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The map label for this gene is luxS

Identifier: 187731215

GI number: 187731215

Start: 2978127

End: 2978642

Strand: Direct

Name: luxS

Synonym: SbBS512_E3189

Alternate gene names: 187731215

Gene position: 2978127-2978642 (Clockwise)

Preceding gene: 187732538

Following gene: 187731062

Centisome position: 64.52

GC content: 51.55

Gene sequence:

>516_bases
ATGCCGTTGTTAGATAGCTTCACAGTCGATCATACCCGGATGGAAGCGCCTGCAGTTCGGGTGGCGAAAACAATGAACAC
CCCGCATGGCGACGCAATCACCGTGTTCGATCTGCGCTTCTGCGTGCCGAACAAAGAAGTGATGCCAGAAAGAGGGAGCC
ATACTCTGGAGCACCTGTTTGCTGGTTTTATGCGTAACCATCTTAACGGTAATGGTGTAGAGATTATCGATATCTCGCCA
ATGGGCTGCCGCACCGGTTTTTATATGAGTCTGATTGGTACGCCAGATGAGCAGCGTGTTGCTGATGCCTGGAAAGCGGC
AATGGAAGACGTGCTGAAAGTGCAGGATCAGAATCAGATCCCGGAGCTGAACGTCTACCAGTGTGGCACTTACCAGATGC
ACTCGTTGCAGGAAGCGCAGGATATTGCGCGTAGCATTCTGGAACGTGACGTACGCATCAACAGCAACGAAGAACTGGCA
CTGCCGAAAGAGAAGTTGCAGGAACTGCACATTTAG

Upstream 100 bases:

>100_bases
TCAGGGATGATGATAACAAATGCGCGTCTTTCATATACTCAGACTCGCCTGGGAAGAAAGAGTTCAGAAAATTTTTAAAA
AAATTACCGGAGGTGGCTAA

Downstream 100 bases:

>100_bases
TCAGTAAACTATCTTCACAATTAATTGAAAAAAGCCAGTTCAAATGAACTGGCTTAGTTGTACTTAGTGCGCACCACCTC
CGCCGCCACCTGCGCCAAAG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGSHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
LPKEKLQELHI

Sequences:

>Translated_171_residues
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGSHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
LPKEKLQELHI
>Mature_170_residues
PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGSHTLEHLFAGFMRNHLNGNGVEIIDISPM
GCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELAL
PKEKLQELHI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=171, Percent_Identity=99.4152046783626, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 19390; Mature: 19259

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGSHTLEHLF
CCCCCCCCCCHHHHHCHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHH
AGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQI
HHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
CCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGSHTLEHLF
CCCCCCCCCHHHHHCHHHHHHHHCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHH
AGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQI
HHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
PELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
CCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA