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The map label for this gene is mlrA [H]

Identifier: 187730391

GI number: 187730391

Start: 1136408

End: 1136947

Strand: Reverse

Name: mlrA [H]

Synonym: SbBS512_E1232

Alternate gene names: 187730391

Gene position: 1136947-1136408 (Counterclockwise)

Preceding gene: 187730869

Following gene: 187730509

Centisome position: 24.63

GC content: 53.7

Gene sequence:

>540_bases
TTGCTGAAACCGCAACGGACAGACGGCGGTCATCGGCTGTTCAACGATGCCGATATTGACCGGATCCGCGAGATCAAACG
CTGGATCGACAACGGCGTGCAGGTCAGCAAAGTTAAAATGCTGCTCAGTAATGAAAATGTTGATGTGCAGAACGGCTGGC
GCGATCAGCAAGAAACATTACTGACTTACTTGCAAAGCGGCAATCTGCATAGCCTGCGAACGTGGATCAAAGAGCGCGGT
CAGGATTACCCCGCCCAGACGCTCACCACGCATTTGTTTATTCCTCTGCGTCGACGGCTTCAGTGCCAACAACCGACTCT
CCAGGCGCTGCTGGCGATCCTCGACGGCGTACTGATCAACTACATCGCCATCTGTCTGGCTTCGGCACGTAAAAAACAGG
GTAAAGATGCGCTGGTGGTTGGCTGGAATATTCACGATACCACCCGTCTGTGGCTGGAGGGCTGGATTGCCAGTCAACAA
GGATGGCGCATTGATGTCCTCGCCCACTCGCTCAATGTAAGGCAGTATGACTTTCCGTGA

Upstream 100 bases:

>100_bases
GTATGCCCCATAAGAAAGTGGGGTAAAATAAAAACTTGTAAAATCAGTTAGTTTACCCTTAATCCCTGTCACGTTACGCG
CGTGGCAGAGGCGTTACGGA

Downstream 100 bases:

>100_bases
GACAGATGCTGGCCAACGTGGGATATTTAACGCGGGTTAACATCGTTGTCAGAGCCGCATGGGTGAGCTGTTGCTACACC
CCGGTATTTCCACCACGGAG

Product: HTH-type transcriptional regulator MlrA

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQ
GWRIDVLAHSLNVRQYDFP

Sequences:

>Translated_179_residues
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQ
GWRIDVLAHSLNVRQYDFP
>Mature_179_residues
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQ
GWRIDVLAHSLNVRQYDFP

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=172, Percent_Identity=98.8372093023256, Blast_Score=345, Evalue=8e-97,
Organism=Escherichia coli, GI1787409, Length=180, Percent_Identity=43.8888888888889, Blast_Score=162, Evalue=2e-41,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 20780; Mature: 20780

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
LTYLQSGNLHSLRTWIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLIN
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQGWRIDVLAHSLNVRQYDFP
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCC
>Mature Secondary Structure
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
LTYLQSGNLHSLRTWIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLIN
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQGWRIDVLAHSLNVRQYDFP
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]