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The map label for this gene is argC [H]

Identifier: 186477623

GI number: 186477623

Start: 3229618

End: 3230565

Strand: Direct

Name: argC [H]

Synonym: Bphy_2875

Alternate gene names: 186477623

Gene position: 3229618-3230565 (Clockwise)

Preceding gene: 186477622

Following gene: 186477626

Centisome position: 92.83

GC content: 64.56

Gene sequence:

>948_bases
ATGAGCACGAAAGTTTTTGTCGACGGACAGGAAGGCACGACTGGCCTGAAGATCTTCGAATACCTGTCGCAGCGCGCAGA
CGTTGAAATCCTCCGCATCGAAGAAGCGAAGCGCAAGGATATCGACGAGCGCCGTCGTCTCATCAACGCATCCGACGTCA
CGTTTCTGTGCCTGCCGGACGTCGCGTCGCGCGAATCGGCGTCGCTGGTCGAGAACGACCGCACGGTGCTGATCGACGCG
AGCACGGCTTTCCGCACCAGCGCCGACTGGGCGTACGGCCTGCCTGAACTCACACGCGCGCAACGCGAGCGCCTGCGCAC
GGCCAAACGCGTCGCGGTGCCGGGCTGCCATGCGTCGGCGTTCGTACTGGCCATGCGCCCCCTCGTCGAAGCGGGCGTCG
TGCCGGCCGACTTCGCCGCGCACAGCTATTCGATCACCGGCTACAGCGGCGGCGGCAAGAAAATGATCGCGGATTATGAA
GCGGGCGGTAACCCGAAGCTCGACAGCCCGCGTCCCTACGCACTCGGCCTCACCCACAAGCATCTGCCGGAAATGGCCGC
GCACACGGGCCTGAAAAGCGCGCCGATCTTCACGCCGATCGTCGGCAGCTTCTACAAGGGCCTCGCCGTCACGACGTATT
TCACGCCCAGCCAGCTTGCCAAGCCGACCACGCCGCAAGACGTGCAGGCTCTCTTCGCCGAATATTACGGCGGCGAGCAG
TTCGTGCGCGTTGCGCCGTACAACGCCGACGACAACCTCGACAGCGGCTTCTTCGACGTGCAGGCGAACAACGACACCAA
CCGCGTCGACCTGTTCGTGTTCGGCAATGAAGAGCGCTTCGTGACCGTCGCGCGGCTCGATAACCTGGGCAAGGGCGCGT
CGGGCGCAGCGATCCAGTGCATGAACCTCGCGATCGGCGCGGACGAAGCCGCAGGCCTCACGCGCTAA

Upstream 100 bases:

>100_bases
CTGCCGATTCCGCGCGCACGCCGCCGCACGGTCTTAAAATAGCGTTCCGGCGCCCGTGGCGCCCCGTTTTACCGCCGTTT
TACCAGCCAGCGAGATTGAG

Downstream 100 bases:

>100_bases
ACGCATCCCCGCGACGGCTCACGCCGTCCCGCACACGACAAAGCCGGCATTCACGCGCCGGCTTTTTCTTTGGCTTATCA
GTCCGCGATTCGAAGCGACT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSTKVFVDGQEGTTGLKIFEYLSQRADVEILRIEEAKRKDIDERRRLINASDVTFLCLPDVASRESASLVENDRTVLIDA
STAFRTSADWAYGLPELTRAQRERLRTAKRVAVPGCHASAFVLAMRPLVEAGVVPADFAAHSYSITGYSGGGKKMIADYE
AGGNPKLDSPRPYALGLTHKHLPEMAAHTGLKSAPIFTPIVGSFYKGLAVTTYFTPSQLAKPTTPQDVQALFAEYYGGEQ
FVRVAPYNADDNLDSGFFDVQANNDTNRVDLFVFGNEERFVTVARLDNLGKGASGAAIQCMNLAIGADEAAGLTR

Sequences:

>Translated_315_residues
MSTKVFVDGQEGTTGLKIFEYLSQRADVEILRIEEAKRKDIDERRRLINASDVTFLCLPDVASRESASLVENDRTVLIDA
STAFRTSADWAYGLPELTRAQRERLRTAKRVAVPGCHASAFVLAMRPLVEAGVVPADFAAHSYSITGYSGGGKKMIADYE
AGGNPKLDSPRPYALGLTHKHLPEMAAHTGLKSAPIFTPIVGSFYKGLAVTTYFTPSQLAKPTTPQDVQALFAEYYGGEQ
FVRVAPYNADDNLDSGFFDVQANNDTNRVDLFVFGNEERFVTVARLDNLGKGASGAAIQCMNLAIGADEAAGLTR
>Mature_314_residues
STKVFVDGQEGTTGLKIFEYLSQRADVEILRIEEAKRKDIDERRRLINASDVTFLCLPDVASRESASLVENDRTVLIDAS
TAFRTSADWAYGLPELTRAQRERLRTAKRVAVPGCHASAFVLAMRPLVEAGVVPADFAAHSYSITGYSGGGKKMIADYEA
GGNPKLDSPRPYALGLTHKHLPEMAAHTGLKSAPIFTPIVGSFYKGLAVTTYFTPSQLAKPTTPQDVQALFAEYYGGEQF
VRVAPYNADDNLDSGFFDVQANNDTNRVDLFVFGNEERFVTVARLDNLGKGASGAAIQCMNLAIGADEAAGLTR

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=282, Percent_Identity=28.7234042553192, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320913, Length=312, Percent_Identity=28.2051282051282, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 34211; Mature: 34080

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKVFVDGQEGTTGLKIFEYLSQRADVEILRIEEAKRKDIDERRRLINASDVTFLCLPD
CCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCHHHCCHHHHHHHCCCCCEEEEECCC
VASRESASLVENDRTVLIDASTAFRTSADWAYGLPELTRAQRERLRTAKRVAVPGCHASA
CCCCCCHHHHCCCCEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
FVLAMRPLVEAGVVPADFAAHSYSITGYSGGGKKMIADYEAGGNPKLDSPRPYALGLTHK
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCHH
HLPEMAAHTGLKSAPIFTPIVGSFYKGLAVTTYFTPSQLAKPTTPQDVQALFAEYYGGEQ
HHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECHHHHCCCCCHHHHHHHHHHHCCCCE
FVRVAPYNADDNLDSGFFDVQANNDTNRVDLFVFGNEERFVTVARLDNLGKGASGAAIQC
EEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEHHCCCCCCCCCEEEE
MNLAIGADEAAGLTR
EEEEECCCHHCCCCC
>Mature Secondary Structure 
STKVFVDGQEGTTGLKIFEYLSQRADVEILRIEEAKRKDIDERRRLINASDVTFLCLPD
CCEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCHHHCCHHHHHHHCCCCCEEEEECCC
VASRESASLVENDRTVLIDASTAFRTSADWAYGLPELTRAQRERLRTAKRVAVPGCHASA
CCCCCCHHHHCCCCEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHH
FVLAMRPLVEAGVVPADFAAHSYSITGYSGGGKKMIADYEAGGNPKLDSPRPYALGLTHK
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCHH
HLPEMAAHTGLKSAPIFTPIVGSFYKGLAVTTYFTPSQLAKPTTPQDVQALFAEYYGGEQ
HHHHHHHHCCCCCCCCHHHHHHHHHCCEEEEEEECHHHHCCCCCHHHHHHHHHHHCCCCE
FVRVAPYNADDNLDSGFFDVQANNDTNRVDLFVFGNEERFVTVARLDNLGKGASGAAIQC
EEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEHHCCCCCCCCCEEEE
MNLAIGADEAAGLTR
EEEEECCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]