Click here to switch to the map view.

The map label for this gene is yrpG [H]

Identifier: 186477734

GI number: 186477734

Start: 3345324

End: 3346265

Strand: Reverse

Name: yrpG [H]

Synonym: Bphy_2988

Alternate gene names: 186477734

Gene position: 3346265-3345324 (Counterclockwise)

Preceding gene: 186477738

Following gene: 186477733

Centisome position: 96.18

GC content: 62.95

Gene sequence:

>942_bases
ATGCAGAAACGCAAGCTCGGCACGTCGTCATTGCAGGTCGTGCCGCTGATGTTTGGCGGCAATGTATTCGGCTGGACGGC
CGACGAAGCGACTTCGTTTTCGATCCTCGACGCCTTCGTCGACGCGGGCCTGAATTTCATCGATACGGCCGACGTCTATT
CGGCATGGGTGCCCGGCAATCACGGTGGTGAATCCGAGTCGATCATCGGAAAGTGGTTCGCGAAGTCAGGCAAGCGCGAC
AGAATCGTGCTGTCGACCAAGGTCGGCATGCTGGGAAGCCGCAAGGGGCTGTCGGCAGGCAATATTCGCGCAGCGGTCGA
GGATTCGCTGCGGCGCCTGCAGACGGACTACATCGACGTGTATTTCTCGCATATCGACGACACGGAGACGCCGCTCGCGG
AAACGCTCGGCGCATACCAGCAGTTGGTCGAAGCGGGCAAGGTGCGGGTGATCGGCGCGTCGAACTACGGCGGCCCGCGG
CTTCAGGAAGCCCTGCAGATCGCGCGCGACAACGGCTTGCCGCAATATCAGGTGATCCAGCCGGAATACAACCTGTACGA
CCGCGCCGGCTATGAAACCGATCTCGAACCGGTCGCGCTCGCCGAGCGGCTCGGCGTGGTCTGCTACTACAGCTTGGCGA
GCGGCTTCCTGTCGGGTAAATACCGTTCGCGCGACGATCTGTCGAGGAGCGCGCGCGGCCGTAAGGTCGAGGGGTATCTC
AACGAACGCGGCTTCGCGATCCTCGAGGCGCTGGATCACGTGGCGGGTGCGCATGGCAGCACACCGGCTTCCGTGGCGCT
CGCGTGGCTGATCGCGCGGCCCAGTATTACAGCGCCAATTGCCAGCGCGACATCCGTCCAACAGCTGGAAAGTCTCGTCG
CCGCTGTGCACCTGACGCTCACGGACGCCGATCTGCGCATGCTGAACGACGCAAGTGCCTGA

Upstream 100 bases:

>100_bases
CTCGCGAAATTTGGGGGCGTATGGTGCGGGCGGGGTGTCGATCACAGTCGCGAACAGCGCGTATGCTTGATGAACCGCTT
TCCTCGCTCATGGAGATGTC

Downstream 100 bases:

>100_bases
TCGTAAACGTCAAAAAGCTGGTCGGAGGGCTGTTTTCCTGATATGATCGGGAGTGAATTGAGATCTTTGCTCGTTTCGTC
ATGGGTTACTGGTGGCGAAA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MQKRKLGTSSLQVVPLMFGGNVFGWTADEATSFSILDAFVDAGLNFIDTADVYSAWVPGNHGGESESIIGKWFAKSGKRD
RIVLSTKVGMLGSRKGLSAGNIRAAVEDSLRRLQTDYIDVYFSHIDDTETPLAETLGAYQQLVEAGKVRVIGASNYGGPR
LQEALQIARDNGLPQYQVIQPEYNLYDRAGYETDLEPVALAERLGVVCYYSLASGFLSGKYRSRDDLSRSARGRKVEGYL
NERGFAILEALDHVAGAHGSTPASVALAWLIARPSITAPIASATSVQQLESLVAAVHLTLTDADLRMLNDASA

Sequences:

>Translated_313_residues
MQKRKLGTSSLQVVPLMFGGNVFGWTADEATSFSILDAFVDAGLNFIDTADVYSAWVPGNHGGESESIIGKWFAKSGKRD
RIVLSTKVGMLGSRKGLSAGNIRAAVEDSLRRLQTDYIDVYFSHIDDTETPLAETLGAYQQLVEAGKVRVIGASNYGGPR
LQEALQIARDNGLPQYQVIQPEYNLYDRAGYETDLEPVALAERLGVVCYYSLASGFLSGKYRSRDDLSRSARGRKVEGYL
NERGFAILEALDHVAGAHGSTPASVALAWLIARPSITAPIASATSVQQLESLVAAVHLTLTDADLRMLNDASA
>Mature_313_residues
MQKRKLGTSSLQVVPLMFGGNVFGWTADEATSFSILDAFVDAGLNFIDTADVYSAWVPGNHGGESESIIGKWFAKSGKRD
RIVLSTKVGMLGSRKGLSAGNIRAAVEDSLRRLQTDYIDVYFSHIDDTETPLAETLGAYQQLVEAGKVRVIGASNYGGPR
LQEALQIARDNGLPQYQVIQPEYNLYDRAGYETDLEPVALAERLGVVCYYSLASGFLSGKYRSRDDLSRSARGRKVEGYL
NERGFAILEALDHVAGAHGSTPASVALAWLIARPSITAPIASATSVQQLESLVAAVHLTLTDADLRMLNDASA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=29.6178343949045, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=29.5819935691318, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=28.2051282051282, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=28.2051282051282, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=28.2051282051282, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=29.0322580645161, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI223718702, Length=299, Percent_Identity=31.438127090301, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41152114, Length=299, Percent_Identity=31.7725752508361, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI41327764, Length=277, Percent_Identity=32.4909747292419, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI223718708, Length=169, Percent_Identity=33.1360946745562, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=311, Percent_Identity=35.048231511254, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789199, Length=329, Percent_Identity=30.6990881458967, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788070, Length=339, Percent_Identity=30.3834808259587, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=29.9382716049383, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=283, Percent_Identity=30.3886925795053, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=28.2674772036474, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=28.7390029325513, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6319958, Length=298, Percent_Identity=26.8456375838926, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319951, Length=329, Percent_Identity=25.531914893617, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321052, Length=160, Percent_Identity=33.125, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646155, Length=265, Percent_Identity=31.3207547169811, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33808; Mature: 33808

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRKLGTSSLQVVPLMFGGNVFGWTADEATSFSILDAFVDAGLNFIDTADVYSAWVPGN
CCCCCCCCCCEEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCEECHHHHHCCCCCC
HGGESESIIGKWFAKSGKRDRIVLSTKVGMLGSRKGLSAGNIRAAVEDSLRRLQTDYIDV
CCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YFSHIDDTETPLAETLGAYQQLVEAGKVRVIGASNYGGPRLQEALQIARDNGLPQYQVIQ
HHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEC
PEYNLYDRAGYETDLEPVALAERLGVVCYYSLASGFLSGKYRSRDDLSRSARGRKVEGYL
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEHHH
NERGFAILEALDHVAGAHGSTPASVALAWLIARPSITAPIASATSVQQLESLVAAVHLTL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEE
TDADLRMLNDASA
EHHHHHHHCCCCC
>Mature Secondary Structure
MQKRKLGTSSLQVVPLMFGGNVFGWTADEATSFSILDAFVDAGLNFIDTADVYSAWVPGN
CCCCCCCCCCEEEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCEECHHHHHCCCCCC
HGGESESIIGKWFAKSGKRDRIVLSTKVGMLGSRKGLSAGNIRAAVEDSLRRLQTDYIDV
CCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YFSHIDDTETPLAETLGAYQQLVEAGKVRVIGASNYGGPRLQEALQIARDNGLPQYQVIQ
HHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEC
PEYNLYDRAGYETDLEPVALAERLGVVCYYSLASGFLSGKYRSRDDLSRSARGRKVEGYL
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEHHH
NERGFAILEALDHVAGAHGSTPASVALAWLIARPSITAPIASATSVQQLESLVAAVHLTL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEE
TDADLRMLNDASA
EHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]