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The map label for this gene is rstA

Identifier: 187731773

GI number: 187731773

Start: 1638245

End: 1638973

Strand: Direct

Name: rstA

Synonym: SbBS512_E1794

Alternate gene names: 187731773

Gene position: 1638245-1638973 (Clockwise)

Preceding gene: 187730080

Following gene: 187731289

Centisome position: 35.49

GC content: 49.11

Gene sequence:

>729_bases
ATGAACACTATCGTATTTGTGGAAGATGATGCGGAAGTCGGTTCACTGATTGCCGCGTACCTGGCAAAACATGATATGCA
GGTTACCGTAGAGCCGCGCGGCGACCAGGCCGAAGAAACCATTTTGCGAGAAAATCCGGATTTGGTGTTACTCGACATCA
TGCTACCAGGCAAGGACGGCATGACCATTTGTCGTGATTTACGCGCAAAGTGGTCTGGACCGATTGTTCTTCTAACCTCT
CTCGATAGCGATATGAACCACATCCTGGCACTGGAAATGGGTGCCTGCGACTATATTCTCAAAACGATGCCCCCTGCTGT
TTTGCTAGCGCGTTTACGTTTGCATTTGCGTCAGAATGAGCAAGCCACACTGACCAAAGGTCTTCAGGAAACGTCTCTGA
CGTCTCTGACTCCCTACAAAGCCCTGCATTTCGGCACGTTGACCATCGATCCCATCAACCGCGTAGTCACCCTGGCTAAC
ACTGAAATCTCGCTCTCGACAGCTGATTTCGAATTATTGTGGGAATTAGCTACCCATGCCGGGCAAATCATGGACCGCGA
TGCATTGCTGAAAAATTTACGCGGCGTCAGTTATGACGGACTGGATCGTAACGTGGACGTGGCTATTTCGCGGTTAAGAA
AAAAACTGCTCGATAACGCCGCAGAACCTTATCGCATTAAAACTGTGCGTAACAAAGGCTATCTTTTTGCGCCTCATGCA
TGGGAATAA

Upstream 100 bases:

>100_bases
TCATCAGTAGAATACCTGATGAAAACTTGTTTAGAAACGATTGATAGTAAGTAAAAACAGCGCGGTGTATTGTGACGTTT
TTATATCTACCGTGAATGTT

Downstream 100 bases:

>100_bases
GCGATGAAAAAACTGTTTATCCAGTTTTACCTGTTATTGTTTGTCTGCTTCCTTGTGATGTCTCTGCTGGTTGGGTTGGT
GTACAAATTTACCGCCGAAC

Product: DNA-binding transcriptional regulator RstA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTS
LDSDMNHILALEMGACDYILKTMPPAVLLARLRLHLRQNEQATLTKGLQETSLTSLTPYKALHFGTLTIDPINRVVTLAN
TEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRNVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
WE

Sequences:

>Translated_242_residues
MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTS
LDSDMNHILALEMGACDYILKTMPPAVLLARLRLHLRQNEQATLTKGLQETSLTSLTPYKALHFGTLTIDPINRVVTLAN
TEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRNVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
WE
>Mature_242_residues
MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTS
LDSDMNHILALEMGACDYILKTMPPAVLLARLRLHLRQNEQATLTKGLQETSLTSLTPYKALHFGTLTIDPINRVVTLAN
TEISLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRNVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
WE

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=242, Percent_Identity=97.9338842975207, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=34.3220338983051, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=32.1888412017167, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=32.0512820512821, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=32.6271186440678, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786599, Length=237, Percent_Identity=28.6919831223629, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=29.3617021276596, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786911, Length=237, Percent_Identity=28.2700421940928, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=27.3504273504274, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=30.4721030042918, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=29.3617021276596, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787375, Length=244, Percent_Identity=27.4590163934426, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790552, Length=236, Percent_Identity=28.3898305084746, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27063; Mature: 27063

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDG
CCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEEECCCCC
MTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKTMPPAVLLARLRLHLRQNE
HHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHCCCC
QATLTKGLQETSLTSLTPYKALHFGTLTIDPINRVVTLANTEISLSTADFELLWELATHA
HHHHHHCHHHHCCCCCCCCHHEEEEEEEECCCCEEEEEECCEEEEEHHHHHHHHHHHHHH
GQIMDRDALLKNLRGVSYDGLDRNVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCC
WE
CC
>Mature Secondary Structure
MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDG
CCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEEECCCCC
MTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKTMPPAVLLARLRLHLRQNE
HHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHCCCC
QATLTKGLQETSLTSLTPYKALHFGTLTIDPINRVVTLANTEISLSTADFELLWELATHA
HHHHHHCHHHHCCCCCCCCHHEEEEEEEECCCCEEEEEECCEEEEEHHHHHHHHHHHHHH
GQIMDRDALLKNLRGVSYDGLDRNVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCC
WE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]