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The map label for this gene is actP

Identifier: 187730956

GI number: 187730956

Start: 4281971

End: 4283620

Strand: Reverse

Name: actP

Synonym: SbBS512_E4586

Alternate gene names: 187730956

Gene position: 4283620-4281971 (Counterclockwise)

Preceding gene: 187731192

Following gene: 187733077

Centisome position: 92.8

GC content: 55.15

Gene sequence:

>1650_bases
ATGAAAAGAGTTCTGACGGCGCTTGCCGCCACACTCCCTTTCGCAGCTAACGCCGCGGATGCTATTAGCGGGGCCGTAGA
GCGCCAGCCAACGAACTGGCAGGCGATTATTATGTTCCTGATTTTCGTCGTGTTTACGCTCGGCATTACCTACTGGGCAT
CAAAACGCGTACGTTCTCGTAGCGACTACTACACGGCAGGCGGCAATATCACAGGCTTCCAGAACGGGCTGGCGATTGCC
GGTGACTATATGTCCGCCGCCTCATTTTTGGGGATCTCCGCGCTGGTGTTTACCTCCGGCTATGACGGCTTAATTTACTC
GCTGGGCTTCCTGGTGGGCTGGCCGATCATTTTGTTCCTGATTGCCGAACGTCTGCGTAACCTGGGACGCTACACCTTTG
CCGATGTAGCCTCTTACCGCCTGAAACAAGGGCCGATTCGTATTCTTTCGGCCTGTGGTTCTCTGGTGGTGGTGGCGCTT
TACCTTATCGCCCAGATGGTAGGCGCAGGTAAACTGATCGAGCTGCTGTTTGGCCTTAACTATCACATTGCGGTGGTGCT
GGTCGGCGTGCTGATGATGATGTACGTCCTGTTCGGCGGCATGCTGGCGACCACCTGGGTGCAAATTATTAAAGCCGTGC
TGTTGCTGTTCGGTGCCAGCTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAATAATCTGTTCAGCGAA
GCGATGGCGGTACACCCGAAAGGTGTCGACATCATGAAGCCGGGCGGGCTGGTGAAAGATCCGATCTCCGCGCTCTCTCT
GGGTCTGGGACTGATGTTTGGTACGGCGGGCTTGCCGCACATTCTGATGCGCTTCTTTACAGTCAGCGATGCCCGCGAAG
CACGTAAGAGCGTGTTCTACGCCACCGGGTTTATGGGCTACTTCTATATTCTGACCTTTATTATCGGCTTCGGCGCGATC
ATGCTGGTTGGTGCGAATCCGGAATATAAAGACGCGGCGGGCCATCTGATTGGTGGTAACAACATGGCGGCCGTTCACCT
GGCGAATGCAGTGGGCGGCAACCTGTTCCTCGGTTTTATTTCAGCGGTTGCTTTCGCCACTATCCTCGCGGTGGTTGCGG
GTCTGACGCTGGCGGGCGCATCCGCGGTTTCGCATGACTTGTTCGCTAACGTCTTCAAAAAAGGTGCGACCGAACGTGAA
GAACTGCGGGTATCGAAAATCACCGTCCTGATTTTGGGTGTGATTGCGATTATCCTCGGCGTGCTGTTTGAGAATCAGAA
CATCGCCTTTATGGTAGGCCTTGCGTTTGCCATCGCGGCGAGCTGTAACTTCCCGATCATTCTGCTTTCCATGTACTGGT
CGAAACTGACTACCCGTGGCACGATGCTGGGCGGCTGGCTGGGGCTGATTACCGCAGTGGTGCTGATGATCCTCGGCCCA
ACTATTTGGGTACAGATCCTCGGTCACGAAAAAGCCATCTTCCCGTATGAATACCCGGCGCTGTTCTCTATCAGCGTGGC
ATTCCTCGGCATCTGGTTCTTCTCGGCAACCGATAACTCAGCGGAAGGTGCGCGCGAGCGTGAACTGTTCCGTGCGCAGT
TTATCCGCTCCCAGACCGGCTTTGGCGTTGAGCAAGGCCGCGCACATTAA

Upstream 100 bases:

>100_bases
TGATTGTGATCTCCTTTGTTCTCACCGGTATCTACATCTGGCGGGCGAACGGCGAATTCGACCGTCTTAATAATGAAGTC
CTGCATGAGGTACAAGCATC

Downstream 100 bases:

>100_bases
TCTCTCCCCTTCCCCGGTCGCCTGACCGGGGAATACTCTTCCTCTCCAGCATGGGTAATGACTCCAACTTACTGATAGTG
TTTTATGTTCAGATAATGCC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLFANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGTMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

Sequences:

>Translated_549_residues
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLFANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGTMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
>Mature_549_residues
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLFANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGTMLGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=469, Percent_Identity=26.226012793177, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1790503, Length=549, Percent_Identity=99.2714025500911, Blast_Score=1087, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=451, Percent_Identity=25.9423503325942, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 59180; Mature: 59180

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCC
>Mature Secondary Structure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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA