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The map label for this gene is blr

Identifier: 187730088

GI number: 187730088

Start: 1661181

End: 1661306

Strand: Direct

Name: blr

Synonym: SbBS512_E1813

Alternate gene names: 187730088

Gene position: 1661181-1661306 (Clockwise)

Preceding gene: 187733372

Following gene: 187730877

Centisome position: 35.99

GC content: 42.86

Gene sequence:

>126_bases
ATGAATCGTCTTATTGAATTAACAGGTTGGATCGTTCTTGTCGTTTCAGTCATTCTTCTTGGCGTGGCGAGTCACATTGA
CAACTATCAGCCACCTGAACAGAGTGCTTCGGTACAACACAAGTAA

Upstream 100 bases:

>100_bases
TATCGCAAAAACCTCAGTAAAAATCTTGCTGGAGCTATTATTGCTAAGTAACATTTACCCCCTGAAGTTAATGGATCAAT
CAAGAGAGATGTGGGCTGTA

Downstream 100 bases:

>100_bases
GCTCTGCGCTTGTAGAGCGCCATGCTGCCCGTCCGGGTGCATGTTTTCACTTGTCGGATATTAAACCAGGAATTTATTAT
CTTGTTCGATGTTGTTGGTG

Product: beta-lactam resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 41; Mature: 41

Protein sequence:

>41_residues
MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK

Sequences:

>Translated_41_residues
MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK
>Mature_41_residues
MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK

Specific function: Has an effect on the susceptibiltiy to a number of antibiotics involved in peptidoglycan biosynthesis. Acts with beta lactams, D-cycloserine and bacitracin. Has no effect on the susceptibility to tetracycline, chloramphenicol, gentamicin, fosfomycin, vaco

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994886, Length=41, Percent_Identity=100, Blast_Score=84, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BLR_ECOLI (P56976)

Other databases:

- EMBL:   AF219227
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_002246.1
- RefSeq:   YP_025303.1
- ProteinModelPortal:   P56976
- STRING:   P56976
- EnsemblBacteria:   EBESCT00000004876
- EnsemblBacteria:   EBESCT00000016394
- GeneID:   2847682
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5963
- KEGG:   eco:b4409
- EcoGene:   EG14389
- GeneTree:   EBGT00050000011838
- HOGENOM:   HBG467802
- ProtClustDB:   CLSK881211
- BioCyc:   EcoCyc:MONOMER0-1561
- Genevestigator:   P56976

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 4556; Mature: 4556

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e3bbc58)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
>Mature Secondary Structure
MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10931331; 9278503