulation Factor 5/8 Type Domain-Containing Protein; DS Domain-Containing Protein; Glycoside Hydrolase

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MFKFKHRTSCILTVLAGIISIQVGNAITVPWLRPYINGEEVVGTTLESRYSTPDGESANPVIWWEKADVRNGKTVVVQQS
RDAESYTLTDKDAGKYFRIIVGCGTKDEAASQWIGPVITEKQAESINNRFHPGRSYQENVNELQKELSEKLRNAVYFTVD
TDKLHGAPCVMARNKRIPLPEDIRPFRENGKIYISQPFVQAIFNRELPDEIMEEAAGQKAYEISNVARVLQLNLWQGDKE
KSPVPNFRMQPMAEGLVILSPEKDIFSPVEDRDLINEAVNGLFDFKADNKQLKWFRDAKFGLFVHWNPSSLLEREISWER
NAARPKDSASGHKNTVDFEYDSAHRRFNPKQYDPRKWMSVAKKSGMKYAVLTTKHHDGFSNFPSNYDTFTIAATPYGKDI
VEQFAAAVHAAGLRLGFYYSGRDWYNPYYLTDQHYRYLEYYFGQVSELLTRYGQVDVLWFDSLGNSSLNQWDPRTMIRRI
KQYQPDILINNRMNSTRGGNKEPLPDDLKGDFLTPECKLGPFNTQTPWESCMTVADIPGTRWTGNWSYTSNATTKPVETS
VKFLINNIVKDGNLLYNIGPTPLGTFDPKQAETFLSMGKWIALYKEAIYNTRGGPYRDQPWGGSCYRADHNGKKTVYLHV
SPLIARQGKELKGNTPLFIKDIGEKFTRATLIVNGTGNGKFVRLEKEGDQYKITLPEGVTWDRLDTVIKLQ

Sequences:

>Translated_711_residues
MFKFKHRTSCILTVLAGIISIQVGNAITVPWLRPYINGEEVVGTTLESRYSTPDGESANPVIWWEKADVRNGKTVVVQQS
RDAESYTLTDKDAGKYFRIIVGCGTKDEAASQWIGPVITEKQAESINNRFHPGRSYQENVNELQKELSEKLRNAVYFTVD
TDKLHGAPCVMARNKRIPLPEDIRPFRENGKIYISQPFVQAIFNRELPDEIMEEAAGQKAYEISNVARVLQLNLWQGDKE
KSPVPNFRMQPMAEGLVILSPEKDIFSPVEDRDLINEAVNGLFDFKADNKQLKWFRDAKFGLFVHWNPSSLLEREISWER
NAARPKDSASGHKNTVDFEYDSAHRRFNPKQYDPRKWMSVAKKSGMKYAVLTTKHHDGFSNFPSNYDTFTIAATPYGKDI
VEQFAAAVHAAGLRLGFYYSGRDWYNPYYLTDQHYRYLEYYFGQVSELLTRYGQVDVLWFDSLGNSSLNQWDPRTMIRRI
KQYQPDILINNRMNSTRGGNKEPLPDDLKGDFLTPECKLGPFNTQTPWESCMTVADIPGTRWTGNWSYTSNATTKPVETS
VKFLINNIVKDGNLLYNIGPTPLGTFDPKQAETFLSMGKWIALYKEAIYNTRGGPYRDQPWGGSCYRADHNGKKTVYLHV
SPLIARQGKELKGNTPLFIKDIGEKFTRATLIVNGTGNGKFVRLEKEGDQYKITLPEGVTWDRLDTVIKLQ
>Mature_711_residues
MFKFKHRTSCILTVLAGIISIQVGNAITVPWLRPYINGEEVVGTTLESRYSTPDGESANPVIWWEKADVRNGKTVVVQQS
RDAESYTLTDKDAGKYFRIIVGCGTKDEAASQWIGPVITEKQAESINNRFHPGRSYQENVNELQKELSEKLRNAVYFTVD
TDKLHGAPCVMARNKRIPLPEDIRPFRENGKIYISQPFVQAIFNRELPDEIMEEAAGQKAYEISNVARVLQLNLWQGDKE
KSPVPNFRMQPMAEGLVILSPEKDIFSPVEDRDLINEAVNGLFDFKADNKQLKWFRDAKFGLFVHWNPSSLLEREISWER
NAARPKDSASGHKNTVDFEYDSAHRRFNPKQYDPRKWMSVAKKSGMKYAVLTTKHHDGFSNFPSNYDTFTIAATPYGKDI
VEQFAAAVHAAGLRLGFYYSGRDWYNPYYLTDQHYRYLEYYFGQVSELLTRYGQVDVLWFDSLGNSSLNQWDPRTMIRRI
KQYQPDILINNRMNSTRGGNKEPLPDDLKGDFLTPECKLGPFNTQTPWESCMTVADIPGTRWTGNWSYTSNATTKPVETS
VKFLINNIVKDGNLLYNIGPTPLGTFDPKQAETFLSMGKWIALYKEAIYNTRGGPYRDQPWGGSCYRADHNGKKTVYLHV
SPLIARQGKELKGNTPLFIKDIGEKFTRATLIVNGTGNGKFVRLEKEGDQYKITLPEGVTWDRLDTVIKLQ

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40068512, Length=349, Percent_Identity=29.2263610315186, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI119360348, Length=347, Percent_Identity=25.9365994236311, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71997700, Length=353, Percent_Identity=24.3626062322946, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24662717, Length=371, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=5e-28,
Organism=Drosophila melanogaster, GI78706642, Length=371, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 81212; Mature: 81212

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFKHRTSCILTVLAGIISIQVGNAITVPWLRPYINGEEVVGTTLESRYSTPDGESANP
CCCCCCHHHHHHHHHHHHHEEECCCEEECCCCCCCCCCCHHCCHHHHHCCCCCCCCCCCC
VIWWEKADVRNGKTVVVQQSRDAESYTLTDKDAGKYFRIIVGCGTKDEAASQWIGPVITE
EEEEECCCCCCCCEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHCCHHHH
KQAESINNRFHPGRSYQENVNELQKELSEKLRNAVYFTVDTDKLHGAPCVMARNKRIPLP
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECCCCCCCC
EDIRPFRENGKIYISQPFVQAIFNRELPDEIMEEAAGQKAYEISNVARVLQLNLWQGDKE
HHHHHHHHCCEEEEECHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCC
KSPVPNFRMQPMAEGLVILSPEKDIFSPVEDRDLINEAVNGLFDFKADNKQLKWFRDAKF
CCCCCCCCCCCCCCCEEEECCCHHHHCCCHHHHHHHHHHHHEEECCCCCCCEEEEECCCE
GLFVHWNPSSLLEREISWERNAARPKDSASGHKNTVDFEYDSAHRRFNPKQYDPRKWMSV
EEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCHHHHHHH
AKKSGMKYAVLTTKHHDGFSNFPSNYDTFTIAATPYGKDIVEQFAAAVHAAGLRLGFYYS
HHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEEEEC
GRDWYNPYYLTDQHYRYLEYYFGQVSELLTRYGQVDVLWFDSLGNSSLNQWDPRTMIRRI
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
KQYQPDILINNRMNSTRGGNKEPLPDDLKGDFLTPECKLGPFNTQTPWESCMTVADIPGT
HHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEECCCCC
RWTGNWSYTSNATTKPVETSVKFLINNIVKDGNLLYNIGPTPLGTFDPKQAETFLSMGKW
EECCCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
IALYKEAIYNTRGGPYRDQPWGGSCYRADHNGKKTVYLHVSPLIARQGKELKGNTPLFIK
HHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECHHHHHCCCCCCCCCCEEHH
DIGEKFTRATLIVNGTGNGKFVRLEKEGDQYKITLPEGVTWDRLDTVIKLQ
HHHHHHEEEEEEEEECCCCEEEEEECCCCEEEEECCCCCCHHHHCEEEEEC
>Mature Secondary Structure
MFKFKHRTSCILTVLAGIISIQVGNAITVPWLRPYINGEEVVGTTLESRYSTPDGESANP
CCCCCCHHHHHHHHHHHHHEEECCCEEECCCCCCCCCCCHHCCHHHHHCCCCCCCCCCCC
VIWWEKADVRNGKTVVVQQSRDAESYTLTDKDAGKYFRIIVGCGTKDEAASQWIGPVITE
EEEEECCCCCCCCEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHCCHHHH
KQAESINNRFHPGRSYQENVNELQKELSEKLRNAVYFTVDTDKLHGAPCVMARNKRIPLP
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEECCCCCCCC
EDIRPFRENGKIYISQPFVQAIFNRELPDEIMEEAAGQKAYEISNVARVLQLNLWQGDKE
HHHHHHHHCCEEEEECHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCC
KSPVPNFRMQPMAEGLVILSPEKDIFSPVEDRDLINEAVNGLFDFKADNKQLKWFRDAKF
CCCCCCCCCCCCCCCEEEECCCHHHHCCCHHHHHHHHHHHHEEECCCCCCCEEEEECCCE
GLFVHWNPSSLLEREISWERNAARPKDSASGHKNTVDFEYDSAHRRFNPKQYDPRKWMSV
EEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCHHHHHHH
AKKSGMKYAVLTTKHHDGFSNFPSNYDTFTIAATPYGKDIVEQFAAAVHAAGLRLGFYYS
HHHCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEEEEC
GRDWYNPYYLTDQHYRYLEYYFGQVSELLTRYGQVDVLWFDSLGNSSLNQWDPRTMIRRI
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
KQYQPDILINNRMNSTRGGNKEPLPDDLKGDFLTPECKLGPFNTQTPWESCMTVADIPGT
HHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEECCCCC
RWTGNWSYTSNATTKPVETSVKFLINNIVKDGNLLYNIGPTPLGTFDPKQAETFLSMGKW
EECCCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
IALYKEAIYNTRGGPYRDQPWGGSCYRADHNGKKTVYLHVSPLIARQGKELKGNTPLFIK
HHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECHHHHHCCCCCCCCCCEEHH
DIGEKFTRATLIVNGTGNGKFVRLEKEGDQYKITLPEGVTWDRLDTVIKLQ
HHHHHHEEEEEEEEECCCCEEEEEECCCCEEEEECCCCCCHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA