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The map label for this gene is pyrR

Identifier: 187734627

GI number: 187734627

Start: 141269

End: 141802

Strand: Reverse

Name: pyrR

Synonym: Amuc_0113

Alternate gene names: 187734627

Gene position: 141802-141269 (Counterclockwise)

Preceding gene: 187734628

Following gene: 187734626

Centisome position: 5.32

GC content: 59.93

Gene sequence:

>534_bases
ATGACTCCTCCTTCACAGGAAATCGTATTGGACGGTCCGGGAATTTCCCGTGCGCTTGAGCGCATGGCCCACGGCATTGT
GGCCCGTTTCCCCGGAGAACCTCTCGCCATCGTCGGCCTGCTCAGCCAGGGGGATGTGATTGCCCGGCGTCTGGTGGACA
AGGTAAAGGAGCTGGGAGTGGAAGCCCAGTACGGCTCTATTGATATTTCCCTGTACCGGGATGACATCTTCAAGCTGGAA
GCCCGGCCTTCCCTCCGTTCCTCCAATTTGCCGTTTTCCACGGATGACATGAGGGTCGTGCTGGTGGACGACGTCCTTTA
TACGGGGCGCACCATACGTGCAGCCCTGAACGCCCTTTTCGACTACGGCCGTCCAGCCCGTATTGAACTGGCGTGCCTGA
TTGACCGCGGCGGGCGGGAAGTTCCCATCCAGCCGGATTATACGGGGCACGTGCTGGACCATGCCGGAGCCAAGGTCATC
GTAAGCATGAAGGAGGCTGACGGCGAGGACAGCGTGGTCATTCCCTCCCACTGA

Upstream 100 bases:

>100_bases
TTGGCTTGCATAAGAAAACCCCCGTCAATGCCGCCATGGCCGCCCACCGCATTTTAAAACTGGCGGGGCTGTAACGTGAA
CTTTTTCCCCCATCCGGCAA

Downstream 100 bases:

>100_bases
AAATTTCCCAATCCATTCTCCGTTTCCCATGAATCATCCCCGCAAGGATCTTCTTAATATCTCCTCATTGACTGACGAGG
AAATTCACACGCTGCTGGAT

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MTPPSQEIVLDGPGISRALERMAHGIVARFPGEPLAIVGLLSQGDVIARRLVDKVKELGVEAQYGSIDISLYRDDIFKLE
ARPSLRSSNLPFSTDDMRVVLVDDVLYTGRTIRAALNALFDYGRPARIELACLIDRGGREVPIQPDYTGHVLDHAGAKVI
VSMKEADGEDSVVIPSH

Sequences:

>Translated_177_residues
MTPPSQEIVLDGPGISRALERMAHGIVARFPGEPLAIVGLLSQGDVIARRLVDKVKELGVEAQYGSIDISLYRDDIFKLE
ARPSLRSSNLPFSTDDMRVVLVDDVLYTGRTIRAALNALFDYGRPARIELACLIDRGGREVPIQPDYTGHVLDHAGAKVI
VSMKEADGEDSVVIPSH
>Mature_176_residues
TPPSQEIVLDGPGISRALERMAHGIVARFPGEPLAIVGLLSQGDVIARRLVDKVKELGVEAQYGSIDISLYRDDIFKLEA
RPSLRSSNLPFSTDDMRVVLVDDVLYTGRTIRAALNALFDYGRPARIELACLIDRGGREVPIQPDYTGHVLDHAGAKVIV
SMKEADGEDSVVIPSH

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_AKKM8 (B2ULR4)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001876739.1
- ProteinModelPortal:   B2ULR4
- SMR:   B2ULR4
- GeneID:   6274930
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_0113
- HOGENOM:   HBG641958
- OMA:   ELDITFF
- GO:   GO:0006350
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19303; Mature: 19172

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPSQEIVLDGPGISRALERMAHGIVARFPGEPLAIVGLLSQGDVIARRLVDKVKELGV
CCCCCCEEEEECCCHHHHHHHHHHHHEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
EAQYGSIDISLYRDDIFKLEARPSLRSSNLPFSTDDMRVVLVDDVLYTGRTIRAALNALF
CCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHH
DYGRPARIELACLIDRGGREVPIQPDYTGHVLDHAGAKVIVSMKEADGEDSVVIPSH
HCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCCEEECCC
>Mature Secondary Structure 
TPPSQEIVLDGPGISRALERMAHGIVARFPGEPLAIVGLLSQGDVIARRLVDKVKELGV
CCCCCEEEEECCCHHHHHHHHHHHHEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
EAQYGSIDISLYRDDIFKLEARPSLRSSNLPFSTDDMRVVLVDDVLYTGRTIRAALNALF
CCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHH
DYGRPARIELACLIDRGGREVPIQPDYTGHVLDHAGAKVIVSMKEADGEDSVVIPSH
HCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA