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The map label for this gene is dnaA [H]

Identifier: 187734518

GI number: 187734518

Start: 1882

End: 3288

Strand: Direct

Name: dnaA [H]

Synonym: Amuc_0002

Alternate gene names: 187734518

Gene position: 1882-3288 (Clockwise)

Preceding gene: NA

Following gene: 187734519

Centisome position: 0.07

GC content: 57.5

Gene sequence:

>1407_bases
ATGACTCCGCCATCAGAACTGTCAGCCACCTGGTCCAAAATCACGGGAGCCTTGCAAACAATCATGTCCCCGGAGGTTTA
TGGATTGTGGTTTCCCAAGTTTTCCCTGCTGGAGGATTCAGGGAAGGCGCTGACGCTGGTATGCGACGATCCTATGGCCG
CCCTCTGGGTGGAAAACAGCTATACGCCGGAGCTGAAGCAGGCCGCCATGCTGGCTCTGGGCACGGAACGCCAGATCAAA
TTCGTCTGCACAGATGAAGTGGCTTCCATGCCCGCTGCAGAAGGCCAGCCGCAAAAAGCTTCTTCCCGGGCCAAAACGCC
GCAGGCGGCGGATTCCCCGGCCGCACCGGTCAAAAAACAGCGTACATCGGCCGCCAGGGCATGCCTGAATGACTTATATA
CGTTCGATTCGTTCGTGGTGTATGAGGACAGCCGTTTTGCGTACCAGGCCGGACTGTCCGTCGCCCAGTCGGAACGGGCC
CTGTTCAATCCACTTTTCCTGTACGGTAAATCCGGCGTTGGCAAAACCCATCTTCTCCAGGCCATTGGCCATGAGGTGCT
CCATCAGGATTCATCCACAAATGTGGTGTACGTCACGGGCGAACAGTTCGCCAATGAATTTATTGACGCTTCCCGAACCC
AGAACGGACAAAGCTTCACCAAACTGCGCCGCAAGTACCGCAAGGCAGACGTCCTGCTGGTGGACGACGTGCAATTTATC
TCCGGCAAGGAAAAAACGGTGGAAGAATTCCTGCATACGTTTGACGAACTGTTCCATGCCCACAAAACCATCGTGATTTG
CGCGGATGCCGCCGCATGCGATATTTCCAATCTGGACCCCCGGCTGGCGGCGCGCCTGGAATCAGGCCTTACGGTAGAAT
TGAACCTTCCGGACGACAATGCACGGCTGGAGATCCTGCGCAGCAAGCGCGACCGGGCCGGCATGAACGTATCCGACGAA
ATTCTGGAGTTTCTGGCAAGCCGCATCCAGAAGAGCGTGCGCCGCCTGGAAGGAGCACTGCTCCGTGTAGCCACCTTTAC
TTCCCTGTCCGGAGACATGCCTGACATCGCCAAAATTGAGCAGCTTTTACGCGACATCCTGCGGGAAGAAACAAGCCGCA
TCCTGACCGTAGATTCCATCCAGAAGCGCGTGGCGGATTTTTACGAACTCAAGGTCAGCGACCTGACCGGCAAGCGCCGC
CCCAACAGCATCGCCTTTCCGCGCCAGATCGCCATGTACTTGAGCCGCCGCCTGACGGAACGCTCCCTGAAGGATATCGG
CCAGGCGTTCGGCGGCCGGGATCACGGCACCGTCATCCATGCGAACAAGCTGGTCGCCTCCCGTATGGAAGAGGATGTGC
GCGTGAGGGATATCGTCCAGAGGCTGGAAGAGGAGTTGAGGGATTGA

Upstream 100 bases:

>100_bases
CGGATGAACCTGATCCGGTTCCATCCGCGGGCGGCCTCGTAGCGGGACGGAACGCCTTACGGCTATTTCTAACCAGCAAC
ATCTTTTATTTCCAATAACA

Downstream 100 bases:

>100_bases
TTTTCCTTCCCTCCAGCCCTGCTGGAAAAGCATGGTCCCGTTGAATGCCCATGGCTTTTCAAGCGGAAGAAGCGCTTCCG
CGGCGCAGGGGAGAATAAGC

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTPPSELSATWSKITGALQTIMSPEVYGLWFPKFSLLEDSGKALTLVCDDPMAALWVENSYTPELKQAAMLALGTERQIK
FVCTDEVASMPAAEGQPQKASSRAKTPQAADSPAAPVKKQRTSAARACLNDLYTFDSFVVYEDSRFAYQAGLSVAQSERA
LFNPLFLYGKSGVGKTHLLQAIGHEVLHQDSSTNVVYVTGEQFANEFIDASRTQNGQSFTKLRRKYRKADVLLVDDVQFI
SGKEKTVEEFLHTFDELFHAHKTIVICADAAACDISNLDPRLAARLESGLTVELNLPDDNARLEILRSKRDRAGMNVSDE
ILEFLASRIQKSVRRLEGALLRVATFTSLSGDMPDIAKIEQLLRDILREETSRILTVDSIQKRVADFYELKVSDLTGKRR
PNSIAFPRQIAMYLSRRLTERSLKDIGQAFGGRDHGTVIHANKLVASRMEEDVRVRDIVQRLEEELRD

Sequences:

>Translated_468_residues
MTPPSELSATWSKITGALQTIMSPEVYGLWFPKFSLLEDSGKALTLVCDDPMAALWVENSYTPELKQAAMLALGTERQIK
FVCTDEVASMPAAEGQPQKASSRAKTPQAADSPAAPVKKQRTSAARACLNDLYTFDSFVVYEDSRFAYQAGLSVAQSERA
LFNPLFLYGKSGVGKTHLLQAIGHEVLHQDSSTNVVYVTGEQFANEFIDASRTQNGQSFTKLRRKYRKADVLLVDDVQFI
SGKEKTVEEFLHTFDELFHAHKTIVICADAAACDISNLDPRLAARLESGLTVELNLPDDNARLEILRSKRDRAGMNVSDE
ILEFLASRIQKSVRRLEGALLRVATFTSLSGDMPDIAKIEQLLRDILREETSRILTVDSIQKRVADFYELKVSDLTGKRR
PNSIAFPRQIAMYLSRRLTERSLKDIGQAFGGRDHGTVIHANKLVASRMEEDVRVRDIVQRLEEELRD
>Mature_467_residues
TPPSELSATWSKITGALQTIMSPEVYGLWFPKFSLLEDSGKALTLVCDDPMAALWVENSYTPELKQAAMLALGTERQIKF
VCTDEVASMPAAEGQPQKASSRAKTPQAADSPAAPVKKQRTSAARACLNDLYTFDSFVVYEDSRFAYQAGLSVAQSERAL
FNPLFLYGKSGVGKTHLLQAIGHEVLHQDSSTNVVYVTGEQFANEFIDASRTQNGQSFTKLRRKYRKADVLLVDDVQFIS
GKEKTVEEFLHTFDELFHAHKTIVICADAAACDISNLDPRLAARLESGLTVELNLPDDNARLEILRSKRDRAGMNVSDEI
LEFLASRIQKSVRRLEGALLRVATFTSLSGDMPDIAKIEQLLRDILREETSRILTVDSIQKRVADFYELKVSDLTGKRRP
NSIAFPRQIAMYLSRRLTERSLKDIGQAFGGRDHGTVIHANKLVASRMEEDVRVRDIVQRLEEELRD

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=462, Percent_Identity=33.982683982684, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 52309; Mature: 52178

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPSELSATWSKITGALQTIMSPEVYGLWFPKFSLLEDSGKALTLVCDDPMAALWVENS
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCEEEEEECCCCEEEEECCC
YTPELKQAAMLALGTERQIKFVCTDEVASMPAAEGQPQKASSRAKTPQAADSPAAPVKKQ
CCHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHH
RTSAARACLNDLYTFDSFVVYEDSRFAYQAGLSVAQSERALFNPLFLYGKSGVGKTHLLQ
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCHHHHHHHHHHCHHHEECCCCCCHHHHHH
AIGHEVLHQDSSTNVVYVTGEQFANEFIDASRTQNGQSFTKLRRKYRKADVLLVDDVQFI
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECHHHH
SGKEKTVEEFLHTFDELFHAHKTIVICADAAACDISNLDPRLAARLESGLTVELNLPDDN
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCCC
ARLEILRSKRDRAGMNVSDEILEFLASRIQKSVRRLEGALLRVATFTSLSGDMPDIAKIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QLLRDILREETSRILTVDSIQKRVADFYELKVSDLTGKRRPNSIAFPRQIAMYLSRRLTE
HHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
RSLKDIGQAFGGRDHGTVIHANKLVASRMEEDVRVRDIVQRLEEELRD
HHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPSELSATWSKITGALQTIMSPEVYGLWFPKFSLLEDSGKALTLVCDDPMAALWVENS
CCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCCEEEEEECCCCEEEEECCC
YTPELKQAAMLALGTERQIKFVCTDEVASMPAAEGQPQKASSRAKTPQAADSPAAPVKKQ
CCHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHH
RTSAARACLNDLYTFDSFVVYEDSRFAYQAGLSVAQSERALFNPLFLYGKSGVGKTHLLQ
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCHHHHHHHHHHCHHHEECCCCCCHHHHHH
AIGHEVLHQDSSTNVVYVTGEQFANEFIDASRTQNGQSFTKLRRKYRKADVLLVDDVQFI
HHHHHHHCCCCCCCEEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECHHHH
SGKEKTVEEFLHTFDELFHAHKTIVICADAAACDISNLDPRLAARLESGLTVELNLPDDN
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCCC
ARLEILRSKRDRAGMNVSDEILEFLASRIQKSVRRLEGALLRVATFTSLSGDMPDIAKIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QLLRDILREETSRILTVDSIQKRVADFYELKVSDLTGKRRPNSIAFPRQIAMYLSRRLTE
HHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
RSLKDIGQAFGGRDHGTVIHANKLVASRMEEDVRVRDIVQRLEEELRD
HHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA