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The map label for this gene is atpB [H]

Identifier: 186477779

GI number: 186477779

Start: 3406880

End: 3407731

Strand: Reverse

Name: atpB [H]

Synonym: Bphy_3033

Alternate gene names: 186477779

Gene position: 3407731-3406880 (Counterclockwise)

Preceding gene: 186477780

Following gene: 186477778

Centisome position: 97.95

GC content: 59.15

Gene sequence:

>852_bases
ATGGCAGCTAGCGAAGGAACGCGCGCTCTGGATCCGTCCGAGTACATTGCGCACCACTTGCAGAATTTTTCCACCGCTCA
TCAGACGTCGATCTTCGACATCCACGTCTGGAATCTCGATACGCTCTTCTGGTCGATCGTATGCGGTCTCGTCACCATCC
TGGTTCTGCGTCTCGCCGCACGTAAGGCGACGTCCGGCGTGCCGGGCCGTTTCCAGTGCGCGATCGAAATGCTGGTCGAA
ATGGTTGAGGATCAATCGAAGTCGATGATCCACGGCAATCGCGCATTCATCGCACCGCTCGCGCTGACCGTGTTTGTCTG
GGTCGCGCTGATGAACTCGCTCGACTTTCTCCCCGTCGACCTGCCGGGCCGCGTGATCGACCTGCTCGGTCTGTCGGGCG
TCATCTCGCACCACCGTATCGTTCCGACGGCCGACCTCAACGGCACGATCGGGATTGCGCTCGGCGTGTTCGTACTGATG
ATTTACTACAACTTCAAGATCAAGGGCGCTGGCGGCTTTGTGCACGAACTGCTGTCCGCTCCGTTCGGCTCGCATCCGCT
GCTGTGGATCCCGAACCTTGCACTGAACATCATCGAGTTCGTCGCGAAGACGGTCTCCCTCGGCATGCGGCTGTTCGGCA
ACATGTACGCGGGCGAGCTGTTGTTCCTGCTGATTGCCCTGCTCGGCAGCATCTGGAACTTCGGTGCGGACACGACGGTG
CTTGGCTTCATCGGCCACGTGATCGCAGGCAGCGTGTGGGCAATCTTCCACATCCTGATCGTTCTGCTGCAGGCGTTCAT
TTTCATGATGCTGACGCTGGTGTACATCGGCCAGGCACACGACGCTCACTAA

Upstream 100 bases:

>100_bases
GCGGGTTGGACAGAAGCCCGCGCTGGCGTGTTCCCGCAATACAGCATTGCGGCGGGAGCGGCCCGGGAAGATTTTCGACA
ATTTGGGTGGCATTAACGAT

Downstream 100 bases:

>100_bases
CCGGCGCGTCGCCAAAGAATCAGAGTTTCAAGAATCGTAGTTTTTTAAATCCCAGTTCCAAAAAAGACTTTTCACAAGGA
GTGATCATGCAAGCTTTCAT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAASEGTRALDPSEYIAHHLQNFSTAHQTSIFDIHVWNLDTLFWSIVCGLVTILVLRLAARKATSGVPGRFQCAIEMLVE
MVEDQSKSMIHGNRAFIAPLALTVFVWVALMNSLDFLPVDLPGRVIDLLGLSGVISHHRIVPTADLNGTIGIALGVFVLM
IYYNFKIKGAGGFVHELLSAPFGSHPLLWIPNLALNIIEFVAKTVSLGMRLFGNMYAGELLFLLIALLGSIWNFGADTTV
LGFIGHVIAGSVWAIFHILIVLLQAFIFMMLTLVYIGQAHDAH

Sequences:

>Translated_283_residues
MAASEGTRALDPSEYIAHHLQNFSTAHQTSIFDIHVWNLDTLFWSIVCGLVTILVLRLAARKATSGVPGRFQCAIEMLVE
MVEDQSKSMIHGNRAFIAPLALTVFVWVALMNSLDFLPVDLPGRVIDLLGLSGVISHHRIVPTADLNGTIGIALGVFVLM
IYYNFKIKGAGGFVHELLSAPFGSHPLLWIPNLALNIIEFVAKTVSLGMRLFGNMYAGELLFLLIALLGSIWNFGADTTV
LGFIGHVIAGSVWAIFHILIVLLQAFIFMMLTLVYIGQAHDAH
>Mature_282_residues
AASEGTRALDPSEYIAHHLQNFSTAHQTSIFDIHVWNLDTLFWSIVCGLVTILVLRLAARKATSGVPGRFQCAIEMLVEM
VEDQSKSMIHGNRAFIAPLALTVFVWVALMNSLDFLPVDLPGRVIDLLGLSGVISHHRIVPTADLNGTIGIALGVFVLMI
YYNFKIKGAGGFVHELLSAPFGSHPLLWIPNLALNIIEFVAKTVSLGMRLFGNMYAGELLFLLIALLGSIWNFGADTTVL
GFIGHVIAGSVWAIFHILIVLLQAFIFMMLTLVYIGQAHDAH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=287, Percent_Identity=45.993031358885, Blast_Score=220, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 30977; Mature: 30846

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASEGTRALDPSEYIAHHLQNFSTAHQTSIFDIHVWNLDTLFWSIVCGLVTILVLRLAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
RKATSGVPGRFQCAIEMLVEMVEDQSKSMIHGNRAFIAPLALTVFVWVALMNSLDFLPVD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPGRVIDLLGLSGVISHHRIVPTADLNGTIGIALGVFVLMIYYNFKIKGAGGFVHELLSA
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHC
PFGSHPLLWIPNLALNIIEFVAKTVSLGMRLFGNMYAGELLFLLIALLGSIWNFGADTTV
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LGFIGHVIAGSVWAIFHILIVLLQAFIFMMLTLVYIGQAHDAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AASEGTRALDPSEYIAHHLQNFSTAHQTSIFDIHVWNLDTLFWSIVCGLVTILVLRLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
RKATSGVPGRFQCAIEMLVEMVEDQSKSMIHGNRAFIAPLALTVFVWVALMNSLDFLPVD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPGRVIDLLGLSGVISHHRIVPTADLNGTIGIALGVFVLMIYYNFKIKGAGGFVHELLSA
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCHHHHHHHHC
PFGSHPLLWIPNLALNIIEFVAKTVSLGMRLFGNMYAGELLFLLIALLGSIWNFGADTTV
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LGFIGHVIAGSVWAIFHILIVLLQAFIFMMLTLVYIGQAHDAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA