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The map label for this gene is sorM [H]

Identifier: 187732311

GI number: 187732311

Start: 4226443

End: 4227597

Strand: Reverse

Name: sorM [H]

Synonym: SbBS512_E4517

Alternate gene names: 187732311

Gene position: 4227597-4226443 (Counterclockwise)

Preceding gene: 187734152

Following gene: 187732226

Centisome position: 91.59

GC content: 54.37

Gene sequence:

>1155_bases
ATGGAACAGAGAAAAATTACACGCAGCGATCTGGTGAGCATGTTTCTGCGCTCCAACCTGCAACAGGCGTCCTTTAACTT
TGAACGTATTCACGGGCTGGGTTTTTGCTACGACATGATCCCCGCCATCAAACGACTTTACCCATTAAAAGAGGATCAGG
TTGCGGCGCTCAGGCGACACCTGGTGTTCTTCAATACCACGCCAGCCGTATGTGGCCCGGTCATCGGCGTCACTGCCGCC
ATGGAAGAGGCGCGGGCCAACGGCGCGGAAATTGATGACGGTACCATTAACGGCATCAAAGTCGGTCTGATGGGACTATT
GGCAGGAGTTGGCGATCCACTGGTCTGGGGAACGCTGCGCCCGATTACCACCGCGCTCGGCGCATCTCTGGCACTTTCGG
GCAACATTCTCGGCCCGCTGCTGTTCTTCTTTATTTTCAATGCGGTGCGTCTGGCGATGAAGTGGTATGGCCTACAGCTC
GGCTTTCGCAAAGGGGTGAATATCGTCAGCGATATGGGCGGGAATGTGCTGCAAAAACTCACCGAAGGCGCGTCGATTCT
CGGGCTGTTTGTGATGGGCGTGCTGGTCACCAAATGGACGTCAATCAACGTACCGTTGGTGGTTTCACAAACGCATGCCG
CCGATGGCTCCACCGTCACCATGACCGTGCAGAACATTCTCGACCAACTTTGCCCTGGTTTGCTGGCGCTCGGTCTGACG
CTGCTTATGGTTCGTCTGCTCAACAAAAAAATTAACCCGGTATGGCTGATTTTCGCCCTGTTTGGCTTAGGGATTATCGG
TAATGCGCTGGGCTTCCTGTCCAGATTCTTCGCCCCGGCACGACTGCCGGGGCCATCGCTCAACATGAGGTGGTTTATGA
AAACAACAGCTCTGCGTCTTTATGGTAAACGTGATTTACGCCTGGAAACCTTTGACCTTCCTGAAATGCAGGAGGATGAA
ATCCTCGCGACGGTGGTCACTGACAGCCTGTGCCTCTCTTCCTGGAAAGAGGCCAATCTGGGTGAAAACCATAAAAAAGT
ACCCGACGATGTGGCGCCCCCCCCCCCATCATCATCGGCCACGAGTTTTGCGGCGATATTCTGGCCGTGGGTAAAAAGTG
GCAGCACAAATTCCAGCCGGGTCAGCGTTATGTGA

Upstream 100 bases:

>100_bases
GTCTACATCCAGCTAAATCCACAGTGGCGTAAAGCTGAACCTCAACTCCAGGCCACCGCCTCCACCGCCCTTGACCAACT
TGACGATTAACGGAGCCATC

Downstream 100 bases:

>100_bases
TTCAGGCCAACCTGCAACTCCCCGACCGCCCGGACTGCCCCGGCTACTCCTTCCCGTGGGTGGGCGGCGAAGCCACGCAT
GTGGTTATTCCCAACGAGGT

Product: PTS system mannose/fructose/sorbose family IID

Products: protein histidine; sugar phosphate; D-glucosamine-6-phosphate [Cytoplasm]; pyruvate; glucose-6-phosphate [Cytoplasm]; N-acetyl-D-glucosamine-6-phosphate [Cytoplasm]; mannose-6-phosphate [Cytoplasm]; fructose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIID-Sor; PTS system sorbose-specific EIID component [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGLLAGVGDPLVWGTLRPITTALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLSRFFAPARLPGPSLNMRWFMKTTALRLYGKRDLRLETFDLPEMQEDE
ILATVVTDSLCLSSWKEANLGENHKKVPDDVAPPPPSSSATSFAAIFWPWVKSGSTNSSRVSVM

Sequences:

>Translated_384_residues
MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGLLAGVGDPLVWGTLRPITTALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLSRFFAPARLPGPSLNMRWFMKTTALRLYGKRDLRLETFDLPEMQEDE
ILATVVTDSLCLSSWKEANLGENHKKVPDDVAPPPPSSSATSFAAIFWPWVKSGSTNSSRVSVM
>Mature_384_residues
MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGLLAGVGDPLVWGTLRPITTALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLSRFFAPARLPGPSLNMRWFMKTTALRLYGKRDLRLETFDLPEMQEDE
ILATVVTDSLCLSSWKEANLGENHKKVPDDVAPPPPSSSATSFAAIFWPWVKSGSTNSSRVSVM

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3716

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIID domain [H]

Homologues:

Organism=Escherichia coli, GI1788122, Length=272, Percent_Identity=61.7647058823529, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI1789529, Length=274, Percent_Identity=36.1313868613139, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI48994910, Length=63, Percent_Identity=53.968253968254, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004704
- InterPro:   IPR018405 [H]

Pfam domain/function: PF03613 EIID-AGA [H]

EC number: NA

Molecular weight: Translated: 41857; Mature: 41857

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS51108 PTS_EIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRH
CCCCHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGLLAGVGDPLVWGTLR
HEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCHH
PITTALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVSDMGGNVLQKL
HHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHH
TEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
HCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLSRFFAPARLPGPSLNMRWFMKTTALRL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHH
YGKRDLRLETFDLPEMQEDEILATVVTDSLCLSSWKEANLGENHKKVPDDVAPPPPSSSA
HCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
TSFAAIFWPWVKSGSTNSSRVSVM
CHHHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure
MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPLKEDQVAALRRH
CCCCHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVGLMGLLAGVGDPLVWGTLR
HEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCHH
PITTALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQLGFRKGVNIVSDMGGNVLQKL
HHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHH
TEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
HCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLSRFFAPARLPGPSLNMRWFMKTTALRL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHH
YGKRDLRLETFDLPEMQEDEILATVVTDSLCLSSWKEANLGENHKKVPDDVAPPPPSSSA
HCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
TSFAAIFWPWVKSGSTNSSRVSVM
CHHHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N p -phosphohistidine; sugar; phosphoenolpyruvate; glucosamine [Periplasm]; phosphoenolpyruvate; beta-D-glucose [Periplasm]; N-acetyl-D-glucosamine [Periplasm]; mannose [Periplasm]; fructose [Periplasm] [C]

Specific reaction: protein N p -phosphohistidine + sugar = protein histidine + sugar phosphate phosphoenolpyruvate + glucosamine [Periplasm] = D-glucosamine-6-phosphate [Cytoplasm] + pyruvate phosphoenolpyruvate + beta-D-glucose [Periplasm] = glucose-6-phosphate [Cytoplasm]

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7947968 [H]