BacMap

Definition	Shigella boydii CDC 3083-94 chromosome, complete genome.
Accession	NC_010658
Length	4,615,997

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The map label for this gene is mglA

Identifier: 187730811

GI number: 187730811

Start: 768806

End: 769810

Strand: Direct

Name: mglA

Synonym: SbBS512_E0817

Alternate gene names: 187730811

Gene position: 768806-769810 (Clockwise)

Preceding gene: 187732107

Following gene: 187733299

Centisome position: 16.66

GC content: 46.17

Gene sequence:

>1005_bases
ATGGTCAGCTCAACGACTCCGTCCTCCGGGGAATACTTGTTGGAAATGAGCGGTATCAACAAGTCCTTTCCTGGTGTTAA
GGCACTTGATAACGTTAATTTAAAAGTCCGGCCACATTCTATCCATGCATTAATGGGGGAAAACGGCGCAGGAAAATCAA
CATTATTAAAATGCTTGTTTGGTATTTATCAAAAAGACTCCGGCACCATTTTATTCCAGGGTAAAGAGATCGATTTCCAT
TCGGCCAAAGAAGCACTGGAAAATGGTATTTCGATGGTACACCAGGAGTTAAACCTGGTATTACAACGTTCGGTGATGGA
CAACATGTGGCTTGGGCGATACCCCACCAAAGGCATGTTTGTCGATCAGGACAAAATGTACCGCGAAACCAAAGCGATTT
TTGATGAACTGGATATTGATATCGATCCGCGTGCGCGCGTCGGCACATTATCTGTTTCGCAAATGCAGATGATCGAAATC
GCCAAAGCGTTTTCCTATAACGCGAAAATTGTGATTATGGATGAACCGACTTCTTCGTTAACCGAAAAAGAGGTCAATCA
TCTGTTCACTATTATTCGTAAATTAAAAGAGCGCGGCTGCGGTATTGTTTATATCTCGCATAAAATGGAGGAAATCTTCC
AGTTATGTGATGAAGTTACCGTATTGCGCGACGGTCAGTGGATCGCCACCGAACCGCTGGCAGGACTGACGATGGACAAG
ATCATCGCCATGATGGTTGGGCGTTCTCTTAACCAGCGTTTCCCTGACAAAGAAAACAAGCCGGGCGAAGTCATCCTCGA
GGTGCGTAACCTGACGTCACTGCGCCAGCCGTCGATCCGTGATGTCTCGTTTGATCTGCATAAAGGGGAGATCCTCGGTA
TTGCCGGGCTGATGGGGGCGAAACGTACCGATATTGTTGAGACGTTATTTGGTATTCGCGAGAAATCGGCCGGCACCATT
ACGTTGCACGGCAAAAAGATCAATAACCATAATGCCAATGGGTAA

Upstream 100 bases:

>100_bases
CGTAGATAAAGACAACCTGGCTGAATTCAGCAAGAAATAAGACTGATTGGGCGCAGTCTATTACTGCGCCCTTATTGTAT
GACCAACAAGGTAAAATTAT

Downstream 100 bases:

>100_bases
TGACTCCAACTTACTGATAGTGTTTTATGTTCAGATAATGCCCGATGACCTTGTCATGCAGCTCCACCGATTTTGAGAAC
GACAGTGACTTCCGTCCCAG

Product: galactoside ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFH
SAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDK
IIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLMGAKRTDIVETLFGIREKSAGTI
TLHGKKINNHNANG

Sequences:

>Translated_334_residues
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFH
SAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDK
IIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLMGAKRTDIVETLFGIREKSAGTI
TLHGKKINNHNANG
>Mature_334_residues
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFH
SAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDK
IIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLMGAKRTDIVETLFGIREKSAGTI
TLHGKKINNHNANG

Specific function: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system [H]

COG id: COG1129

COG function: function code G; ABC-type sugar transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI30795238, Length=251, Percent_Identity=26.2948207171315, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI105990541, Length=202, Percent_Identity=28.2178217821782, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI31657092, Length=218, Percent_Identity=26.1467889908257, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI47078218, Length=199, Percent_Identity=24.1206030150754, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI45446740, Length=199, Percent_Identity=24.1206030150754, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI21729873, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI15149474, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9961252, Length=227, Percent_Identity=28.6343612334802, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9961250, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4505771, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9955963, Length=218, Percent_Identity=27.5229357798165, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI255708477, Length=226, Percent_Identity=26.5486725663717, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788472, Length=333, Percent_Identity=99.3993993993994, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI1790190, Length=318, Percent_Identity=48.1132075471698, Blast_Score=313, Evalue=7e-87,
Organism=Escherichia coli, GI1789991, Length=330, Percent_Identity=42.4242424242424, Blast_Score=264, Evalue=7e-72,
Organism=Escherichia coli, GI1790525, Length=323, Percent_Identity=42.4148606811146, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1788210, Length=317, Percent_Identity=39.7476340694006, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI48995001, Length=327, Percent_Identity=34.8623853211009, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1788897, Length=313, Percent_Identity=37.3801916932907, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1787792, Length=330, Percent_Identity=35.1515151515151, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1786398, Length=223, Percent_Identity=28.6995515695067, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=28.099173553719, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082268, Length=240, Percent_Identity=27.9166666666667, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786319, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=25.2252252252252, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789593, Length=218, Percent_Identity=26.605504587156, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081791, Length=222, Percent_Identity=26.5765765765766, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788506, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786345, Length=238, Percent_Identity=30.2521008403361, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787029, Length=201, Percent_Identity=25.8706467661692, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787089, Length=220, Percent_Identity=25.9090909090909, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789672, Length=230, Percent_Identity=24.7826086956522, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=27.3148148148148, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787370, Length=221, Percent_Identity=24.8868778280543, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786654, Length=208, Percent_Identity=30.2884615384615, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787712, Length=216, Percent_Identity=23.6111111111111, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789873, Length=217, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790739, Length=223, Percent_Identity=26.457399103139, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081709, Length=215, Percent_Identity=25.5813953488372, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788450, Length=244, Percent_Identity=28.2786885245902, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789891, Length=222, Percent_Identity=25.2252252252252, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693107, Length=372, Percent_Identity=24.4623655913978, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786253, Length=187, Percent_Identity=29.9465240641711, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790544, Length=231, Percent_Identity=25.974025974026, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081782, Length=225, Percent_Identity=25.7777777777778, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=22.4669603524229, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787143, Length=221, Percent_Identity=28.9592760180996, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787758, Length=231, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786698, Length=217, Percent_Identity=26.2672811059908, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787759, Length=256, Percent_Identity=28.90625, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994943, Length=338, Percent_Identity=22.7810650887574, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081834, Length=214, Percent_Identity=25.7009345794392, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786803, Length=203, Percent_Identity=26.6009852216749, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787548, Length=226, Percent_Identity=26.9911504424779, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789032, Length=260, Percent_Identity=25.7692307692308, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788644, Length=223, Percent_Identity=25.1121076233184, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI2367384, Length=209, Percent_Identity=26.7942583732057, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790467, Length=218, Percent_Identity=25.2293577981651, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786872, Length=190, Percent_Identity=24.2105263157895, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082267, Length=214, Percent_Identity=27.1028037383178, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=200, Percent_Identity=28.5, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=238, Percent_Identity=30.672268907563, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=207, Percent_Identity=29.4685990338164, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=200, Percent_Identity=28.5, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324985, Length=213, Percent_Identity=28.6384976525822, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323959, Length=208, Percent_Identity=28.3653846153846, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512771, Length=220, Percent_Identity=27.7272727272727, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666092, Length=213, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571209, Length=226, Percent_Identity=26.9911504424779, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24659289, Length=219, Percent_Identity=29.2237442922374, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550390, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI23397593, Length=211, Percent_Identity=27.0142180094787, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136662, Length=210, Percent_Identity=29.5238095238095, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI19920532, Length=254, Percent_Identity=26.7716535433071, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24580930, Length=254, Percent_Identity=26.7716535433071, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015862
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.17 [H]

Molecular weight: Translated: 37316; Mature: 37316

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLF
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHH
GIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMF
HHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
VDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSL
ECHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHH
TEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDK
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEECCCEEECCCCCCCCHHH
IIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLMGA
HHHHHHCCHHHHCCCCCCCCCCCEEEEEHHHHHHCCCCCCCEEEECCCCCEEEEHHHCCC
KRTDIVETLFGIREKSAGTITLHGKKINNHNANG
CHHHHHHHHHHHHCCCCCEEEEECEEECCCCCCC
>Mature Secondary Structure
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLF
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHH
GIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMF
HHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
VDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSL
ECHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEEECCCHHH
TEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDK
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEECCCEEECCCCCCCCHHH
IIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLMGA
HHHHHHCCHHHHCCCCCCCCCCCEEEEEHHHHHHCCCCCCCEEEECCCCCEEEEHHHCCC
KRTDIVETLFGIREKSAGTITLHGKKINNHNANG
CHHHHHHHHHHHHCCCCCEEEEECEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]