Click here to switch to the map view.

The map label for this gene is 186477739

Identifier: 186477739

GI number: 186477739

Start: 3351893

End: 3354262

Strand: Reverse

Name: 186477739

Synonym: Bphy_2993

Alternate gene names: NA

Gene position: 3354262-3351893 (Counterclockwise)

Preceding gene: 186477740

Following gene: 186477738

Centisome position: 96.41

GC content: 65.27

Gene sequence:

>2370_bases
ATGCACGACATTCCGACCCTTCTGAACGCCGCGCTGACGCATCATCAGGCAGGGCGCCTCGCCGACGCGCAGGCGCTCTA
CGACGCCATTCTGCAGACCGAGCCGGCGCAATCCGACGCGCTGCATTTCTCCGGCTTGCTCGCGTGCCAGACGGATCGCG
CGGACGCGGGCATCGCGTTGATGCGCGCATCGATTGCGGCGAATCCGAATGCCGTCTACTACAACAATCTGGGCAACGTG
CTGCTCGGACGTCGTCAGCTTGGCGAAGCGATCGAAGGCTATCGGCAGGCGGTGAATCTGCGTCCCGATTACGCCGAGGC
GCACAACAATCTCGGCAATGCACTGCGGGAAGCAGGCGACGCCAACGCCGCGATGATGAGTTGCGCCACGGCGATCGAAC
TGCGGCCAGGTTACGCGGAGGCGTACAACAACCTCGGCAATGCACTGAAGGATCTCGGCGATCTCGGCAACGCGGTGCTG
GCGTATCAGAAGGCCGTGTCGTTCCGTCCGGACTATGCGGACGCGTTCGGCAATCTCGCACGCGCCGAGGCCGGGCGTGG
CGACGCGGACGCATCGATTGCCGCGTTTCGCCGCGCGCTCGCGCTCGATCCGGATCGTGCCGACAGCTACGACAGTCTCG
CGAAGCTGCTGCACGCGCGCGGTGAAATCGACGCCGCGATCGACACGTTGCAACAGGCGACGCGACGCGATCCCGCCGAT
GCCGCGCGTCATCGCTTGCTCGCGCAATGGCTGCTTGGCCGCCAGCGCTGGGACGAAGCGGCGCACGCGCTGACGAGCGC
GGTCGAACTCGCGCCCAACGACGCTGCGGGTTATGTGGAACTGGGCGACGCGTATCAGCACGCAGACAAGCTCGACGCCG
CGATCCTTTGCTATCGGACGGCCACCGAACTGGCACCCCGCGATGCGCCTGCGCACCATCGGCTCGCCGTTGCGCTCCTC
AAACAGCGCCGCGCAGACGAAGCGCTCGAGAGCGCGCAAAAGGCCGTTTCGCTCGAACCGCATTCGGCCGTACCGCACGT
GAATCTCGGCGACGTGCTGAGCGTGCTCGGCGACGCGGACGGCGCAATTGCGAGCTATCGGCGCGGCATCGCGCTCGACG
GCGAAATGGAACTCGCGCACAACCGCCTGCTGTTCGATCTCGCGACGCACGCGCCGACGCCGCCCGCCGTCACGCTCGTC
GCCGCGCGTGAATTCGGCGCGCGCATGGCCGCGCGTGCGCGCCGCTGCGAGCATCCGGCGCCGCAAGACGACGGCAGAAA
GCTGCGCATCGGTTTCGTGTCCGGCGATCTGCAACTGCATCCCGTGGGCATTTTCATCGAATCGGTGATGGAGCATTTCG
CGGACGGGAGCTTCGATCTGATCGCCTACTCGACGCGCGCAAGCGAAGACGACATCACCGCCCGCCTGAAACAGCGCTTT
ACTGCGTGGCGCAGCCTCGTGAACGTGCGCGACGAACAGGCCGTGCAGATGATTCGCGACGATGGCATCGACATACTCGT
CGATCTGTCGGGCCATACCGTGCACAACCGCCTGCCCGTGTTCGCGTGGAAACCTGCGCCCGTGCAGGTCAGCTGGCTCG
GCTATTTCGGCACGACGGGGTTGAACGAAATCGACTACGTGCTCGGCGATCCACATGTGCTGCCCGTCGCTGAAGAATCG
CACTATGTGGAGAAGACCTGGCGTCTGCCCGACAGCTACCTGTGCTTCACGCCGCCGAACGTCGATGTGGCCGTCGGCCC
GTTGCCGATGACGCTCAGCGGCCATGTCACGTTCGGCTATTTCGGCAAGCTCGTGAAGATCACGCCCAACGTGATCGCCG
CCTGGTCGCGTCTGTTGCGTGCGGTGCCGGGCGCGAAGCTGATGATGAAATCGCACGAACTCGGCGCCGCGCACGCCCGG
CGTTCGGCGGCTGAACAATTCGCCGCGCAAGGCATCGACGCATTGCGCCTCATTCTCGAAGGCGGCTCGCCGCGTCACGA
ATATCTCAAAGCATATAACCGTGTCGACATCATGCTGAGCCCGTTTCCATATCCGGGCGGCACGACGACGGCGGAAGCGC
TGTGGATGGGCACGCCCGTCGTTGCGCTTCAAGGCGATCGCTTCGTCACGCATATCTGCGAGAGCGTGCTGAACGCGGCA
GGACTCGGCGAATGGATCGCACGCGACGAAGACGAATACATCGCACTCGCGAGCGCGTGGGCCGCGCAGCGGGAGCGCCT
CGCCGTCCTGCGCGCGCGTTTGCGTGCGCAGACGCTGGCGTCGCCGCTGTGCGATGCACGGCGCTTCGCGACCAATCTGA
AAGCAGCATTCGAAGGCATGTGGGCGCAATACGTTTCGCGCGCTGCTTGA

Upstream 100 bases:

>100_bases
AAGGCATCGCCACGAAGCGCGTGATGATCGAGCACGACGGCGGCCTCGTCGACTTCTTCGCGCAGTCGCATCCCTATTGA
ACGGGCCGGGACGTTTGACC

Downstream 100 bases:

>100_bases
GGCGAAGCGGGCATGCGAGCCGCACTTCCGACGACACAAAGGATCACAGTGGATCACGCAAATCTTCTCAATACCGCGCT
CGCGCACCACCAGGCCGGCC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 789

Protein sequence:

>789_residues
MHDIPTLLNAALTHHQAGRLADAQALYDAILQTEPAQSDALHFSGLLACQTDRADAGIALMRASIAANPNAVYYNNLGNV
LLGRRQLGEAIEGYRQAVNLRPDYAEAHNNLGNALREAGDANAAMMSCATAIELRPGYAEAYNNLGNALKDLGDLGNAVL
AYQKAVSFRPDYADAFGNLARAEAGRGDADASIAAFRRALALDPDRADSYDSLAKLLHARGEIDAAIDTLQQATRRDPAD
AARHRLLAQWLLGRQRWDEAAHALTSAVELAPNDAAGYVELGDAYQHADKLDAAILCYRTATELAPRDAPAHHRLAVALL
KQRRADEALESAQKAVSLEPHSAVPHVNLGDVLSVLGDADGAIASYRRGIALDGEMELAHNRLLFDLATHAPTPPAVTLV
AAREFGARMAARARRCEHPAPQDDGRKLRIGFVSGDLQLHPVGIFIESVMEHFADGSFDLIAYSTRASEDDITARLKQRF
TAWRSLVNVRDEQAVQMIRDDGIDILVDLSGHTVHNRLPVFAWKPAPVQVSWLGYFGTTGLNEIDYVLGDPHVLPVAEES
HYVEKTWRLPDSYLCFTPPNVDVAVGPLPMTLSGHVTFGYFGKLVKITPNVIAAWSRLLRAVPGAKLMMKSHELGAAHAR
RSAAEQFAAQGIDALRLILEGGSPRHEYLKAYNRVDIMLSPFPYPGGTTTAEALWMGTPVVALQGDRFVTHICESVLNAA
GLGEWIARDEDEYIALASAWAAQRERLAVLRARLRAQTLASPLCDARRFATNLKAAFEGMWAQYVSRAA

Sequences:

>Translated_789_residues
MHDIPTLLNAALTHHQAGRLADAQALYDAILQTEPAQSDALHFSGLLACQTDRADAGIALMRASIAANPNAVYYNNLGNV
LLGRRQLGEAIEGYRQAVNLRPDYAEAHNNLGNALREAGDANAAMMSCATAIELRPGYAEAYNNLGNALKDLGDLGNAVL
AYQKAVSFRPDYADAFGNLARAEAGRGDADASIAAFRRALALDPDRADSYDSLAKLLHARGEIDAAIDTLQQATRRDPAD
AARHRLLAQWLLGRQRWDEAAHALTSAVELAPNDAAGYVELGDAYQHADKLDAAILCYRTATELAPRDAPAHHRLAVALL
KQRRADEALESAQKAVSLEPHSAVPHVNLGDVLSVLGDADGAIASYRRGIALDGEMELAHNRLLFDLATHAPTPPAVTLV
AAREFGARMAARARRCEHPAPQDDGRKLRIGFVSGDLQLHPVGIFIESVMEHFADGSFDLIAYSTRASEDDITARLKQRF
TAWRSLVNVRDEQAVQMIRDDGIDILVDLSGHTVHNRLPVFAWKPAPVQVSWLGYFGTTGLNEIDYVLGDPHVLPVAEES
HYVEKTWRLPDSYLCFTPPNVDVAVGPLPMTLSGHVTFGYFGKLVKITPNVIAAWSRLLRAVPGAKLMMKSHELGAAHAR
RSAAEQFAAQGIDALRLILEGGSPRHEYLKAYNRVDIMLSPFPYPGGTTTAEALWMGTPVVALQGDRFVTHICESVLNAA
GLGEWIARDEDEYIALASAWAAQRERLAVLRARLRAQTLASPLCDARRFATNLKAAFEGMWAQYVSRAA
>Mature_789_residues
MHDIPTLLNAALTHHQAGRLADAQALYDAILQTEPAQSDALHFSGLLACQTDRADAGIALMRASIAANPNAVYYNNLGNV
LLGRRQLGEAIEGYRQAVNLRPDYAEAHNNLGNALREAGDANAAMMSCATAIELRPGYAEAYNNLGNALKDLGDLGNAVL
AYQKAVSFRPDYADAFGNLARAEAGRGDADASIAAFRRALALDPDRADSYDSLAKLLHARGEIDAAIDTLQQATRRDPAD
AARHRLLAQWLLGRQRWDEAAHALTSAVELAPNDAAGYVELGDAYQHADKLDAAILCYRTATELAPRDAPAHHRLAVALL
KQRRADEALESAQKAVSLEPHSAVPHVNLGDVLSVLGDADGAIASYRRGIALDGEMELAHNRLLFDLATHAPTPPAVTLV
AAREFGARMAARARRCEHPAPQDDGRKLRIGFVSGDLQLHPVGIFIESVMEHFADGSFDLIAYSTRASEDDITARLKQRF
TAWRSLVNVRDEQAVQMIRDDGIDILVDLSGHTVHNRLPVFAWKPAPVQVSWLGYFGTTGLNEIDYVLGDPHVLPVAEES
HYVEKTWRLPDSYLCFTPPNVDVAVGPLPMTLSGHVTFGYFGKLVKITPNVIAAWSRLLRAVPGAKLMMKSHELGAAHAR
RSAAEQFAAQGIDALRLILEGGSPRHEYLKAYNRVDIMLSPFPYPGGTTTAEALWMGTPVVALQGDRFVTHICESVLNAA
GLGEWIARDEDEYIALASAWAAQRERLAVLRARLRAQTLASPLCDARRFATNLKAAFEGMWAQYVSRAA

Specific function: Unknown

COG id: COG3914

COG function: function code O; Predicted O-linked N-acetylglucosamine transferase, SPINDLY family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=597, Percent_Identity=28.643216080402, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI32307150, Length=597, Percent_Identity=28.643216080402, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI118766328, Length=248, Percent_Identity=29.4354838709677, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI118766330, Length=248, Percent_Identity=29.4354838709677, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI301336134, Length=371, Percent_Identity=26.9541778975741, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI83415184, Length=371, Percent_Identity=26.9541778975741, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI22749211, Length=335, Percent_Identity=26.865671641791, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI224809432, Length=337, Percent_Identity=23.4421364985163, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=597, Percent_Identity=27.1356783919598, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI115532692, Length=597, Percent_Identity=27.1356783919598, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25147174, Length=259, Percent_Identity=27.027027027027, Blast_Score=98, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319387, Length=198, Percent_Identity=25.2525252525253, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17647755, Length=518, Percent_Identity=28.7644787644788, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24585827, Length=518, Percent_Identity=28.7644787644788, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24585829, Length=518, Percent_Identity=28.7644787644788, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI281364285, Length=354, Percent_Identity=28.8135593220339, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581187, Length=354, Percent_Identity=28.8135593220339, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161076610, Length=330, Percent_Identity=28.7878787878788, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19920486, Length=330, Percent_Identity=28.7878787878788, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647123, Length=273, Percent_Identity=25.6410256410256, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24656717, Length=358, Percent_Identity=22.0670391061453, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI18110006, Length=358, Percent_Identity=22.0670391061453, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639187, Length=210, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 85758; Mature: 85758

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDIPTLLNAALTHHQAGRLADAQALYDAILQTEPAQSDALHFSGLLACQTDRADAGIAL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHCEEEEECCCCCCCHHH
MRASIAANPNAVYYNNLGNVLLGRRQLGEAIEGYRQAVNLRPDYAEAHNNLGNALREAGD
HHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
ANAAMMSCATAIELRPGYAEAYNNLGNALKDLGDLGNAVLAYQKAVSFRPDYADAFGNLA
CHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAEAGRGDADASIAAFRRALALDPDRADSYDSLAKLLHARGEIDAAIDTLQQATRRDPAD
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
AARHRLLAQWLLGRQRWDEAAHALTSAVELAPNDAAGYVELGDAYQHADKLDAAILCYRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
ATELAPRDAPAHHRLAVALLKQRRADEALESAQKAVSLEPHSAVPHVNLGDVLSVLGDAD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCC
GAIASYRRGIALDGEMELAHNRLLFDLATHAPTPPAVTLVAAREFGARMAARARRCEHPA
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
PQDDGRKLRIGFVSGDLQLHPVGIFIESVMEHFADGSFDLIAYSTRASEDDITARLKQRF
CCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHH
TAWRSLVNVRDEQAVQMIRDDGIDILVDLSGHTVHNRLPVFAWKPAPVQVSWLGYFGTTG
HHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCEECCCCCEEEECCCCEEEEEEEECCCCC
LNEIDYVLGDPHVLPVAEESHYVEKTWRLPDSYLCFTPPNVDVAVGPLPMTLSGHVTFGY
CCCHHHHCCCCCEEECCCCCHHHHHHHCCCCCEEEECCCCCCEEECCCCEEEECCEEHHH
FGKLVKITPNVIAAWSRLLRAVPGAKLMMKSHELGAAHARRSAAEQFAAQGIDALRLILE
HCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GGSPRHEYLKAYNRVDIMLSPFPYPGGTTTAEALWMGTPVVALQGDRFVTHICESVLNAA
CCCCHHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHC
GLGEWIARDEDEYIALASAWAAQRERLAVLRARLRAQTLASPLCDARRFATNLKAAFEGM
CCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAQYVSRAA
HHHHHHHCC
>Mature Secondary Structure
MHDIPTLLNAALTHHQAGRLADAQALYDAILQTEPAQSDALHFSGLLACQTDRADAGIAL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHCEEEEECCCCCCCHHH
MRASIAANPNAVYYNNLGNVLLGRRQLGEAIEGYRQAVNLRPDYAEAHNNLGNALREAGD
HHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
ANAAMMSCATAIELRPGYAEAYNNLGNALKDLGDLGNAVLAYQKAVSFRPDYADAFGNLA
CHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RAEAGRGDADASIAAFRRALALDPDRADSYDSLAKLLHARGEIDAAIDTLQQATRRDPAD
HHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
AARHRLLAQWLLGRQRWDEAAHALTSAVELAPNDAAGYVELGDAYQHADKLDAAILCYRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
ATELAPRDAPAHHRLAVALLKQRRADEALESAQKAVSLEPHSAVPHVNLGDVLSVLGDAD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCC
GAIASYRRGIALDGEMELAHNRLLFDLATHAPTPPAVTLVAAREFGARMAARARRCEHPA
CHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCC
PQDDGRKLRIGFVSGDLQLHPVGIFIESVMEHFADGSFDLIAYSTRASEDDITARLKQRF
CCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHH
TAWRSLVNVRDEQAVQMIRDDGIDILVDLSGHTVHNRLPVFAWKPAPVQVSWLGYFGTTG
HHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCEECCCCCEEEECCCCEEEEEEEECCCCC
LNEIDYVLGDPHVLPVAEESHYVEKTWRLPDSYLCFTPPNVDVAVGPLPMTLSGHVTFGY
CCCHHHHCCCCCEEECCCCCHHHHHHHCCCCCEEEECCCCCCEEECCCCEEEECCEEHHH
FGKLVKITPNVIAAWSRLLRAVPGAKLMMKSHELGAAHARRSAAEQFAAQGIDALRLILE
HCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHC
GGSPRHEYLKAYNRVDIMLSPFPYPGGTTTAEALWMGTPVVALQGDRFVTHICESVLNAA
CCCCHHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHC
GLGEWIARDEDEYIALASAWAAQRERLAVLRARLRAQTLASPLCDARRFATNLKAAFEGM
CCCHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WAQYVSRAA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105307 [H]