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The map label for this gene is oxaA

Identifier: 186477842

GI number: 186477842

Start: 3476508

End: 3478160

Strand: Reverse

Name: oxaA

Synonym: Bphy_3098

Alternate gene names: 186477842

Gene position: 3478160-3476508 (Counterclockwise)

Preceding gene: 186477843

Following gene: 186477840

Centisome position: 99.97

GC content: 60.19

Gene sequence:

>1653_bases
ATGGATATCAAACGCACCGTCCTATGGGTCATTTTCTTCATGTCAGCTGTCATGCTGTTCGACAACTGGCAGCGCGACCA
CGGACGCCCGTCGATGTTCTTCCCGAGCGCGACGCAGACCAAGACGGCGGCTCCCGCCGCGCCCGGCTCGTCGACGACGG
CAAGCCAACCGACAGATTTGCCGCAGACGACGGCTGCCGCACCCGGCTCGACAACGCCCGCCGCGCAGCAGGCGCAGCTG
GTTTCGTTCAGCACGGACGTCTACCGTGGCCAGATCGATACGCGGGGCGGCACGCTGTCCAAGCTCACGCTGGTCAAGCC
GGGGGAGGGCAAGCAGCCCGATCAGGTGATCACGCTGTTCGACCACACGGCCGACCACACGTATCTCGCGCGTACGGGCC
TGCTCGGCGGCGACTTCCCGAACCACACCGACGTGTTCACGCCCGTTGCCGGTCAGGCGACCGACATGACGGGCAACACA
CTGACGCTATCTTTCCAGTCGCCGGAAAAGGGTGGCCTGAAGGTCGTGAAGACATACACCTTCACGCGTGGCAGCTATGT
GATCAATGTCGATACGAAAATCCAGAACGTCGGCACGGCGCCCGTCAAGCCGACCGCGTACATGGAACTCGTGCGCGACA
GTCAGCCCGTCGAAACGCCGCGCTTCTCGCACACGTTCATCGGGCCGGCGGTGTACACGGAACAGCATCACTTCCAGAAG
CTGACGTTCGGCGACATCGACAAGAACAAGCAGGACTATGCCACTTCGGCCGACAACGGCTGGGTCGCGATGGTGCAGCA
CTATTTTGCATCTGCGTGGATTCCGCAGCAGGGCGCAAAGCGTGACATCTACGTCGAGAAGATCGATCCGTCGCTCTATC
GCGTCGGCGTCAAGCAGCCGTTGCAGACCATTGCGCCGGGCCAGACGATCGACGTGTCTGCGCGTCTGTTCGCCGGTCCG
GAAGAAGAACGCATGCTCGAAGGCATCGCGCCGGGTCTGGAACTGGTGAAGGACTACGGCTGGGTGACGATCATCGCGAA
GCCGCTGTTCTGGCTGCTCGAAAAGATCCACGGCTACGTCGGCAACTGGGGCTGGGCAATCGTGCTGTTGACGCTGCTGA
TCAAGGCCGTGTTCTTCCCGCTGTCGGCAGCTAGCTACAAGTCGATGGCCCGCATGAAGGAAATCACGCCGCGCATGCAG
GCGCTGCGCGAACGCTTCAAGAGCGATCCGCAGAAGATGAACGCGGCTCTGATGGAGCTGTACAAGACTGAGAAGGTCAA
TCCGTTCGGCGGCTGCCTGCCTGTCGTGATTCAGATTCCGGTCTTTATCTCGCTGTACTGGGTGCTGCTTTCGTCGGTGG
AAATGCGCGGTGCACCGTGGATTCTGTGGATTCACGATCTGTCGCAACAAGATCCGTACTTCATCCTGCCGGTTCTGATG
GCCGTCTCGATGTTCGTTCAAACGAAGCTCAACCCGACGCCGCCGGATCCTGTGCAAGCCAAGATGATGATGTTCATGCC
GATCGCGTTCTCGGTCATGTTCTTCTTCTTCCCGGCCGGTCTTGTGCTGTACTACGTCGTGAACAATGTGCTGTCGATTG
CGCAGCAGTATTACATCACGCGCATGATGGGGCAGAAGAAAAAGGCTGCCTGA

Upstream 100 bases:

>100_bases
GTGCCGCTGTCACCCGTTTTCGGCGGGCGGCATCGATCTTGTCCCGCCTCCAACTCCTAAGAAGCGCTGACGCGCTGTGC
CATCGACACTGAGACAACGC

Downstream 100 bases:

>100_bases
GCGGGCGTTCGGCGCGGACGCGTGTTTGTCCGAGCCGATGCCGAAAAAGCAAACCGCCCGGTTTCAGCCGGGCGGTTTTT
TTACGTCTTGCGATTTATCT

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATQTKTAAPAAPGSSTTASQPTDLPQTTAAAPGSTTPAAQQAQL
VSFSTDVYRGQIDTRGGTLSKLTLVKPGEGKQPDQVITLFDHTADHTYLARTGLLGGDFPNHTDVFTPVAGQATDMTGNT
LTLSFQSPEKGGLKVVKTYTFTRGSYVINVDTKIQNVGTAPVKPTAYMELVRDSQPVETPRFSHTFIGPAVYTEQHHFQK
LTFGDIDKNKQDYATSADNGWVAMVQHYFASAWIPQQGAKRDIYVEKIDPSLYRVGVKQPLQTIAPGQTIDVSARLFAGP
EEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGYVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQ
ALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPYFILPVLM
AVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRMMGQKKKAA

Sequences:

>Translated_550_residues
MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATQTKTAAPAAPGSSTTASQPTDLPQTTAAAPGSTTPAAQQAQL
VSFSTDVYRGQIDTRGGTLSKLTLVKPGEGKQPDQVITLFDHTADHTYLARTGLLGGDFPNHTDVFTPVAGQATDMTGNT
LTLSFQSPEKGGLKVVKTYTFTRGSYVINVDTKIQNVGTAPVKPTAYMELVRDSQPVETPRFSHTFIGPAVYTEQHHFQK
LTFGDIDKNKQDYATSADNGWVAMVQHYFASAWIPQQGAKRDIYVEKIDPSLYRVGVKQPLQTIAPGQTIDVSARLFAGP
EEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGYVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQ
ALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPYFILPVLM
AVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRMMGQKKKAA
>Mature_550_residues
MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATQTKTAAPAAPGSSTTASQPTDLPQTTAAAPGSTTPAAQQAQL
VSFSTDVYRGQIDTRGGTLSKLTLVKPGEGKQPDQVITLFDHTADHTYLARTGLLGGDFPNHTDVFTPVAGQATDMTGNT
LTLSFQSPEKGGLKVVKTYTFTRGSYVINVDTKIQNVGTAPVKPTAYMELVRDSQPVETPRFSHTFIGPAVYTEQHHFQK
LTFGDIDKNKQDYATSADNGWVAMVQHYFASAWIPQQGAKRDIYVEKIDPSLYRVGVKQPLQTIAPGQTIDVSARLFAGP
EEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGYVGNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQ
ALRERFKSDPQKMNAALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPYFILPVLM
AVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRMMGQKKKAA

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=568, Percent_Identity=35.2112676056338, Blast_Score=376, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24662345, Length=194, Percent_Identity=25.2577319587629, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356443, Length=194, Percent_Identity=25.2577319587629, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_BURP8 (B2JJR8)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001859312.1
- ProteinModelPortal:   B2JJR8
- SMR:   B2JJR8
- GeneID:   6244577
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_3098
- HOGENOM:   HBG507812
- OMA:   NVEKEAF
- ProtClustDB:   PRK01318
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 61345; Mature: 61345

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21134cdc)-; HASH(0x20e1a1fc)-; HASH(0x211e1190)-; HASH(0x212eead8)-; HASH(0x20e113e0)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATQTKTAAPAAPGSSTTASQPTDL
CCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PQTTAAAPGSTTPAAQQAQLVSFSTDVYRGQIDTRGGTLSKLTLVKPGEGKQPDQVITLF
CCCCCCCCCCCCCCHHHHHHHEECHHHHCCEEECCCCCEEEEEEECCCCCCCCCCEEEEE
DHTADHTYLARTGLLGGDFPNHTDVFTPVAGQATDMTGNTLTLSFQSPEKGGLKVVKTYT
ECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEE
FTRGSYVINVDTKIQNVGTAPVKPTAYMELVRDSQPVETPRFSHTFIGPAVYTEQHHFQK
EECCCEEEEECCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCHHCCCCHHHHC
LTFGDIDKNKQDYATSADNGWVAMVQHYFASAWIPQQGAKRDIYVEKIDPSLYRVGVKQP
CCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHH
LQTIAPGQTIDVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGYV
HHHHCCCCEEEECCCEECCCCHHHHHHHHCHHHHHHHHCCHHEEHHHHHHHHHHHHHHHH
GNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMEL
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPYFILPVLM
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEHHHHHH
AVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYIT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMMGQKKKAA
HHHCCCCCCH
>Mature Secondary Structure
MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATQTKTAAPAAPGSSTTASQPTDL
CCHHHHHHHHHHHHHHHHHHHCCHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCC
PQTTAAAPGSTTPAAQQAQLVSFSTDVYRGQIDTRGGTLSKLTLVKPGEGKQPDQVITLF
CCCCCCCCCCCCCCHHHHHHHEECHHHHCCEEECCCCCEEEEEEECCCCCCCCCCEEEEE
DHTADHTYLARTGLLGGDFPNHTDVFTPVAGQATDMTGNTLTLSFQSPEKGGLKVVKTYT
ECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEE
FTRGSYVINVDTKIQNVGTAPVKPTAYMELVRDSQPVETPRFSHTFIGPAVYTEQHHFQK
EECCCEEEEECCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCHHCCCCHHHHC
LTFGDIDKNKQDYATSADNGWVAMVQHYFASAWIPQQGAKRDIYVEKIDPSLYRVGVKQP
CCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHH
LQTIAPGQTIDVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHGYV
HHHHCCCCEEEECCCEECCCCHHHHHHHHCHHHHHHHHCCHHEEHHHHHHHHHHHHHHHH
GNWGWAIVLLTLLIKAVFFPLSAASYKSMARMKEITPRMQALRERFKSDPQKMNAALMEL
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPYFILPVLM
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEHHHHHH
AVSMFVQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYIT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMMGQKKKAA
HHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA