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The map label for this gene is gap

Identifier: 187734227

GI number: 187734227

Start: 1492762

End: 1493415

Strand: Reverse

Name: gap

Synonym: SbBS512_E1636

Alternate gene names: 187734227

Gene position: 1493415-1492762 (Counterclockwise)

Preceding gene: 187733008

Following gene: 187731729

Centisome position: 32.35

GC content: 50.0

Gene sequence:

>654_bases
GTGTTGATTTCCGCCCCTGCCGGTGAAATGAAAACTATCGTTTATAACGTCAATGACGACACTCTGGATGGCAACGACAC
CATTGTTTCCGTGGCGTCATGCACCACTAACTGCCTTGCGCCGATGGCCAAAGCCTTGCATGACAGTTTCGGGATAGAAG
TCGGCACGATGACGACCATTCATGCCTATACTGGCACCCAGTCACTGGTGGATGGCCCACGTGGTAAAGATTTACGTGCT
TCACGCGCAGCGGCAGAAAATATCATTCCCCACACTACGGGGGCGGCAAAAGCCATTGGTCTGGAGATCCCGGAACTGAG
CGGCAAACTGAAAGGTCATGCGCAACGCGTGCCGGTGAAAACAGGTTCGGTCACTGAACTGGTATCGATTCTCGGAAAAA
AAGTGACTGCCGAAGAGGTGAATAACGCACTTAAACAAGCAACCACCAATAACGAGTCATTTGGTTATACCGATGAAGAA
ATAGTCTCTTCCGATATCATTGGCAGCCATTTCGGTTCGGTGTTTGATGCTACGCAAACGGAAATTACCGCCGTGGGCGA
TTTACAACTGGTGAAAACGGTCGCCTGGTACGATAACGAATATGGCTTCGTCACGCAGCTTATTCGCACCCTCGAAAAAT
TCGCTAAACTCTGA

Upstream 100 bases:

>100_bases
TCCGTGGAAAGCGAAAGGTGCAGAAATCATTGTCGAATGTACTGGCTTTTATACCTCCGCCGAGAAATCGCAGGCGCATC
TTGATGCTGGTGCGAAGAAG

Downstream 100 bases:

>100_bases
CGCGTACAGGCGGAGGAAAAAACCTCCGCCTCTTTTACTCATTACGACTGTAAATAAACCACCTGGGTCTGCAGATATTC
ATGCAGGCCATGTTTACCAT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH-C [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRA
SRAAAENIIPHTTGAAKAIGLEIPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEE
IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL

Sequences:

>Translated_217_residues
MLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRA
SRAAAENIIPHTTGAAKAIGLEIPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEE
IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
>Mature_217_residues
MLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRA
SRAAAENIIPHTTGAAKAIGLEIPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEE
IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=217, Percent_Identity=45.1612903225806, Blast_Score=180, Evalue=7e-46,
Organism=Homo sapiens, GI7657116, Length=217, Percent_Identity=45.1612903225806, Blast_Score=174, Evalue=4e-44,
Organism=Escherichia coli, GI1788079, Length=206, Percent_Identity=47.5728155339806, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1789295, Length=201, Percent_Identity=38.3084577114428, Blast_Score=131, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17568413, Length=218, Percent_Identity=44.0366972477064, Blast_Score=176, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI32566163, Length=218, Percent_Identity=44.0366972477064, Blast_Score=176, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17534677, Length=211, Percent_Identity=45.4976303317536, Blast_Score=176, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17534679, Length=211, Percent_Identity=45.0236966824645, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321631, Length=219, Percent_Identity=45.662100456621, Blast_Score=188, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6322468, Length=219, Percent_Identity=45.662100456621, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322409, Length=219, Percent_Identity=44.7488584474886, Blast_Score=184, Evalue=1e-47,
Organism=Drosophila melanogaster, GI19922412, Length=210, Percent_Identity=45.7142857142857, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI85725000, Length=214, Percent_Identity=46.2616822429907, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI22023983, Length=214, Percent_Identity=46.2616822429907, Blast_Score=180, Evalue=7e-46,
Organism=Drosophila melanogaster, GI17933600, Length=214, Percent_Identity=45.7943925233645, Blast_Score=180, Evalue=8e-46,
Organism=Drosophila melanogaster, GI18110149, Length=214, Percent_Identity=45.7943925233645, Blast_Score=180, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 23090; Mature: 23090

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTI
CEECCCCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEECCEEEE
HAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLEIPELSGKLKGHAQRVPVK
EEECCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCEECCCC
TGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQT
CCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
EITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
HEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTI
CEECCCCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEECCEEEE
HAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLEIPELSGKLKGHAQRVPVK
EEECCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCEECCCC
TGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQT
CCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
EITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
HEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]