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The map label for this gene is psuT

Identifier: 187734164

GI number: 187734164

Start: 751109

End: 752359

Strand: Direct

Name: psuT

Synonym: SbBS512_E0801

Alternate gene names: 187734164

Gene position: 751109-752359 (Clockwise)

Preceding gene: 187732277

Following gene: 187733106

Centisome position: 16.27

GC content: 50.76

Gene sequence:

>1251_bases
ATGGATATAATGAGAAGTGTTGTGGGGATGGTGGTGTTACTGGCAATAGCATTTCTGTTGTCAGTGAATAAAAAGAGCAT
CAGTTTGCGCACGGTTGGAGCCGCACTGCTGCTGCAAATCGCTATTGGTGGCATCATGCTCTACTTCCCACCGGGAAAGT
GGGCAGTAGAACAGGCGGCATTAGGCGTTCATAAAGTGATGTCTTACAGTGATGCCGGTAGCGCCTTCATTTTTGGTTCG
CTGGTTGGGCCGAAAATGGATGTCCTGTTTGACGGTGCGGGTTTTATCTTCGCCTTTCGCGTACTTCCGGCGATTATTTT
CGTTACTGCGCTCATCAGTCTGCTGTACTACATTGGCGTGATGGGGCTGCTGATTCGCATCCTTGGCAGCATTTTCCAGA
AAGCTCTTAACATCAGCAAAATCGAATCTTTTGTCGCAGTCACAACTATTTTCCTCGGGCAAAATGAGATCCCGGCGATC
GTTAAACCGTTTATCGATCGCATGAATCGCAACGAGTTGTTTACCGCAATTTGTAGCGGGATGGCGTCCATTGCTGGTTC
GATGATGATTGGTTATGCCGGAATGGGCGTACCAATTGACTACCTGTTAGCGGCATCGCTGATGGCGATCCCAGGTGGTA
TTTTGTTTGCACGTATTCTTAGCCCGGCCACCGAGCCTTCGCAGGTCACATTTGAAAATCTGTCGTTCAGCGAAACGCCG
CCAAAAAGCTTTATCGAAGCGGCGGCGAGCGGTGCGATGACCGGGCTGAAAATCGCCGCTGGTGTAGCGACGGTGGTAAT
GGCGTTTGTCGCAATTATTGCGCTGATCAACGGCATTATCGGCGGAATTGGTGGCTGGTTTGGTTTCGCCAATGCCTCTC
TGGAAAGTATTTTTGGCTATGTGCTGGCACCGCTGGCGTGGATCATGGGTGTGGACTGGAGTGATGCCAATCTTGCGGGT
AGCCTGATTGGGCAGAAACTGGCGATTAACGAATTCGTCGCTTACCTGAGTTTCTCCCCATACCTGCAAACGGGCGGCAC
GCTGGAAGTGAAAACCATTGCGATTATCTCCTTTGCGCTTTGTGGTTTTGCTAACTTTGGTTCTATCGGTGTTGTCGTTG
GCGCATTTTCGGCTATTTCGCCAAAACGCGCGCCGGAAATCGCCCAGCTTGGTTTACGGGCGCTGGCAGCAGCAACGCTT
TCCAACCTGATGAGTGCGACTATTGCCGGGTTCTTTATTGGTTTAGCTTGA

Upstream 100 bases:

>100_bases
GGGTTAATTTCTGACGGGCAGAAAGCCGTCGCCCGTACTCATCAAGCATACCAAAACCTGGCGCTGACGCCGGGTTTACT
GGCATGAAGGGAAAATCATT

Downstream 100 bases:

>100_bases
GTTTCATTGCCGGATGTACGCGCTTATTAAGCGTTGCATCCGGCAATCGCGCTAGGTAATGACTCCAACTTACTGATAGT
GTTTTATGTTCAGATAATGC

Product: nucleoside transporter, NupC family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA

Sequences:

>Translated_416_residues
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA
>Mature_416_residues
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA

Specific function: Could be involved in pseudouridine transport

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family

Homologues:

Organism=Homo sapiens, GI11545853, Length=415, Percent_Identity=33.2530120481928, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI42542381, Length=418, Percent_Identity=32.2966507177034, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI227116277, Length=419, Percent_Identity=30.0715990453461, Blast_Score=201, Evalue=1e-51,
Organism=Escherichia coli, GI1788488, Length=416, Percent_Identity=100, Blast_Score=808, Evalue=0.0,
Organism=Escherichia coli, GI1788485, Length=416, Percent_Identity=88.2211538461538, Blast_Score=707, Evalue=0.0,
Organism=Escherichia coli, GI1788737, Length=412, Percent_Identity=30.5825242718447, Blast_Score=184, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17560276, Length=396, Percent_Identity=28.2828282828283, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71991794, Length=399, Percent_Identity=29.0726817042606, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI25146537, Length=194, Percent_Identity=28.8659793814433, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45552517, Length=408, Percent_Identity=30.8823529411765, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI45552519, Length=408, Percent_Identity=30.8823529411765, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI19921868, Length=408, Percent_Identity=30.8823529411765, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI281360430, Length=407, Percent_Identity=30.958230958231, Blast_Score=194, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSUT_ECOLI (P33024)

Other databases:

- EMBL:   U00007
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64985
- RefSeq:   AP_002761.1
- RefSeq:   NP_416669.1
- ProteinModelPortal:   P33024
- DIP:   DIP-11925N
- MINT:   MINT-1248538
- STRING:   P33024
- EnsemblBacteria:   EBESCT00000004597
- EnsemblBacteria:   EBESCT00000017214
- GeneID:   946671
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2151
- KEGG:   eco:b2164
- EchoBASE:   EB1967
- EcoGene:   EG12032
- eggNOG:   COG1972
- GeneTree:   EBGT00050000009760
- HOGENOM:   HBG713614
- OMA:   WIIRIIG
- ProtClustDB:   CLSK880317
- BioCyc:   EcoCyc:YEIM-MONOMER
- Genevestigator:   P33024
- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668
- PANTHER:   PTHR10590
- TIGRFAMs:   TIGR00804

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N

EC number: NA

Molecular weight: Translated: 43432; Mature: 43432

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bbfed4c)-; HASH(0x1ad914bc)-; HASH(0x1cd40fdc)-; HASH(0x1acfcac8)-; HASH(0x1bc222cc)-; HASH(0x1cbe2874)-; HASH(0x1cc72b6c)-; HASH(0x1b8dee84)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHH
LGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGV
HHHHHHHHCCCCCCCEEEHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRMNRNELFTAICSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHH
MASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCCCCC
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFAL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEHHHHHHHHHHH
CGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
HCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGGIMLYFPPGKWAVEQAA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHH
LGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGV
HHHHHHHHCCCCCCCEEEHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRMNRNELFTAICSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHH
MASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATEPSQVTFENLSFSETP
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCCCCC
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFAL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEHHHHHHHHHHH
CGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA
HCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503