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The map label for this gene is ybeM [H]

Identifier: 187733191

GI number: 187733191

Start: 517062

End: 517850

Strand: Direct

Name: ybeM [H]

Synonym: SbBS512_E0540

Alternate gene names: 187733191

Gene position: 517062-517850 (Clockwise)

Preceding gene: 187731707

Following gene: 187732695

Centisome position: 11.2

GC content: 53.74

Gene sequence:

>789_bases
ATGCTGGTTGCTGCAGGACAGTTTGCTGTTACATCTGTGTGGGAAAAGAACGCTGAGATTTGTGCCTCGTTGATGGCGCA
GGCGGCGGAAAACGACGTATCGCTGTTTGTCCTGCCGGAAGCATTGCTGGCACGCGATGATCATGATGCAGATCTATCGG
TTAAATCAGCACAGCTGCTGGAAGGCGAATTCCTCGGACGTTTACGGCGAGAAAGTAAACGTAACATGATGACGACAATT
CTGACGATTCATGTTCCTTCAACGCCGGGGCGCGCATGGAATATGCTGGTGGCACTTCAGGCAGGAAACATCGTCGCCCG
TTATGCCAAACTGTATCTCTATGATGCATTTGCCATTCAGGAATCACGCCGTGTTGATGCTGGTAATGAAATCGCTCCGT
TACTGGAGGTGGAAGGGATGAAGGTCGGTCTGATGACCTGTTATGACTTACGCTTTCCAGAGCTGGCGCTGGCACAGGCA
TTACAGGGAGCTGAAATCCTGGTACTTCCTGCCGCCTGGGTTCGCGGGCCGCTCAAAGAGCATCACTGGTCAACGTTGCT
TGCCGCTCGTGCGCTGGATACCACCTGTTATATGGTGGCGGCGGGCGAGTGCGGGAACAAAAATATCGGGCAAAGCCGGA
TTATAGATCCCTTTGGCGTCACCATTGCGGCAGCGTCAGAAATGCCTGCACTCATTATGGCGGAAGTGACGCCCGAACGT
GTGCGTCAGGTGCGCGCGCAACTGCCCGTCTTAAACAACCGTCGCTTTGCGCCGCCGCAATTATTATGA

Upstream 100 bases:

>100_bases
TGTAACACTGCAAAATCCTGCTATTTGATTTGTATGAGTGATAAGTGTAACGCCGAATAATCGTCGTTGGCGAATTTTAC
GACTCTGACAGGAGGTGACA

Downstream 100 bases:

>100_bases
TGTTTTTTTACTCGGCGCTTGATTCACCTTGTTACAGATTGCTATTGTGTGCGCGCGTCGAATGACCGTTAATATTCTCT
GGTTTTTAAGGCGCGTTCTG

Product: hydrolase, carbon-nitrogen family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTI
LTIHVPSTPGRAWNMLVALQAGNIVARYAKLYLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
VRQVRAQLPVLNNRRFAPPQLL

Sequences:

>Translated_262_residues
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTI
LTIHVPSTPGRAWNMLVALQAGNIVARYAKLYLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
VRQVRAQLPVLNNRRFAPPQLL
>Mature_262_residues
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTI
LTIHVPSTPGRAWNMLVALQAGNIVARYAKLYLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
VRQVRAQLPVLNNRRFAPPQLL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=279, Percent_Identity=35.1254480286738, Blast_Score=131, Evalue=5e-31,
Organism=Homo sapiens, GI297632350, Length=279, Percent_Identity=35.1254480286738, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI297632348, Length=279, Percent_Identity=35.1254480286738, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI9910460, Length=262, Percent_Identity=25.5725190839695, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI297632346, Length=202, Percent_Identity=32.6732673267327, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=272, Percent_Identity=29.4117647058824, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322335, Length=297, Percent_Identity=29.6296296296296, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323383, Length=250, Percent_Identity=27.6, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355835, Length=168, Percent_Identity=31.547619047619, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17933642, Length=267, Percent_Identity=29.2134831460674, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28708; Mature: 28708

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLL
CEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECHHHHCCCCCCCCCEEHHHHHH
EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLYLYDAFAIQ
HHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
HCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHCCCEEEEECHHHHCCCHHH
HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
HHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHH
VRQVRAQLPVLNNRRFAPPQLL
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLARDDHDADLSVKSAQLL
CEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECHHHHCCCCCCCCCEEHHHHHH
EGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAGNIVARYAKLYLYDAFAIQ
HHHHHHHHHHHHHHCEEEEEEEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHH
ESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQALQGAEILVLPAAWVRGPLKE
HCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHCCCEEEEECHHHHCCCHHH
HHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPFGVTIAAASEMPALIMAEVTPER
HHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCHHH
VRQVRAQLPVLNNRRFAPPQLL
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]