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The map label for this gene is ssaB [H]

Identifier: 187734568

GI number: 187734568

Start: 73252

End: 74193

Strand: Direct

Name: ssaB [H]

Synonym: Amuc_0053

Alternate gene names: 187734568

Gene position: 73252-74193 (Clockwise)

Preceding gene: 187734564

Following gene: 187734569

Centisome position: 2.75

GC content: 60.51

Gene sequence:

>942_bases
ATGCGGAACATGCTCCGGCGCATTTTGATTCCTTTTCTGTGTCTTCTGGGCCTGTTCTGCTCTCTTCAGGCCCAGGATGC
CCCAGTATTGAAAATCGCGGTTCTGCACCCCGTCTTGGGAGACATGGCCCGCGCCATCGGCGGCAGCCGCGTGCAGGTGG
CGGACCTGCTGCGCCCCAACGGCAACCTGCACAGCTTTGAACCCTCGCCGCAGGACATTGCCGCCGCAGGACGGGCGCGC
CTGGTGCTGGCCTCCGGCAAAAACCTGGAGCCGTACCTTCCCAAATTAAAGGACGCCCTGGGAGGCAGCGCGCAAATTCT
GGATCTCGGAGCCTCCGTCCCGGATGTTCCCGTGGAGGAAGACACCGCAGACCATGACCACGAACACGACGGAGACTGCT
GCGCCCACGGTCCCAACGATCCCCACTGGTGGCACACACCGGCCAATATGAAACGCGCCGCCCGCACCCTGGCCGCAACG
CTCACGCGGCTGGACCCGGACCATGAACAGGACTATAAAGTCGGCTTGTCCCGGTGGAACAGAAAGATGGACCAGCTTTC
CTCCTGGGCCAGAAAGGAACTTGCGGACATTCCGGAAACGGACCGCGTCCTGGTTACGGGGCATGCGGCCATGAACCATT
TCTGCAGGGAATTCGGCTTCCGCAGCATCAGCATCCAGGGGATAAGCCGTGAAGATGAAGGCAACTCCGCCCAGCTGGCC
TCCACGCTGAAAAAGCTGAGGTCAGCCGGGGTAAAAGCCCTGTTCCCGGAATATTCCTCCAACCCCAAGAGCCTTACGGA
AATCGCCAAATCCCTGAACATCCCCGTTGCCAGACCAATCAATACCGACGGGCTGGCCCCTGAGGGCCACACGTTCGAAT
CCATGTTCAGACAAAACACAGGCATCATCAAGGAAGCCCTTTCCCCGTCTCCCAGGCCATGA

Upstream 100 bases:

>100_bases
GAAAAACAAAAAAGGGCCGTGCAGAATCCCTGAAAAGTCAGCGTCATCCCATTTCAGAAGACAAATTTGACCATTGCATC
ACTTGAAGGGAAGGTTCATC

Downstream 100 bases:

>100_bases
CCAGCACACCCCTGCGGCAGTTTTTTCCCACTCTGGGAGTCGTCATCCTGCTGGGATTCTTCCTCTACAACATGACGGCA
CCCACCACCGGATCACAGGA

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Adhesin B; Saliva-binding protein [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRNMLRRILIPFLCLLGLFCSLQAQDAPVLKIAVLHPVLGDMARAIGGSRVQVADLLRPNGNLHSFEPSPQDIAAAGRAR
LVLASGKNLEPYLPKLKDALGGSAQILDLGASVPDVPVEEDTADHDHEHDGDCCAHGPNDPHWWHTPANMKRAARTLAAT
LTRLDPDHEQDYKVGLSRWNRKMDQLSSWARKELADIPETDRVLVTGHAAMNHFCREFGFRSISIQGISREDEGNSAQLA
STLKKLRSAGVKALFPEYSSNPKSLTEIAKSLNIPVARPINTDGLAPEGHTFESMFRQNTGIIKEALSPSPRP

Sequences:

>Translated_313_residues
MRNMLRRILIPFLCLLGLFCSLQAQDAPVLKIAVLHPVLGDMARAIGGSRVQVADLLRPNGNLHSFEPSPQDIAAAGRAR
LVLASGKNLEPYLPKLKDALGGSAQILDLGASVPDVPVEEDTADHDHEHDGDCCAHGPNDPHWWHTPANMKRAARTLAAT
LTRLDPDHEQDYKVGLSRWNRKMDQLSSWARKELADIPETDRVLVTGHAAMNHFCREFGFRSISIQGISREDEGNSAQLA
STLKKLRSAGVKALFPEYSSNPKSLTEIAKSLNIPVARPINTDGLAPEGHTFESMFRQNTGIIKEALSPSPRP
>Mature_313_residues
MRNMLRRILIPFLCLLGLFCSLQAQDAPVLKIAVLHPVLGDMARAIGGSRVQVADLLRPNGNLHSFEPSPQDIAAAGRAR
LVLASGKNLEPYLPKLKDALGGSAQILDLGASVPDVPVEEDTADHDHEHDGDCCAHGPNDPHWWHTPANMKRAARTLAAT
LTRLDPDHEQDYKVGLSRWNRKMDQLSSWARKELADIPETDRVLVTGHAAMNHFCREFGFRSISIQGISREDEGNSAQLA
STLKKLRSAGVKALFPEYSSNPKSLTEIAKSLNIPVARPINTDGLAPEGHTFESMFRQNTGIIKEALSPSPRP

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in the pathogenesis and infection. It may contribute to the formation and accumulation of dental

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34287; Mature: 34287

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNMLRRILIPFLCLLGLFCSLQAQDAPVLKIAVLHPVLGDMARAIGGSRVQVADLLRPN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHHHCCC
GNLHSFEPSPQDIAAAGRARLVLASGKNLEPYLPKLKDALGGSAQILDLGASVPDVPVEE
CCCCCCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
DTADHDHEHDGDCCAHGPNDPHWWHTPANMKRAARTLAATLTRLDPDHEQDYKVGLSRWN
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RKMDQLSSWARKELADIPETDRVLVTGHAAMNHFCREFGFRSISIQGISREDEGNSAQLA
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
STLKKLRSAGVKALFPEYSSNPKSLTEIAKSLNIPVARPINTDGLAPEGHTFESMFRQNT
HHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
GIIKEALSPSPRP
HHHHHHCCCCCCC
>Mature Secondary Structure
MRNMLRRILIPFLCLLGLFCSLQAQDAPVLKIAVLHPVLGDMARAIGGSRVQVADLLRPN
CHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHHHCCC
GNLHSFEPSPQDIAAAGRARLVLASGKNLEPYLPKLKDALGGSAQILDLGASVPDVPVEE
CCCCCCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
DTADHDHEHDGDCCAHGPNDPHWWHTPANMKRAARTLAATLTRLDPDHEQDYKVGLSRWN
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RKMDQLSSWARKELADIPETDRVLVTGHAAMNHFCREFGFRSISIQGISREDEGNSAQLA
HHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHH
STLKKLRSAGVKALFPEYSSNPKSLTEIAKSLNIPVARPINTDGLAPEGHTFESMFRQNT
HHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCC
GIIKEALSPSPRP
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1671775; 8419308 [H]