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The map label for this gene is yghZ [H]

Identifier: 187732579

GI number: 187732579

Start: 3190567

End: 3191607

Strand: Direct

Name: yghZ [H]

Synonym: SbBS512_E3430

Alternate gene names: 187732579

Gene position: 3190567-3191607 (Clockwise)

Preceding gene: 187731088

Following gene: 187733502

Centisome position: 69.12

GC content: 51.87

Gene sequence:

>1041_bases
ATGGTCTGGTTAGCGAATCCCGAACGTTACGGGCAGATGCAGTACCGCTATTGCGGAAAAAGTGGTTTACGCCTGCCCGC
GTTATCGCTCGGTTTATGGCACAATTTCGGTCACGTTAACGCGCTGGAATCACAGCGTGCAATCCTGCGTAAAGCGTTTG
ATTTAGGCATTACGCACTTTGATTTAGCCAACAATTACGGGCCGCCTCCAGGAAGCGCAGAAGAGAACTTTGGTCGCCTG
CTGCGGGAGGATTTTGCCGCTTATCGCGATGAACTGATTATCTCTACCAAGGCTGGCTACGATATGTGGCCCGGCCCTTA
CGGCTCTGGCGGTTCACGTAAATACCTGCTCGCCAGCCTCGACCAAAGCCTGAAGCGTATGGGGCTTGAGTATGTCGATA
TCTTTTACTCTCATCGCGTCGATGAAAATACGCCGATGGAAGAAACCGCCTCTGCGCTGGCTCATGCGGTACAAAGCGGT
AAGGCGCTGTATGCCGGGATCTCCTCTTACTCGCCAGAGCGGACGCAAAAAATGGTCGAGTTGCTGCACGAGTGGAAAAT
TCCGCTTTTAATTCATCAACCTTCGTACAATTTACTGAACCGCTGGGTGGATAAAAGCGGCCTGCTGGATACCCTGCAAA
ATAACGGCGTGGGCTGTATTGCCTTTACTCCTCTGGCTCAGGGATTGCTGACCGGAAAATATCTCAACGGCATACCGCAA
GATTCACGGATGCATCGTGAAGGGAATAAAGTTCGTGGTCTGACGCCGAAAATGCTTACCGAAGCCAACCTCAACAGCCT
GCGCTTATTGAATGAAATGGCACAGCAGCGTGGACAATCAATGGCGCAAATGGCGTTAAGCTGGTTGCTGAAAAATGATC
GCGTGACGTCGGTATTGATTGGTGTCAGCCGCGCGGAGCAACTAGAGGAGAACGTGCAGGCGCTGAATAATCTGACATTT
AGCACCGAGGAGCTGGCGCAGATTGATCAGCATATCGCCGATGGCGAGCTGAATCTGTGGCAGGCGTCTTCCGATAAATG
A

Upstream 100 bases:

>100_bases
CAGTTTTTCGTCACTCTGTGAGCCAGACTACGGGATACGCGCTGGCGAATCGCTAAACTAGAAACATTGTTTCGAAATTG
AACGGTGGAAAGGAGAGGTC

Downstream 100 bases:

>100_bases
CTTGTTAATAACGGGCGCGCGAACCGCGCCCGAATCAGATCAGTGATTATGACGAGTCAGTCGGTCAAGATAGCCCATCA
CAAATGCAGAGAGCACAAAC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYAGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKNDRVTSVLIGVSRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Sequences:

>Translated_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYAGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKNDRVTSVLIGVSRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>Mature_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYAGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKNDRVTSVLIGVSRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504825, Length=338, Percent_Identity=35.207100591716, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=34.9544072948328, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=34.5679012345679, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=34.5679012345679, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=34.2592592592593, Blast_Score=171, Evalue=6e-43,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=33.7423312883436, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI41152114, Length=211, Percent_Identity=31.7535545023697, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI41327764, Length=213, Percent_Identity=30.5164319248826, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=28.6713286713287, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=98.5549132947977, Blast_Score=705, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=36.0606060606061, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=23.8390092879257, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=23.7388724035608, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=315, Percent_Identity=24.7619047619048, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=238, Percent_Identity=24.7899159663866, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322615, Length=238, Percent_Identity=24.3697478991597, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=27.8260869565217, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=27.8260869565217, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646155, Length=322, Percent_Identity=26.3975155279503, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38814; Mature: 38814

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYAGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECHHCCCHHHHHHHHH
LLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKNDRVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GVSRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYAGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECHHCCCHHHHHHHHH
LLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPQ
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKNDRVTSVLI
CHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GVSRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]