Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 187734584

GI number: 187734584

Start: 92893

End: 93858

Strand: Direct

Name: trpS [H]

Synonym: Amuc_0070

Alternate gene names: 187734584

Gene position: 92893-93858 (Clockwise)

Preceding gene: 187734583

Following gene: 187734585

Centisome position: 3.49

GC content: 57.76

Gene sequence:

>966_bases
ATGCGTATCATCACAGGTCTTCAACCCAGCGGCAAGCTGCATGTCGGCAACTACTTCGGAGCCATGGAACCGGCTGTCCG
CATGCAGGAAAGCGGGGAATCTTTCTACTTCCTGGCGGACTACCACGCCATGAGCACCGTTCACGACGCGAACGCGCTGA
GGGAAAACTGCAGCAACCTCGCTACGGACTTTCTGGCCGTGGGCCTGGATCCCGAAAAATGCGTCTTTTTCCGCCAGTCC
GCCGTGCCGGAAGTCAATGAACTGGCCTGGATACTCAGCACCGTCTGTCCGATGGGCCTGCTGGAACGCTGCCATTCCTA
CAAAGATAAAATCGCCAAGGGATTCTCCCCCAGCAACGCCCTGTTCACCTACCCCGTGCTGATGGCTGCCGACATCCTGA
TGTATGACTCCGACCTGGTGCCCGTAGGCAAGGACCAGAAACAGCATCTGGAAGTCACACGCGACCTGGCGGGCAAAATG
AACGAACAATTCGGAGAAGGCACCTGCAAACTTCCGGATGCGCTCATTGCGGAAAGCACAGCCATTGTTCCGGGGCTGGA
CGGGCAGAAAATGAGTAAAAGCTATAATAACACGCTCCCTATTTTCGGAGAGGAAAAAGCTGTCCGCAAACTCATCATGA
GAATCCCCACGGATTCCACCCCCGTGGAAGATCCCAAACCGACGGAAGGTTCCGTCATCCTGCAGCTTTACAAACTCTTT
GCCTCCGCGCAGGGTTATGAAGACATGGTGCGCGGTTTCCAGAACGGGGGATGCGGCTATGGAGACTTCAAAAAGCGCCT
CTTTGACGCTTACTGGGAATACTTCCGGCCCGCGCGCGAACGCAGGGCGGAACTGGAAGCCAATCAGGACTATGTGCGCC
GGACGCTGGAAGAAGGCGCCCGCAAGGCGCGCGAGACGGCCTCTGTAGTGCTGGACAGGGTGCGCCGCGCCGTGGGGCTG
GCCTGA

Upstream 100 bases:

>100_bases
CAGGCACATGCCGGAAAAAAATCCAGCCGGCGGCCCCGCCTGTCTTTGACTCTCCCCTTTCTTGACTTGCCGGGCGCGAA
CAGGCAAAATCCCGCGCGCA

Downstream 100 bases:

>100_bases
AACGGAATAAAACGGAACACCCGGGAAAGCCGGGGCAGCACACGTTTTTTTGTGGCATGGAAAAGTACGGAATGTTATAC
AGAAAGATATGAAGAATATT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRIITGLQPSGKLHVGNYFGAMEPAVRMQESGESFYFLADYHAMSTVHDANALRENCSNLATDFLAVGLDPEKCVFFRQS
AVPEVNELAWILSTVCPMGLLERCHSYKDKIAKGFSPSNALFTYPVLMAADILMYDSDLVPVGKDQKQHLEVTRDLAGKM
NEQFGEGTCKLPDALIAESTAIVPGLDGQKMSKSYNNTLPIFGEEKAVRKLIMRIPTDSTPVEDPKPTEGSVILQLYKLF
ASAQGYEDMVRGFQNGGCGYGDFKKRLFDAYWEYFRPARERRAELEANQDYVRRTLEEGARKARETASVVLDRVRRAVGL
A

Sequences:

>Translated_321_residues
MRIITGLQPSGKLHVGNYFGAMEPAVRMQESGESFYFLADYHAMSTVHDANALRENCSNLATDFLAVGLDPEKCVFFRQS
AVPEVNELAWILSTVCPMGLLERCHSYKDKIAKGFSPSNALFTYPVLMAADILMYDSDLVPVGKDQKQHLEVTRDLAGKM
NEQFGEGTCKLPDALIAESTAIVPGLDGQKMSKSYNNTLPIFGEEKAVRKLIMRIPTDSTPVEDPKPTEGSVILQLYKLF
ASAQGYEDMVRGFQNGGCGYGDFKKRLFDAYWEYFRPARERRAELEANQDYVRRTLEEGARKARETASVVLDRVRRAVGL
A
>Mature_321_residues
MRIITGLQPSGKLHVGNYFGAMEPAVRMQESGESFYFLADYHAMSTVHDANALRENCSNLATDFLAVGLDPEKCVFFRQS
AVPEVNELAWILSTVCPMGLLERCHSYKDKIAKGFSPSNALFTYPVLMAADILMYDSDLVPVGKDQKQHLEVTRDLAGKM
NEQFGEGTCKLPDALIAESTAIVPGLDGQKMSKSYNNTLPIFGEEKAVRKLIMRIPTDSTPVEDPKPTEGSVILQLYKLF
ASAQGYEDMVRGFQNGGCGYGDFKKRLFDAYWEYFRPARERRAELEANQDYVRRTLEEGARKARETASVVLDRVRRAVGL
A

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=328, Percent_Identity=33.8414634146341, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI41352700, Length=167, Percent_Identity=43.1137724550898, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1789786, Length=326, Percent_Identity=37.7300613496933, Blast_Score=191, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71982800, Length=332, Percent_Identity=32.8313253012048, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71982793, Length=329, Percent_Identity=31.306990881459, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=32.7586206896552, Blast_Score=156, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24666151, Length=326, Percent_Identity=32.2085889570552, Blast_Score=156, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 35863; Mature: 35863

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIITGLQPSGKLHVGNYFGAMEPAVRMQESGESFYFLADYHAMSTVHDANALRENCSNL
CCEECCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
ATDFLAVGLDPEKCVFFRQSAVPEVNELAWILSTVCPMGLLERCHSYKDKIAKGFSPSNA
HHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LFTYPVLMAADILMYDSDLVPVGKDQKQHLEVTRDLAGKMNEQFGEGTCKLPDALIAEST
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCC
AIVPGLDGQKMSKSYNNTLPIFGEEKAVRKLIMRIPTDSTPVEDPKPTEGSVILQLYKLF
CCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ASAQGYEDMVRGFQNGGCGYGDFKKRLFDAYWEYFRPARERRAELEANQDYVRRTLEEGA
HCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RKARETASVVLDRVRRAVGLA
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIITGLQPSGKLHVGNYFGAMEPAVRMQESGESFYFLADYHAMSTVHDANALRENCSNL
CCEECCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
ATDFLAVGLDPEKCVFFRQSAVPEVNELAWILSTVCPMGLLERCHSYKDKIAKGFSPSNA
HHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LFTYPVLMAADILMYDSDLVPVGKDQKQHLEVTRDLAGKMNEQFGEGTCKLPDALIAEST
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCC
AIVPGLDGQKMSKSYNNTLPIFGEEKAVRKLIMRIPTDSTPVEDPKPTEGSVILQLYKLF
CCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
ASAQGYEDMVRGFQNGGCGYGDFKKRLFDAYWEYFRPARERRAELEANQDYVRRTLEEGA
HCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RKARETASVVLDRVRRAVGLA
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]